Gene name: FUN30
Reference locus (S288C): YAL019W
Gene biotype: protein_coding
Description: Swi/snf-related matrix-associated actin-dependent regulator of chromatin subfamily a containing dead/h box 1; ATP-dependent helicase FUN30; Snf2p family member with ATP-dependent chromatin remodeling activity; has a role in silencing at the mating type locus, telomeres and centromeres; enriched at centromeres and is required for correct chromatin structure around centromeres, as well as at the boundary element of the silent HMR; recruited to DNA double-strand breaks (DSBs) where it promotes 5' strand resection of DSBs; potential Cdc28p substrate
Top 10 interactors (score): MAK16 (0.98); MSH2 (0.98); EXO1 (0.973); DNA2 (0.953); SGS1 (0.896); POL1 (0.883); RAD9 (0.882); HTA1 (0.873); HTA2 (0.839); HHT1 (0.808); ISW1 (0.787); DPB11 (0.774); HHT2 (0.766); HTZ1 (0.757); RMI1 (0.722); ORC5 (0.719); DRS1 (0.71); RSC2 (0.706); SAE2 (0.702); YLR419W (0.697)
Homologues (species, bitscore): SMARCAD1 (Homo sapiens, 449.5); Smarcad1 (Mus musculus, 448.7); LOC563175 (Danio rerio, 458.4); smarcad1 (Xenopus tropicalis, 428.7); Etl1 (Drosophila melanogaster, 380.2); M03C11.8 (Caenorhabditis elegans, 434.1); ETL1 (Arabidopsis thaliana, 345.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005295.1:100032-103427:+ | gene-YAL019W_AKU4011 | rna-NM_001178164.1_AKU4011 | cds-NP_009383.1_AKU4011 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000070.1:86980-90375:+ | gene-YAL019W_BG1 | rna-NM_001178164.1_BG1 | cds-NP_009383.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005503.1:114903-118298:+ | gene-YAL019W_Bruggeman | rna-NM_001178164.1_Bruggeman | cds-NP_009383.1_Bruggeman | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005519.1:101240-104635:+ | gene-YAL019W_CAT1 | rna-NM_001178164.1_CAT1 | cds-NP_009383.1_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005359.1:113051-116446:+ | gene-YAL019W_CBS1585 | rna-NM_001178164.1_CBS1585 | cds-NP_009383.1_CBS1585 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005343.1:113320-116715:+ | gene-YAL019W_CBS436 | rna-NM_001178164.1_CBS436 | cds-NP_009383.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:726138-729533:+ | gene-YAL019W_CBS6412 | rna-NM_001178164.1_CBS6412 | cds-NP_009383.1_CBS6412 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005311.1:111314-114709:+ | gene-YAL019W_CBS6413 | rna-NM_001178164.1_CBS6413 | cds-NP_009383.1_CBS6413 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001522.1:115077-118472:+ | gene-YAL019W_CENPK1137D | rna-NM_001178164.1_CENPK1137D | cds-NP_009383.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005471.1:101453-104848:+ | gene-YAL019W_EthanolRed | rna-NM_001178164.1_EthanolRed | cds-NP_009383.1_EthanolRed | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005535.1:116077-119472:+ | gene-YAL019W_FaliES1 | rna-NM_001178164.1_FaliES1 | cds-NP_009383.1_FaliES1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000084.1:87348-90743:+ | gene-YAL019W_JAY291 | rna-NM_001178164.1_JAY291 | cds-NP_009383.1_JAY291 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005407.1:116030-119425:+ | gene-YAL019W_MUCL30387 | rna-NM_001178164.1_MUCL30387 | cds-NP_009383.1_MUCL30387 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005439.1:112552-115947:+ | gene-YAL019W_MUCL30388 | rna-NM_001178164.1_MUCL30388 | cds-NP_009383.1_MUCL30388 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005279.1:111833-115228:+ | gene-YAL019W_MUCL39482 | rna-NM_001178164.1_MUCL39482 | cds-NP_009383.1_MUCL39482 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005423.1:114212-117607:+ | gene-YAL019W_MUCL42920 | rna-NM_001178164.1_MUCL42920 | cds-NP_009383.1_MUCL42920 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011810.1:114796-118191:+ | gene-YAL019W_NCIM3186 | rna-NM_001178164.1_NCIM3186 | cds-NP_009383.1_NCIM3186 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005263.1:99722-103117:+ | gene-YAL019W_NCYC1407 | rna-NM_001178164.1_NCYC1407 | cds-NP_009383.1_NCYC1407 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994140.1:101636-105031:+ | gene-YAL019W_PE2H3 | rna-NM_001178164.1_PE2H3 | cds-NP_009383.1_PE2H3 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999872.1:101355-104750:+ | gene-YAL019W_PE2H4 | rna-NM_001178164.1_PE2H4 | cds-NP_009383.1_PE2H4 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001133.9:114919-118314:+ | gene-YAL019W_S288C | rna-NM_001178164.1_S288C | cds-NP_009383.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000077.1:31788-35183:+ | gene-YAL019W_SA1 | rna-NM_001178164.1_SA1 | cds-NP_009383.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005487.1:115590-118985:+ | gene-YAL019W_ThermosaccDry | rna-NM_001178164.1_ThermosaccDry | cds-NP_009383.1_ThermosaccDry | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005455.1:116880-120275:+ | gene-YAL019W_VR1 | rna-NM_001178164.1_VR1 | cds-NP_009383.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000002.1:87401-90797:+ | gene-YAL019W_ZTW1 | rna-NM_001178164.1_ZTW1 | cds-NP_009383.1_ZTW1 | 99.1 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047487.1:104968-108342:+ | gene-YAL019W_Sparadoxus | rna-NM_001178164.1_Sparadoxus | cds-NP_009383.1_Sparadoxus | 90.5 | 99.2 | Verified | 1 | 1 | 1 | False | True | False | False | False |