Gene name: GAA1
Reference locus (S288C): YLR088W
Gene biotype: protein_coding
Description: Subunit of the GPI:protein transamidase complex; removes the GPI-anchoring signal and attaches GPI (glycosylphosphatidylinositol) to proteins in the ER; human homolog GPAA1 can complement growth defects of yeast thermosensitive mutant at restrictive temperature
Top 10 interactors (score): GAB1 (0.999); GPI16 (0.999); GPI17 (0.999); GPI8 (0.999); GPI13 (0.989); BST1 (0.989); GPI10 (0.98); GPI11 (0.967); SMP3 (0.962); GPI12 (0.927); GPI14 (0.925); GPI19 (0.922); GPI18 (0.919); SPT14 (0.913); ALG12 (0.861); GPI2 (0.812); TSC10 (0.78); ALG9 (0.76); GPI1 (0.726); LAS21 (0.715)
Homologues (species, bitscore): GPAA1 (Homo sapiens, 164.1); Gpaa1 (Mus musculus, 160.6); GPAA1 (Danio rerio, 147.9); gpaa1 (Xenopus tropicalis, 142.9); GAA1 (Drosophila melanogaster, 148.3); hpo-3 (Caenorhabditis elegans, 73.9); AT5G19130 (Arabidopsis thaliana, 124.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:298579-300423:+ | gene-YLR088W_AKU4011 | rna-NM_001181975.1_AKU4011 | cds-NP_013189.1_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000212.1:261749-263593:+ | gene-YLR088W_BG1 | rna-NM_001181975.1_BG1 | cds-NP_013189.1_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:308487-310331:+ | gene-YLR088W_Bruggeman | rna-NM_001181975.1_Bruggeman | cds-NP_013189.1_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:308806-310650:+ | gene-YLR088W_CAT1 | rna-NM_001181975.1_CAT1 | cds-NP_013189.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:305693-307537:+ | gene-YLR088W_CBS1585 | rna-NM_001181975.1_CBS1585 | cds-NP_013189.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:296314-298158:+ | gene-YLR088W_CBS436 | rna-NM_001181975.1_CBS436 | cds-NP_013189.1_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:304134-305978:+ | gene-YLR088W_CBS6412 | rna-NM_001181975.1_CBS6412 | cds-NP_013189.1_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:305965-307809:+ | gene-YLR088W_CBS6413 | rna-NM_001181975.1_CBS6413 | cds-NP_013189.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:301114-302958:+ | gene-YLR088W_CENPK1137D | rna-NM_001181975.1_CENPK1137D | cds-NP_013189.1_CENPK1137D | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:298098-299942:+ | gene-YLR088W_EthanolRed | rna-NM_001181975.1_EthanolRed | cds-NP_013189.1_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:297974-299818:+ | gene-YLR088W_FaliES1 | rna-NM_001181975.1_FaliES1 | cds-NP_013189.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000129.1:72914-74758:+ | gene-YLR088W_JAY291 | rna-NM_001181975.1_JAY291 | cds-NP_013189.1_JAY291 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:305849-307693:+ | gene-YLR088W_MUCL30387 | rna-NM_001181975.1_MUCL30387 | cds-NP_013189.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:313499-315343:+ | gene-YLR088W_MUCL30388 | rna-NM_001181975.1_MUCL30388 | cds-NP_013189.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:306211-308055:+ | gene-YLR088W_MUCL39482 | rna-NM_001181975.1_MUCL39482 | cds-NP_013189.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:306134-307978:+ | gene-YLR088W_MUCL42920 | rna-NM_001181975.1_MUCL42920 | cds-NP_013189.1_MUCL42920 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:316081-317925:+ | gene-YLR088W_NCIM3186 | rna-NM_001181975.1_NCIM3186 | cds-NP_013189.1_NCIM3186 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:298282-300126:+ | gene-YLR088W_NCYC1407 | rna-NM_001181975.1_NCYC1407 | cds-NP_013189.1_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:304147-305991:+ | gene-YLR088W_PE2H3 | rna-NM_001181975.1_PE2H3 | cds-NP_013189.1_PE2H3 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:303888-305732:+ | gene-YLR088W_PE2H4 | rna-NM_001181975.1_PE2H4 | cds-NP_013189.1_PE2H4 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:316107-317951:+ | gene-YLR088W_S288C | rna-NM_001181975.1_S288C | cds-NP_013189.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000033.1:56167-58011:- | gene-YLR088W_SA1 | rna-NM_001181975.1_SA1 | cds-NP_013189.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:298150-299994:+ | gene-YLR088W_ThermosaccDry | rna-NM_001181975.1_ThermosaccDry | cds-NP_013189.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:312335-314179:+ | gene-YLR088W_VR1 | rna-NM_001181975.1_VR1 | cds-NP_013189.1_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000023.1:297531-299375:+ | gene-YLR088W_ZTW1 | rna-NM_001181975.1_ZTW1 | cds-NP_013189.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:306371-308215:+ | gene-YLR088W_Sparadoxus | rna-NM_001181975.1_Sparadoxus | cds-NP_013189.1_Sparadoxus | 90.9 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |