Gene name: FRS2
Reference locus (S288C): YFL022C
Gene biotype: protein_coding
Description: Alpha subunit of cytoplasmic phenylalanyl-tRNA synthetase; forms a tetramer with Frs1p to form active enzyme; evolutionarily distant from mitochondrial phenylalanyl-tRNA synthetase based on protein sequence, but substrate binding is similar; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily
Top 10 interactors (score): FRS1 (0.999); HTS1 (0.98); SEC4 (0.977); TYS1 (0.975); DED81 (0.971); VAS1 (0.968); KRS1 (0.955); THS1 (0.929); ILS1 (0.909); SES1 (0.908); ARO2 (0.902); MSF1 (0.894); GRS1 (0.871); WRS1 (0.864); GLN4 (0.843); FMT1 (0.835); MSK1 (0.833); ENP1 (0.824); DPS1 (0.819); YDR341C (0.808)
Homologues (species, bitscore): FARSA (Homo sapiens, 471.9); Farsa (Mus musculus, 469.5); farsa (Danio rerio, 484.2); farsa (Xenopus tropicalis, 483.0); CG2263 (Drosophila melanogaster, 477.6); fars-1 (Caenorhabditis elegans, 489.6); AT4G39280 (Arabidopsis thaliana, 470.3)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005300.1:89940-91451:- | gene-YFL022C_AKU4011 | rna-NM_001179944.2_AKU4011 | cds-NP_116631.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000199.1:4188-5699:+ | gene-YFL022C_BG1 | rna-NM_001179944.2_BG1 | cds-NP_116631.1_BG1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005508.1:88806-90317:- | gene-YFL022C_Bruggeman | rna-NM_001179944.2_Bruggeman | cds-NP_116631.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005524.1:94224-95735:- | gene-YFL022C_CAT1 | rna-NM_001179944.2_CAT1 | cds-NP_116631.1_CAT1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005364.1:90748-92259:- | gene-YFL022C_CBS1585 | rna-NM_001179944.2_CBS1585 | cds-NP_116631.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005348.1:64229-65740:- | gene-YFL022C_CBS436 | rna-NM_001179944.2_CBS436 | cds-NP_116631.1_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005332.1:90482-91993:- | gene-YFL022C_CBS6412 | rna-NM_001179944.2_CBS6412 | cds-NP_116631.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005316.1:93017-94528:- | gene-YFL022C_CBS6413 | rna-NM_001179944.2_CBS6413 | cds-NP_116631.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001527.1:90002-91513:- | gene-YFL022C_CENPK1137D | rna-NM_001179944.2_CENPK1137D | cds-NP_116631.1_CENPK1137D | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005476.1:88935-90446:- | gene-YFL022C_EthanolRed | rna-NM_001179944.2_EthanolRed | cds-NP_116631.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005540.1:90575-92086:- | gene-YFL022C_FaliES1 | rna-NM_001179944.2_FaliES1 | cds-NP_116631.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000448.1:98876-100387:- | gene-YFL022C_JAY291 | rna-NM_001179944.2_JAY291 | cds-NP_116631.1_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005412.1:90905-92416:- | gene-YFL022C_MUCL30387 | rna-NM_001179944.2_MUCL30387 | cds-NP_116631.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005444.1:88840-90351:- | gene-YFL022C_MUCL30388 | rna-NM_001179944.2_MUCL30388 | cds-NP_116631.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005284.1:89133-90644:- | gene-YFL022C_MUCL39482 | rna-NM_001179944.2_MUCL39482 | cds-NP_116631.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005428.1:88220-89731:- | gene-YFL022C_MUCL42920 | rna-NM_001179944.2_MUCL42920 | cds-NP_116631.1_MUCL42920 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011815.1:93498-95009:- | gene-YFL022C_NCIM3186 | rna-NM_001179944.2_NCIM3186 | cds-NP_116631.1_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005268.1:90222-91733:- | gene-YFL022C_NCYC1407 | rna-NM_001179944.2_NCYC1407 | cds-NP_116631.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994145.1:110071-111582:- | gene-YFL022C_PE2H3 | rna-NM_001179944.2_PE2H3 | cds-NP_116631.1_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999877.1:109619-111130:- | gene-YFL022C_PE2H4 | rna-NM_001179944.2_PE2H4 | cds-NP_116631.1_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001138.5:93499-95010:- | gene-YFL022C_S288C | rna-NM_001179944.2_S288C | cds-NP_116631.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000105.1:6235-7746:- | gene-YFL022C_SA1 | rna-NM_001179944.2_SA1 | cds-NP_116631.1_SA1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005492.1:89757-91268:- | gene-YFL022C_ThermosaccDry | rna-NM_001179944.2_ThermosaccDry | cds-NP_116631.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005460.1:98763-100274:- | gene-YFL022C_VR1 | rna-NM_001179944.2_VR1 | cds-NP_116631.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000013.1:20198-21709:- | gene-YFL022C_ZTW1 | rna-NM_001179944.2_ZTW1 | cds-NP_116631.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047492.1:113873-115384:- | gene-YFL022C_Sparadoxus | rna-NM_001179944.2_Sparadoxus | cds-NP_116631.1_Sparadoxus | 92.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |