Gene name: FUN12
Reference locus (S288C): YAL035W
Gene biotype: protein_coding
Description: Translation initiation factor eIF5B; GTPase that promotes Met-tRNAiMet binding to ribosomes and ribosomal subunit joining; promotes GTP-dependent maturation of 18S rRNA by Nob1p; protein abundance increases in response to DNA replication stress; homolog of bacterial IF2
Top 10 interactors (score): PRT1 (0.999); RPS15 (0.999); RPS5 (0.999); RPL25 (0.999); RPS31 (0.999); TIF11 (0.999); RPS20 (0.999); SUI3 (0.999); SUI1 (0.999); ASC1 (0.999); RPL28 (0.999); RPG1 (0.999); RPS12 (0.999); RPS3 (0.999); PUF6 (0.999); NIP1 (0.999); TIF5 (0.999); RPS18B (0.998); RPS6B (0.998); RPS0B (0.998)
Homologues (species, bitscore): EIF5B (Homo sapiens, 714.9); Eif5b (Mus musculus, 717.6); eif5b (Danio rerio, 721.8); eif5b (Xenopus tropicalis, 660.6); eIF5B (Drosophila melanogaster, 713.4); iffb-1 (Caenorhabditis elegans, 646.7); AT1G76810 (Arabidopsis thaliana, 770.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005295.1:61557-64559:+ | gene-YAL035W_AKU4011 | rna-NM_001178180.1_AKU4011 | cds-NP_009365.1_AKU4011 | 99.0 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000070.1:48684-51689:+ | gene-YAL035W_BG1 | rna-NM_001178180.1_BG1 | cds-NP_009365.1_BG1 | 99.7 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005503.1:76435-79440:+ | gene-YAL035W_Bruggeman | rna-NM_001178180.1_Bruggeman | cds-NP_009365.1_Bruggeman | 99.5 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005519.1:62776-65787:+ | gene-YAL035W_CAT1 | rna-NM_001178180.1_CAT1 | cds-NP_009365.1_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005359.1:74574-77576:+ | gene-YAL035W_CBS1585 | rna-NM_001178180.1_CBS1585 | cds-NP_009365.1_CBS1585 | 99.0 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005343.1:74823-77828:+ | gene-YAL035W_CBS436 | rna-NM_001178180.1_CBS436 | cds-NP_009365.1_CBS436 | 99.7 | 99.9 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005327.1:60720-63722:+ | gene-YAL035W_CBS6412 | rna-NM_001178180.1_CBS6412 | cds-NP_009365.1_CBS6412 | 99.1 | 99.8 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005311.1:72839-75841:+ | gene-YAL035W_CBS6413 | rna-NM_001178180.1_CBS6413 | cds-NP_009365.1_CBS6413 | 99.0 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001522.1:76517-79525:+ | gene-YAL035W_CENPK1137D | rna-NM_001178180.1_CENPK1137D | cds-NP_009365.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005471.1:62965-65979:+ | gene-YAL035W_EthanolRed | rna-NM_001178180.1_EthanolRed | cds-NP_009365.1_EthanolRed | 98.6 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005535.1:77588-80602:+ | gene-YAL035W_FaliES1 | rna-NM_001178180.1_FaliES1 | cds-NP_009365.1_FaliES1 | 98.6 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000084.1:48868-51879:+ | gene-YAL035W_JAY291 | rna-NM_001178180.1_JAY291 | cds-NP_009365.1_JAY291 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005407.1:77523-80528:+ | gene-YAL035W_MUCL30387 | rna-NM_001178180.1_MUCL30387 | cds-NP_009365.1_MUCL30387 | 99.3 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005439.1:74073-77078:+ | gene-YAL035W_MUCL30388 | rna-NM_001178180.1_MUCL30388 | cds-NP_009365.1_MUCL30388 | 99.7 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005279.1:73360-76362:+ | gene-YAL035W_MUCL39482 | rna-NM_001178180.1_MUCL39482 | cds-NP_009365.1_MUCL39482 | 99.0 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005423.1:75731-78736:+ | gene-YAL035W_MUCL42920 | rna-NM_001178180.1_MUCL42920 | cds-NP_009365.1_MUCL42920 | 99.6 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011810.1:76304-79312:+ | gene-YAL035W_NCIM3186 | rna-NM_001178180.1_NCIM3186 | cds-NP_009365.1_NCIM3186 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005263.1:61238-64240:+ | gene-YAL035W_NCYC1407 | rna-NM_001178180.1_NCYC1407 | cds-NP_009365.1_NCYC1407 | 99.0 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994140.1:63138-66149:+ | gene-YAL035W_PE2H3 | rna-NM_001178180.1_PE2H3 | cds-NP_009365.1_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999872.1:62857-65868:+ | gene-YAL035W_PE2H4 | rna-NM_001178180.1_PE2H4 | cds-NP_009365.1_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001133.9:76427-79435:+ | gene-YAL035W_S288C | rna-NM_001178180.1_S288C | cds-NP_009365.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000059.1:5549-8560:+ | gene-YAL035W_SA1 | rna-NM_001178180.1_SA1 | cds-NP_009365.1_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005487.1:77106-80120:+ | gene-YAL035W_ThermosaccDry | rna-NM_001178180.1_ThermosaccDry | cds-NP_009365.1_ThermosaccDry | 98.6 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005455.1:78392-81403:+ | gene-YAL035W_VR1 | rna-NM_001178180.1_VR1 | cds-NP_009365.1_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000002.1:48926-51940:+ | gene-YAL035W_ZTW1 | rna-NM_001178180.1_ZTW1 | cds-NP_009365.1_ZTW1 | 98.5 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047487.1:66537-69509:+ | gene-YAL035W_Sparadoxus | rna-NM_001178180.1_Sparadoxus | cds-NP_009365.1_Sparadoxus | 90.4 | 98.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |