FZF1 (YGL254W)


Gene profile

Gene name: FZF1
Reference locus (S288C): YGL254W
Gene biotype: protein_coding

Description: Zinc finger protein FZF1; Transcription factor involved in sulfite metabolism; sole identified regulatory target is SSU1; overexpression suppresses sulfite-sensitivity of many unrelated mutants due to hyperactivation of SSU1, contains five zinc fingers; protein abundance increases in response to DNA replication stress

Top 10 interactors (score): SSU1 (0.97); MET1 (0.9); YHB1 (0.759); ECM34 (0.748); BRF1 (0.719); RPO31 (0.718); TFC4 (0.708); PAU11 (0.694); TFC1 (0.66); SPT15 (0.645); RPB10 (0.637); RPC11 (0.635); GRR1 (0.633); CST6 (0.617); RPB8 (0.617); RPC40 (0.611); RET1 (0.609); RPC37 (0.608); BDP1 (0.607); RPB5 (0.607)

Homologues (species, bitscore): KLF15 (Homo sapiens, 80.1); Klf15 (Mus musculus, 80.9); LOC556200 (Danio rerio, 81.3); klf15 (Xenopus tropicalis, 81.6); Bteb2 (Drosophila melanogaster, 82.8); klf-2 (Caenorhabditis elegans, 72.0); YY1 (Arabidopsis thaliana, 60.8)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005301.1:23815-24714:+ gene-YGL254W_AKU4011 rna-NM_001181120.1_AKU4011 cds-NP_011260.1_AKU4011 99.8 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000175.1:15858-16757:+ gene-YGL254W_BG1 rna-NM_001181120.1_BG1 cds-NP_011260.1_BG1 99.7 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005509.1:24182-25081:+ gene-YGL254W_Bruggeman rna-NM_001181120.1_Bruggeman cds-NP_011260.1_Bruggeman 99.3 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005525.1:22246-23145:+ gene-YGL254W_CAT1 rna-NM_001181120.1_CAT1 cds-NP_011260.1_CAT1 99.7 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005365.1:28103-29002:+ gene-YGL254W_CBS1585 rna-NM_001181120.1_CBS1585 cds-NP_011260.1_CBS1585 99.8 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005349.1:22843-23742:+ gene-YGL254W_CBS436 rna-NM_001181120.1_CBS436 cds-NP_011260.1_CBS436 99.3 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005333.1:15671-16570:+ gene-YGL254W_CBS6412 rna-NM_001181120.1_CBS6412 cds-NP_011260.1_CBS6412 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005317.1:21959-22858:+ gene-YGL254W_CBS6413 rna-NM_001181120.1_CBS6413 cds-NP_011260.1_CBS6413 99.8 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001528.1:21966-22865:+ gene-YGL254W_CENPK1137D rna-NM_001181120.1_CENPK1137D cds-NP_011260.1_CENPK1137D 98.8 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005477.1:15092-15991:+ gene-YGL254W_EthanolRed rna-NM_001181120.1_EthanolRed cds-NP_011260.1_EthanolRed 100.0 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005541.1:15453-16352:+ gene-YGL254W_FaliES1 rna-NM_001181120.1_FaliES1 cds-NP_011260.1_FaliES1 100.0 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000079.1:50717-51616:- gene-YGL254W_JAY291 rna-NM_001181120.1_JAY291 cds-NP_011260.1_JAY291 99.3 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005413.1:24118-25017:+ gene-YGL254W_MUCL30387 rna-NM_001181120.1_MUCL30387 cds-NP_011260.1_MUCL30387 99.3 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005445.1:26270-27169:+ gene-YGL254W_MUCL30388 rna-NM_001181120.1_MUCL30388 cds-NP_011260.1_MUCL30388 99.7 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005285.1:24700-25599:+ gene-YGL254W_MUCL39482 rna-NM_001181120.1_MUCL39482 cds-NP_011260.1_MUCL39482 99.8 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005429.1:27605-28504:+ gene-YGL254W_MUCL42920 rna-NM_001181120.1_MUCL42920 cds-NP_011260.1_MUCL42920 99.3 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011816.1:22304-23203:+ gene-YGL254W_NCIM3186 rna-NM_001181120.1_NCIM3186 cds-NP_011260.1_NCIM3186 99.3 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005269.1:16464-17363:+ gene-YGL254W_NCYC1407 rna-NM_001181120.1_NCYC1407 cds-NP_011260.1_NCYC1407 99.8 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994146.1:18331-19230:+ gene-YGL254W_PE2H3 rna-NM_001181120.1_PE2H3 cds-NP_011260.1_PE2H3 98.8 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999878.1:17879-18778:+ gene-YGL254W_PE2H4 rna-NM_001181120.1_PE2H4 cds-NP_011260.1_PE2H4 98.8 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001139.9:22304-23203:+ gene-YGL254W_S288C rna-NM_001181120.1_S288C cds-NP_011260.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000002.1:352141-353040:- gene-YGL254W_SA1 rna-NM_001181120.1_SA1 cds-NP_011260.1_SA1 99.7 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005493.1:15768-16667:+ gene-YGL254W_ThermosaccDry rna-NM_001181120.1_ThermosaccDry cds-NP_011260.1_ThermosaccDry 100.0 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005461.1:22761-23660:+ gene-YGL254W_VR1 rna-NM_001181120.1_VR1 cds-NP_011260.1_VR1 99.7 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000014.1:14842-15741:+ gene-YGL254W_ZTW1 rna-NM_001181120.1_ZTW1 cds-NP_011260.1_ZTW1 99.8 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047493.1:23538-24437:+ gene-YGL254W_Sparadoxus rna-NM_001181120.1_Sparadoxus cds-NP_011260.1_Sparadoxus 81.9 98.7 Verified 1 1 1 False True False False False

Additional files