Gene name: GAD1
Reference locus (S288C): YMR250W
Gene biotype: protein_coding
Description: Glutamate decarboxylase; converts glutamate into gamma-aminobutyric acid (GABA) during glutamate catabolism; involved in response to oxidative stress
Top 10 interactors (score): UGA1 (0.999); ALD3 (0.994); MSC1 (0.989); GDH2 (0.988); ALD4 (0.986); TSL1 (0.986); SOL4 (0.979); TFS1 (0.978); DCS2 (0.975); PGM2 (0.974); CTT1 (0.968); GDH3 (0.967); HSP26 (0.963); HFD1 (0.962); GDH1 (0.959); RTC3 (0.957); NNR1 (0.954); PAN6 (0.953); HSP12 (0.953); GDB1 (0.953)
Homologues (species, bitscore): SGPL1 (Homo sapiens, 70.1); Sgpl1 (Mus musculus, 78.2); sgpl1 (Danio rerio, 69.7); sgpl1 (Xenopus tropicalis, 72.8); Sply (Drosophila melanogaster, 80.5); tag-38 (Caenorhabditis elegans, 79.0); GAD (Arabidopsis thaliana, 341.3)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:810265-812022:+ | gene-YMR250W_AKU4011 | rna-NM_001182756.1_AKU4011 | cds-NP_013976.1_AKU4011 | 98.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000069.1:142466-144223:- | gene-YMR250W_BG1 | rna-NM_001182756.1_BG1 | cds-NP_013976.1_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:755478-757235:+ | gene-YMR250W_Bruggeman | rna-NM_001182756.1_Bruggeman | cds-NP_013976.1_Bruggeman | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:758490-760247:+ | gene-YMR250W_CAT1 | rna-NM_001182756.1_CAT1 | cds-NP_013976.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:742525-744282:+ | gene-YMR250W_CBS1585 | rna-NM_001182756.1_CBS1585 | cds-NP_013976.1_CBS1585 | 98.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:747510-749267:+ | gene-YMR250W_CBS436 | rna-NM_001182756.1_CBS436 | cds-NP_013976.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:854082-855839:+ | gene-YMR250W_CBS6412 | rna-NM_001182756.1_CBS6412 | cds-NP_013976.1_CBS6412 | 98.4 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:741676-743433:+ | gene-YMR250W_CBS6413 | rna-NM_001182756.1_CBS6413 | cds-NP_013976.1_CBS6413 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:765127-766884:+ | gene-YMR250W_CENPK1137D | rna-NM_001182756.1_CENPK1137D | cds-NP_013976.1_CENPK1137D | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:802927-804684:+ | gene-YMR250W_EthanolRed | rna-NM_001182756.1_EthanolRed | cds-NP_013976.1_EthanolRed | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:748952-750709:+ | gene-YMR250W_FaliES1 | rna-NM_001182756.1_FaliES1 | cds-NP_013976.1_FaliES1 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000141.1:35802-37559:- | gene-YMR250W_JAY291 | rna-NM_001182756.1_JAY291 | cds-NP_013976.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:749313-751070:+ | gene-YMR250W_MUCL30387 | rna-NM_001182756.1_MUCL30387 | cds-NP_013976.1_MUCL30387 | 98.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005451.1:757240-758997:+ | gene-YMR250W_MUCL30388 | rna-NM_001182756.1_MUCL30388 | cds-NP_013976.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:743595-745352:+ | gene-YMR250W_MUCL39482 | rna-NM_001182756.1_MUCL39482 | cds-NP_013976.1_MUCL39482 | 98.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:751017-752774:+ | gene-YMR250W_MUCL42920 | rna-NM_001182756.1_MUCL42920 | cds-NP_013976.1_MUCL42920 | 98.9 | 100.0 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:770755-772512:+ | gene-YMR250W_NCIM3186 | rna-NM_001182756.1_NCIM3186 | cds-NP_013976.1_NCIM3186 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:743250-745007:+ | gene-YMR250W_NCYC1407 | rna-NM_001182756.1_NCYC1407 | cds-NP_013976.1_NCYC1407 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:753209-754966:+ | gene-YMR250W_PE2H3 | rna-NM_001182756.1_PE2H3 | cds-NP_013976.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:754252-756009:+ | gene-YMR250W_PE2H4 | rna-NM_001182756.1_PE2H4 | cds-NP_013976.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:770801-772558:+ | gene-YMR250W_S288C | rna-NM_001182756.1_S288C | cds-NP_013976.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000002.1:35917-37674:- | gene-YMR250W_SA1 | rna-NM_001182756.1_SA1 | cds-NP_013976.1_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:745124-746881:+ | gene-YMR250W_ThermosaccDry | rna-NM_001182756.1_ThermosaccDry | cds-NP_013976.1_ThermosaccDry | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:757740-759497:+ | gene-YMR250W_VR1 | rna-NM_001182756.1_VR1 | cds-NP_013976.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000028.1:160327-162084:+ | gene-YMR250W_ZTW1 | rna-NM_001182756.1_ZTW1 | cds-NP_013976.1_ZTW1 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:763549-765306:+ | gene-YMR250W_Sparadoxus | rna-NM_001182756.1_Sparadoxus | cds-NP_013976.1_Sparadoxus | 89.2 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |