Gene name: FUM1
Reference locus (S288C): YPL262W
Gene biotype: protein_coding
Description: Fumarate hydratase, mitochondrial; Fumarase; converts fumaric acid to L-malic acid in the TCA cycle; cytosolic and mitochondrial distribution determined by the N-terminal targeting sequence, protein conformation, and status of glyoxylate shunt; phosphorylated in mitochondria; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily
Top 10 interactors (score): MDH1 (0.999); ACO1 (0.999); KGD1 (0.998); MDH3 (0.997); SDH3 (0.996); MDH2 (0.995); IDH2 (0.994); SDH4 (0.994); CIT1 (0.994); TPI1 (0.994); LSC1 (0.991); SDH2 (0.99); KGD2 (0.988); CIT3 (0.987); CIT2 (0.986); MAE1 (0.986); MLS1 (0.985); SDH1 (0.985); ALT1 (0.984); YJL045W (0.98)
Homologues (species, bitscore): FH (Homo sapiens, 648.7); Fh1 (Mus musculus, 652.5); fh (Danio rerio, 636.0); FH (Xenopus tropicalis, 597.8); l(1)G0255 (Drosophila melanogaster, 615.1); fum-1 (Caenorhabditis elegans, 630.2); FUM1 (Arabidopsis thaliana, 664.5)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005310.1:31636-33102:+ | gene-YPL262W_AKU4011 | rna-NM_001184076.1_AKU4011 | cds-NP_015061.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000185.1:7690-9156:- | gene-YPL262W_BG1 | rna-NM_001184076.1_BG1 | cds-NP_015061.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005518.1:48888-50354:+ | gene-YPL262W_Bruggeman | rna-NM_001184076.1_Bruggeman | cds-NP_015061.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005534.1:46838-48304:+ | gene-YPL262W_CAT1 | rna-NM_001184076.1_CAT1 | cds-NP_015061.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005374.1:35345-36811:+ | gene-YPL262W_CBS1585 | rna-NM_001184076.1_CBS1585 | cds-NP_015061.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005358.1:43738-45204:+ | gene-YPL262W_CBS436 | rna-NM_001184076.1_CBS436 | cds-NP_015061.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005342.1:40249-41715:+ | gene-YPL262W_CBS6412 | rna-NM_001184076.1_CBS6412 | cds-NP_015061.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005326.1:31496-32962:+ | gene-YPL262W_CBS6413 | rna-NM_001184076.1_CBS6413 | cds-NP_015061.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001537.1:47285-48751:+ | gene-YPL262W_CENPK1137D | rna-NM_001184076.1_CENPK1137D | cds-NP_015061.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:30679-32145:+ | gene-YPL262W_EthanolRed | rna-NM_001184076.1_EthanolRed | cds-NP_015061.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005550.1:31027-32493:+ | gene-YPL262W_FaliES1 | rna-NM_001184076.1_FaliES1 | cds-NP_015061.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000190.1:7604-9070:- | gene-YPL262W_JAY291 | rna-NM_001184076.1_JAY291 | cds-NP_015061.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005422.1:48145-49611:+ | gene-YPL262W_MUCL30387 | rna-NM_001184076.1_MUCL30387 | cds-NP_015061.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005454.1:46349-47815:+ | gene-YPL262W_MUCL30388 | rna-NM_001184076.1_MUCL30388 | cds-NP_015061.1_MUCL30388 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005294.1:28475-29941:+ | gene-YPL262W_MUCL39482 | rna-NM_001184076.1_MUCL39482 | cds-NP_015061.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005438.1:40638-42104:+ | gene-YPL262W_MUCL42920 | rna-NM_001184076.1_MUCL42920 | cds-NP_015061.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011825.1:47319-48785:+ | gene-YPL262W_NCIM3186 | rna-NM_001184076.1_NCIM3186 | cds-NP_015061.1_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005278.1:34921-36387:+ | gene-YPL262W_NCYC1407 | rna-NM_001184076.1_NCYC1407 | cds-NP_015061.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994155.1:38565-40031:+ | gene-YPL262W_PE2H3 | rna-NM_001184076.1_PE2H3 | cds-NP_015061.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999887.1:38551-40017:+ | gene-YPL262W_PE2H4 | rna-NM_001184076.1_PE2H4 | cds-NP_015061.1_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001148.4:47336-48802:+ | gene-YPL262W_S288C | rna-NM_001184076.1_S288C | cds-NP_015061.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000104.1:7727-9193:- | gene-YPL262W_SA1 | rna-NM_001184076.1_SA1 | cds-NP_015061.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005502.1:31028-32494:+ | gene-YPL262W_ThermosaccDry | rna-NM_001184076.1_ThermosaccDry | cds-NP_015061.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:277428-278894:+ | gene-YPL262W_VR1 | rna-NM_001184076.1_VR1 | cds-NP_015061.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000033.1:37146-38612:+ | gene-YPL262W_ZTW1 | rna-NM_001184076.1_ZTW1 | cds-NP_015061.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047502.1:38936-40402:+ | gene-YPL262W_Sparadoxus | rna-NM_001184076.1_Sparadoxus | cds-NP_015061.1_Sparadoxus | 90.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |