Gene name: FRK1
Reference locus (S288C): YPL141C
Gene biotype: protein_coding
Description: Fatty acyl-CoA synthetase and RNA processing-associated kinase 1; Protein kinase of unknown cellular role; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; interacts with rRNA transcription and ribosome biogenesis factors and the long chain fatty acyl-CoA synthetase Faa3p; FRK1 has a paralog, KIN4, that arose from the whole genome duplication
Top 10 interactors (score): VPS34 (0.911); VPS15 (0.907); VPS30 (0.907); SDS23 (0.798); SNF4 (0.798); SDS24 (0.798); GAL83 (0.792); SIP2 (0.792); MDG1 (0.792); SIP1 (0.792); CRP1 (0.792); TEM1 (0.784); YAL064W-B (0.708); BUB2 (0.679); PET20 (0.655); ATG1 (0.649); PRR1 (0.622); ATG13 (0.622); ATG11 (0.608); YKL222C (0.592)
Homologues (species, bitscore): BRSK1 (Homo sapiens, 220.3); Brsk1 (Mus musculus, 220.3); si:ch211-255p10.4 (Danio rerio, 221.1); prkaa1 (Xenopus tropicalis, 219.5); AMPKalpha (Drosophila melanogaster, 223.8); aak-2 (Caenorhabditis elegans, 213.4); KIN10 (Arabidopsis thaliana, 216.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005310.1:261118-263715:- | gene-YPL141C_AKU4011 | rna-NM_001183955.1_AKU4011 | cds-NP_015184.1_AKU4011 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000069.1:466804-469401:- | gene-YPL141C_BG1 | rna-NM_001183955.1_BG1 | cds-NP_015184.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005518.1:287113-289710:- | gene-YPL141C_Bruggeman | rna-NM_001183955.1_Bruggeman | cds-NP_015184.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005534.1:283791-286388:- | gene-YPL141C_CAT1 | rna-NM_001183955.1_CAT1 | cds-NP_015184.1_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005374.1:265184-267781:- | gene-YPL141C_CBS1585 | rna-NM_001183955.1_CBS1585 | cds-NP_015184.1_CBS1585 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005358.1:279855-282452:- | gene-YPL141C_CBS436 | rna-NM_001183955.1_CBS436 | cds-NP_015184.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005342.1:269859-272456:- | gene-YPL141C_CBS6412 | rna-NM_001183955.1_CBS6412 | cds-NP_015184.1_CBS6412 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005326.1:261823-264420:- | gene-YPL141C_CBS6413 | rna-NM_001183955.1_CBS6413 | cds-NP_015184.1_CBS6413 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001537.1:283366-285963:- | gene-YPL141C_CENPK1137D | rna-NM_001183955.1_CENPK1137D | cds-NP_015184.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:259807-262404:- | gene-YPL141C_EthanolRed | rna-NM_001183955.1_EthanolRed | cds-NP_015184.1_EthanolRed | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005550.1:267399-269996:- | gene-YPL141C_FaliES1 | rna-NM_001183955.1_FaliES1 | cds-NP_015184.1_FaliES1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000007.1:95852-98449:+ | gene-YPL141C_JAY291 | rna-NM_001183955.1_JAY291 | cds-NP_015184.1_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005422.1:278357-280954:- | gene-YPL141C_MUCL30387 | rna-NM_001183955.1_MUCL30387 | cds-NP_015184.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005454.1:276370-278967:- | gene-YPL141C_MUCL30388 | rna-NM_001183955.1_MUCL30388 | cds-NP_015184.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005294.1:258513-261110:- | gene-YPL141C_MUCL39482 | rna-NM_001183955.1_MUCL39482 | cds-NP_015184.1_MUCL39482 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005438.1:315754-318351:- | gene-YPL141C_MUCL42920 | rna-NM_001183955.1_MUCL42920 | cds-NP_015184.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011825.1:283447-286044:- | gene-YPL141C_NCIM3186 | rna-NM_001183955.1_NCIM3186 | cds-NP_015184.1_NCIM3186 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005278.1:264973-267570:- | gene-YPL141C_NCYC1407 | rna-NM_001183955.1_NCYC1407 | cds-NP_015184.1_NCYC1407 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994155.1:272419-275016:- | gene-YPL141C_PE2H3 | rna-NM_001183955.1_PE2H3 | cds-NP_015184.1_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999887.1:272054-274651:- | gene-YPL141C_PE2H4 | rna-NM_001183955.1_PE2H4 | cds-NP_015184.1_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001148.4:283464-286061:- | gene-YPL141C_S288C | rna-NM_001183955.1_S288C | cds-NP_015184.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000012.1:87622-90219:+ | gene-YPL141C_SA1 | rna-NM_001183955.1_SA1 | cds-NP_015184.1_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005502.1:267197-269794:- | gene-YPL141C_ThermosaccDry | rna-NM_001183955.1_ThermosaccDry | cds-NP_015184.1_ThermosaccDry | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005470.1:282175-284772:- | gene-YPL141C_VR1 | rna-NM_001183955.1_VR1 | cds-NP_015184.1_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000033.1:266527-269124:- | gene-YPL141C_ZTW1 | rna-NM_001183955.1_ZTW1 | cds-NP_015184.1_ZTW1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047502.1:268211-270805:- | gene-YPL141C_Sparadoxus | rna-NM_001183955.1_Sparadoxus | cds-NP_015184.1_Sparadoxus | 88.8 | 99.7 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |