GAC1 (YOR178C)


Gene profile

Gene name: GAC1
Reference locus (S288C): YOR178C
Gene biotype: protein_coding

Description: Regulatory subunit for Glc7p type-1 protein phosphatase (PP1); tethers Glc7p to Gsy2p glycogen synthase, binds Hsf1p heat shock transcription factor, required for induction of some HSF-regulated genes under heat shock; GAC1 has a paralog, PIG1, that arose from the whole genome duplication

Top 10 interactors (score): GLC7 (0.999); GSY2 (0.985); GIP2 (0.982); SDS22 (0.975); PIG2 (0.974); SIT4 (0.955); GLC3 (0.951); PPH21 (0.948); GIP1 (0.947); PIG1 (0.947); PPH3 (0.934); REG2 (0.931); CNA1 (0.931); CMP2 (0.931); RRD2 (0.915); ISF1 (0.908); CDC55 (0.908); TPD3 (0.905); CNB1 (0.904); PSY2 (0.9)

Homologues (species, bitscore): PPP1R3C (Homo sapiens, 68.6); Ppp1r3c (Mus musculus, 68.2); ppp1r3cb (Danio rerio, 62.0); ppp1r3c.1 (Xenopus tropicalis, 57.0); Gbs-76A (Drosophila melanogaster, 51.2); H18N23.2 (Caenorhabditis elegans, 51.6)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005309.1:665169-667571:- gene-YOR178C_AKU4011 rna-NM_001183597.3_AKU4011 cds-NP_014821.3_AKU4011 98.4 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000123.1:67287-69668:- gene-YOR178C_BG1 rna-NM_001183597.3_BG1 cds-NP_014821.3_BG1 99.8 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005517.1:649206-651587:- gene-YOR178C_Bruggeman rna-NM_001183597.3_Bruggeman cds-NP_014821.3_Bruggeman 99.7 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005533.1:650376-652757:- gene-YOR178C_CAT1 rna-NM_001183597.3_CAT1 cds-NP_014821.3_CAT1 99.5 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005373.1:648158-650560:- gene-YOR178C_CBS1585 rna-NM_001183597.3_CBS1585 cds-NP_014821.3_CBS1585 98.4 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005357.1:646288-648687:- gene-YOR178C_CBS436 rna-NM_001183597.3_CBS436 cds-NP_014821.3_CBS436 98.4 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005341.1:645272-647674:- gene-YOR178C_CBS6412 rna-NM_001183597.3_CBS6412 cds-NP_014821.3_CBS6412 98.4 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005325.1:653946-656354:- gene-YOR178C_CBS6413 rna-NM_001183597.3_CBS6413 cds-NP_014821.3_CBS6413 98.0 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001536.1:667616-669997:- gene-YOR178C_CENPK1137D rna-NM_001183597.3_CENPK1137D cds-NP_014821.3_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005485.1:641141-643546:- gene-YOR178C_EthanolRed rna-NM_001183597.3_EthanolRed cds-NP_014821.3_EthanolRed 98.1 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005549.1:646214-648619:- gene-YOR178C_FaliES1 rna-NM_001183597.3_FaliES1 cds-NP_014821.3_FaliES1 98.1 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000038.1:28915-31296:+ gene-YOR178C_JAY291 rna-NM_001183597.3_JAY291 cds-NP_014821.3_JAY291 99.3 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005421.1:654013-656394:- gene-YOR178C_MUCL30387 rna-NM_001183597.3_MUCL30387 cds-NP_014821.3_MUCL30387 99.7 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005453.1:661422-663803:- gene-YOR178C_MUCL30388 rna-NM_001183597.3_MUCL30388 cds-NP_014821.3_MUCL30388 99.7 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005293.1:655494-657902:- gene-YOR178C_MUCL39482 rna-NM_001183597.3_MUCL39482 cds-NP_014821.3_MUCL39482 98.0 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005437.1:664895-667276:- gene-YOR178C_MUCL42920 rna-NM_001183597.3_MUCL42920 cds-NP_014821.3_MUCL42920 99.9 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011824.1:667749-670130:- gene-YOR178C_NCIM3186 rna-NM_001183597.3_NCIM3186 cds-NP_014821.3_NCIM3186 99.2 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005277.1:655584-657986:- gene-YOR178C_NCYC1407 rna-NM_001183597.3_NCYC1407 cds-NP_014821.3_NCYC1407 98.4 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994154.1:654434-656815:- gene-YOR178C_PE2H3 rna-NM_001183597.3_PE2H3 cds-NP_014821.3_PE2H3 99.3 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999886.1:664811-667192:- gene-YOR178C_PE2H4 rna-NM_001183597.3_PE2H4 cds-NP_014821.3_PE2H4 99.3 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001147.6:667860-670241:- gene-YOR178C_S288C rna-NM_001183597.3_S288C cds-NP_014821.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000006.1:84430-86811:- gene-YOR178C_SA1 rna-NM_001183597.3_SA1 cds-NP_014821.3_SA1 99.8 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005501.1:645397-647802:- gene-YOR178C_ThermosaccDry rna-NM_001183597.3_ThermosaccDry cds-NP_014821.3_ThermosaccDry 98.1 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005469.1:709465-711846:- gene-YOR178C_VR1 rna-NM_001183597.3_VR1 cds-NP_014821.3_VR1 99.8 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000032.1:378823-381212:- gene-YOR178C_ZTW1 rna-NM_001183597.3_ZTW1 cds-NP_014821.3_ZTW1 98.9 100.0 Unannotated 1 1 0 False False False True False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047501.1:650897-653290:- gene-YOR178C_Sparadoxus rna-NM_001183597.3_Sparadoxus cds-NP_014821.3_Sparadoxus 84.9 99.6 Verified 1 1 1 False True False False False

Additional files