Gene name: FRQ1
Reference locus (S288C): YDR373W
Gene biotype: protein_coding
Description: N-myristoylated calcium-binding protein; may have a role in intracellular signaling through its regulation of the phosphatidylinositol 4-kinase Pik1p; member of the recoverin/frequenin branch of the EF-hand superfamily; human NCS1 functionally complements the heat sensitivity of a frq1 ts mutant
Top 10 interactors (score): PIK1 (0.999); ATP2 (0.978); CMD1 (0.935); ARF1 (0.908); STT4 (0.875); BMH1 (0.87); BMH2 (0.868); SAC1 (0.817); LSB6 (0.802); YEF3 (0.719); PMR1 (0.694); SPC3 (0.693); TUB2 (0.679); SLY1 (0.671); INP54 (0.669); YPT31 (0.649); SYC1 (0.647); YSH1 (0.647); SAC6 (0.637); SEC7 (0.634)
Homologues (species, bitscore): NCS1 (Homo sapiens, 243.0); Ncs1 (Mus musculus, 243.0); ncs1a (Danio rerio, 245.7); ncs1 (Xenopus tropicalis, 243.0); Frq1 (Drosophila melanogaster, 228.4); ncs-1 (Caenorhabditis elegans, 238.0); SOS3 (Arabidopsis thaliana, 68.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:1162902-1163474:+ | gene-YDR373W_AKU4011 | rna-NM_001180681.3_AKU4011 | cds-NP_010661.3_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000039.1:41451-42023:+ | gene-YDR373W_BG1 | rna-NM_001180681.3_BG1 | cds-NP_010661.3_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:1193534-1194106:+ | gene-YDR373W_Bruggeman | rna-NM_001180681.3_Bruggeman | cds-NP_010661.3_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:1172145-1172717:+ | gene-YDR373W_CAT1 | rna-NM_001180681.3_CAT1 | cds-NP_010661.3_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:1157619-1158191:+ | gene-YDR373W_CBS1585 | rna-NM_001180681.3_CBS1585 | cds-NP_010661.3_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:1176202-1176774:+ | gene-YDR373W_CBS436 | rna-NM_001180681.3_CBS436 | cds-NP_010661.3_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:1153879-1154451:+ | gene-YDR373W_CBS6412 | rna-NM_001180681.3_CBS6412 | cds-NP_010661.3_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:1175769-1176341:+ | gene-YDR373W_CBS6413 | rna-NM_001180681.3_CBS6413 | cds-NP_010661.3_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:1221411-1221983:+ | gene-YDR373W_CENPK1137D | rna-NM_001180681.3_CENPK1137D | cds-NP_010661.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:1167303-1167875:+ | gene-YDR373W_EthanolRed | rna-NM_001180681.3_EthanolRed | cds-NP_010661.3_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:1170586-1171158:+ | gene-YDR373W_FaliES1 | rna-NM_001180681.3_FaliES1 | cds-NP_010661.3_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000057.1:19916-20488:- | gene-YDR373W_JAY291 | rna-NM_001180681.3_JAY291 | cds-NP_010661.3_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:1176852-1177424:+ | gene-YDR373W_MUCL30387 | rna-NM_001180681.3_MUCL30387 | cds-NP_010661.3_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:1159456-1160028:+ | gene-YDR373W_MUCL30388 | rna-NM_001180681.3_MUCL30388 | cds-NP_010661.3_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:1149153-1149725:+ | gene-YDR373W_MUCL39482 | rna-NM_001180681.3_MUCL39482 | cds-NP_010661.3_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:1091584-1092156:+ | gene-YDR373W_MUCL42920 | rna-NM_001180681.3_MUCL42920 | cds-NP_010661.3_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:1222682-1223254:+ | gene-YDR373W_NCIM3186 | rna-NM_001180681.3_NCIM3186 | cds-NP_010661.3_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:1162824-1163396:+ | gene-YDR373W_NCYC1407 | rna-NM_001180681.3_NCYC1407 | cds-NP_010661.3_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:1173252-1173824:+ | gene-YDR373W_PE2H3 | rna-NM_001180681.3_PE2H3 | cds-NP_010661.3_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:1178837-1179409:+ | gene-YDR373W_PE2H4 | rna-NM_001180681.3_PE2H4 | cds-NP_010661.3_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:1222759-1223331:+ | gene-YDR373W_S288C | rna-NM_001180681.3_S288C | cds-NP_010661.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000072.1:41532-42104:+ | gene-YDR373W_SA1 | rna-NM_001180681.3_SA1 | cds-NP_010661.3_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:1174867-1175439:+ | gene-YDR373W_ThermosaccDry | rna-NM_001180681.3_ThermosaccDry | cds-NP_010661.3_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:602215-602787:+ | gene-YDR373W_VR1 | rna-NM_001180681.3_VR1 | cds-NP_010661.3_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000008.1:217699-218271:+ | gene-YDR373W_ZTW1 | rna-NM_001180681.3_ZTW1 | cds-NP_010661.3_ZTW1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:1169379-1169951:+ | gene-YDR373W_Sparadoxus | rna-NM_001180681.3_Sparadoxus | cds-NP_010661.3_Sparadoxus | 91.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |