Gene name: FRE4
Reference locus (S288C): YNR060W
Gene biotype: protein_coding
Description: Ferric reductase transmembrane component 4; Ferric reductase; reduces a specific subset of siderophore-bound iron prior to uptake by transporters; expression induced by low iron levels
Top 10 interactors (score): FRE8 (0.85); AFT1 (0.784); YHK8 (0.736); FET3 (0.719); CFT1 (0.699); FET4 (0.648); ECM15 (0.616); FIT2 (0.615); PRM6 (0.611); HMX1 (0.594); FIT3 (0.574); MAC1 (0.567); ARN2 (0.566); RTC4 (0.525); CIR1 (0.525); GRX7 (0.524); ARN1 (0.501); ANR2 (0.499); SIT1 (0.488); HBN1 (0.48)
Homologues (species, bitscore): DUOX2 (Homo sapiens, 54.7); Duox2 (Mus musculus, 57.0); duox-2 (Caenorhabditis elegans, 53.5); FRO8 (Arabidopsis thaliana, 79.3)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:210041-212200:- | gene-YNR060W_AKU4011 | rna-NM_001183237.1_AKU4011 | cds-NP_014458.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000155.1:631522-633681:+ | gene-YNR060W_BG1 | rna-NM_001183237.1_BG1 | cds-NP_014458.1_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005516.1:741682-743841:+ | gene-YNR060W_Bruggeman | rna-NM_001183237.1_Bruggeman | cds-NP_014458.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:777063-779222:+ | gene-YNR060W_CAT1 | rna-NM_001183237.1_CAT1 | cds-NP_014458.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005372.1:728838-730997:+ | gene-YNR060W_CBS1585 | rna-NM_001183237.1_CBS1585 | cds-NP_014458.1_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:791696-793855:+ | gene-YNR060W_CBS436 | rna-NM_001183237.1_CBS436 | cds-NP_014458.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005340.1:717820-719979:+ | gene-YNR060W_CBS6412 | rna-NM_001183237.1_CBS6412 | cds-NP_014458.1_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005324.1:719501-721660:+ | gene-YNR060W_CBS6413 | rna-NM_001183237.1_CBS6413 | cds-NP_014458.1_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001535.1:733586-735745:+ | gene-YNR060W_CENPK1137D | rna-NM_001183237.1_CENPK1137D | cds-NP_014458.1_CENPK1137D | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005484.1:724478-726637:+ | gene-YNR060W_EthanolRed | rna-NM_001183237.1_EthanolRed | cds-NP_014458.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005548.1:715670-717829:+ | gene-YNR060W_FaliES1 | rna-NM_001183237.1_FaliES1 | cds-NP_014458.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000005.1:9906-12065:- | gene-YNR060W_JAY291 | rna-NM_001183237.1_JAY291 | cds-NP_014458.1_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005420.1:739641-741800:+ | gene-YNR060W_MUCL30387 | rna-NM_001183237.1_MUCL30387 | cds-NP_014458.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005452.1:781248-783407:+ | gene-YNR060W_MUCL30388 | rna-NM_001183237.1_MUCL30388 | cds-NP_014458.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005292.1:720304-722463:+ | gene-YNR060W_MUCL39482 | rna-NM_001183237.1_MUCL39482 | cds-NP_014458.1_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005436.1:726697-728856:+ | gene-YNR060W_MUCL42920 | rna-NM_001183237.1_MUCL42920 | cds-NP_014458.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011823.1:739920-742079:+ | gene-YNR060W_NCIM3186 | rna-NM_001183237.1_NCIM3186 | cds-NP_014458.1_NCIM3186 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005276.1:722820-724979:+ | gene-YNR060W_NCYC1407 | rna-NM_001183237.1_NCYC1407 | cds-NP_014458.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994153.1:724371-726530:+ | gene-YNR060W_PE2H3 | rna-NM_001183237.1_PE2H3 | cds-NP_014458.1_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999885.1:725773-727932:+ | gene-YNR060W_PE2H4 | rna-NM_001183237.1_PE2H4 | cds-NP_014458.1_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001146.8:739951-742110:+ | gene-YNR060W_S288C | rna-NM_001183237.1_S288C | cds-NP_014458.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000087.1:30574-32669:- | gene-YNR060W_SA1 | rna-NM_001183237.1_SA1 | cds-NP_014458.1_SA1 | 91.6 | 95.3 | Unannotated | 1 | 1 | 0 | False | False | True | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005500.1:716013-718172:+ | gene-YNR060W_ThermosaccDry | rna-NM_001183237.1_ThermosaccDry | cds-NP_014458.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005468.1:759259-761418:+ | gene-YNR060W_VR1 | rna-NM_001183237.1_VR1 | cds-NP_014458.1_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000030.1:625780-627939:+ | gene-YNR060W_ZTW1 | rna-NM_001183237.1_ZTW1 | cds-NP_014458.1_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047500.1:729813-731972:+ | gene-YNR060W_Sparadoxus | rna-NM_001183237.1_Sparadoxus | cds-NP_014458.1_Sparadoxus | 91.6 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |