FUN14 (YAL008W)


Gene profile

Gene name: FUN14
Reference locus (S288C): YAL008W
Gene biotype: protein_coding

Description: Protein FUN14; Integral mitochondrial outer membrane (MOM) protein; dosage suppressor of an MDM10 null that reduces ERMES-related phenotypes, such as alterations in mitochondrial morphology, protein complex assembly, and lipid profile; dosage suppressor of MDM12, MDM34, and MMM1 null mutant growth defects; novel mechanism of MOM import involving Tom70p, the TOM complex, and the TIM23 complex, requiring mitochondrial membrane potential and processing by the IMP complex for correct biogenesis; Belongs to the FUN14 family

Top 10 interactors (score): YBR053C (0.909); ATG1 (0.9); CKA1 (0.9); CKA2 (0.9); CKB2 (0.9); ATG8 (0.81); UIP4 (0.809); GSP2 (0.74); RFS1 (0.735); OM45 (0.727); GUP1 (0.65); SYN8 (0.634); ATG5 (0.6); ATG12 (0.6); YRO2 (0.57); LYS20 (0.526); BFR2 (0.495); MDM10 (0.45); INA1 (0.402); HCA4 (0.4)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005295.1:122026-122622:+ gene-YAL008W_AKU4011 rna-NM_001178153.1_AKU4011 cds-NP_009394.1_AKU4011 99.8 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000070.1:108976-109572:+ gene-YAL008W_BG1 rna-NM_001178153.1_BG1 cds-NP_009394.1_BG1 98.9 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005503.1:136899-137495:+ gene-YAL008W_Bruggeman rna-NM_001178153.1_Bruggeman cds-NP_009394.1_Bruggeman 98.8 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005519.1:123236-123832:+ gene-YAL008W_CAT1 rna-NM_001178153.1_CAT1 cds-NP_009394.1_CAT1 98.9 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005359.1:135038-135634:+ gene-YAL008W_CBS1585 rna-NM_001178153.1_CBS1585 cds-NP_009394.1_CBS1585 99.3 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005343.1:135316-135912:+ gene-YAL008W_CBS436 rna-NM_001178153.1_CBS436 cds-NP_009394.1_CBS436 98.9 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005338.1:748132-748728:+ gene-YAL008W_CBS6412 rna-NM_001178153.1_CBS6412 cds-NP_009394.1_CBS6412 99.8 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005311.1:133308-133904:+ gene-YAL008W_CBS6413 rna-NM_001178153.1_CBS6413 cds-NP_009394.1_CBS6413 99.8 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001522.1:137074-137670:+ gene-YAL008W_CENPK1137D rna-NM_001178153.1_CENPK1137D cds-NP_009394.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005471.1:123445-124041:+ gene-YAL008W_EthanolRed rna-NM_001178153.1_EthanolRed cds-NP_009394.1_EthanolRed 99.8 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005535.1:138072-138668:+ gene-YAL008W_FaliES1 rna-NM_001178153.1_FaliES1 cds-NP_009394.1_FaliES1 99.4 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000084.1:109343-109939:+ gene-YAL008W_JAY291 rna-NM_001178153.1_JAY291 cds-NP_009394.1_JAY291 98.9 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005407.1:138052-138648:+ gene-YAL008W_MUCL30387 rna-NM_001178153.1_MUCL30387 cds-NP_009394.1_MUCL30387 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005439.1:135299-135895:+ gene-YAL008W_MUCL30388 rna-NM_001178153.1_MUCL30388 cds-NP_009394.1_MUCL30388 99.8 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005279.1:133820-134416:+ gene-YAL008W_MUCL39482 rna-NM_001178153.1_MUCL39482 cds-NP_009394.1_MUCL39482 99.8 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005423.1:136201-136797:+ gene-YAL008W_MUCL42920 rna-NM_001178153.1_MUCL42920 cds-NP_009394.1_MUCL42920 98.9 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011810.1:136791-137387:+ gene-YAL008W_NCIM3186 rna-NM_001178153.1_NCIM3186 cds-NP_009394.1_NCIM3186 92.2 100.0 Verified 1 1 0 False False False True False
NCYC1407 GCA_001738225.1 Sake Asia CM005263.1:121703-122299:+ gene-YAL008W_NCYC1407 rna-NM_001178153.1_NCYC1407 cds-NP_009394.1_NCYC1407 99.3 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994140.1:123631-124227:+ gene-YAL008W_PE2H3 rna-NM_001178153.1_PE2H3 cds-NP_009394.1_PE2H3 98.9 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999872.1:123350-123946:+ gene-YAL008W_PE2H4 rna-NM_001178153.1_PE2H4 cds-NP_009394.1_PE2H4 98.9 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001133.9:136914-137510:+ gene-YAL008W_S288C rna-NM_001178153.1_S288C cds-NP_009394.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000077.1:53835-54431:+ gene-YAL008W_SA1 rna-NM_001178153.1_SA1 cds-NP_009394.1_SA1 98.9 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005487.1:137564-138160:+ gene-YAL008W_ThermosaccDry rna-NM_001178153.1_ThermosaccDry cds-NP_009394.1_ThermosaccDry 99.8 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005455.1:138874-139470:+ gene-YAL008W_VR1 rna-NM_001178153.1_VR1 cds-NP_009394.1_VR1 98.9 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000002.1:109392-109988:+ gene-YAL008W_ZTW1 rna-NM_001178153.1_ZTW1 cds-NP_009394.1_ZTW1 99.3 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047487.1:126911-127516:+ gene-YAL008W_Sparadoxus rna-NM_001178153.1_Sparadoxus cds-NP_009394.1_Sparadoxus 86.6 100.0 Verified 1 1 1 False True False False False

Additional files