Gene name: FRE2
Reference locus (S288C): YKL220C
Gene biotype: protein_coding
Description: Ferric/cupric reductase transmembrane component 2; Ferric reductase and cupric reductase; reduces siderophore-bound iron and oxidized copper prior to uptake by transporters; expression induced by low iron levels but not by low copper levels; Belongs to the ferric reductase (FRE) family
Top 10 interactors (score): FRE8 (0.906); FET3 (0.905); FTR1 (0.815); AFT1 (0.812); MAC1 (0.781); CCC2 (0.764); FET4 (0.757); CTR2 (0.748); CTR3 (0.731); ARN1 (0.701); ARN2 (0.698); FIT3 (0.696); FIT2 (0.694); AFT2 (0.691); FRE1 (0.664); FTH1 (0.645); YKL223W (0.611); CIR1 (0.597); MCH2 (0.592); SIT1 (0.577)
Homologues (species, bitscore): FRO8 (Arabidopsis thaliana, 75.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000195.1:8245-10380:+ | gene-YKL220C_BG1 | rna-NM_001179785.1_BG1 | cds-NP_012702.1_BG1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005513.1:9839-11974:- | gene-YKL220C_Bruggeman | rna-NM_001179785.1_Bruggeman | cds-NP_012702.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005529.1:7761-9896:- | gene-YKL220C_CAT1 | rna-NM_001179785.1_CAT1 | cds-NP_012702.1_CAT1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005369.1:6926-9061:- | gene-YKL220C_CBS1585 | rna-NM_001179785.1_CBS1585 | cds-NP_012702.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005353.1:6654-8789:- | gene-YKL220C_CBS436 | rna-NM_001179785.1_CBS436 | cds-NP_012702.1_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005321.1:7641-9776:- | gene-YKL220C_CBS6413 | rna-NM_001179785.1_CBS6413 | cds-NP_012702.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001532.1:8933-11068:- | gene-YKL220C_CENPK1137D | rna-NM_001179785.1_CENPK1137D | cds-NP_012702.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005481.1:7280-9415:- | gene-YKL220C_EthanolRed | rna-NM_001179785.1_EthanolRed | cds-NP_012702.1_EthanolRed | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005545.1:6922-9057:- | gene-YKL220C_FaliES1 | rna-NM_001179785.1_FaliES1 | cds-NP_012702.1_FaliES1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000006.2:6604-8739:- | gene-YKL220C_JAY291 | rna-NM_001179785.1_JAY291 | cds-NP_012702.1_JAY291 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005417.1:9384-12255:- | gene-YKL220C_MUCL30387 | rna-NM_001179785.1_MUCL30387 | cds-NP_012702.1_MUCL30387 | 74.1 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005449.1:6974-9109:- | gene-YKL220C_MUCL30388 | rna-NM_001179785.1_MUCL30388 | cds-NP_012702.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005289.1:7005-9140:- | gene-YKL220C_MUCL39482 | rna-NM_001179785.1_MUCL39482 | cds-NP_012702.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005433.1:10757-12892:- | gene-YKL220C_MUCL42920 | rna-NM_001179785.1_MUCL42920 | cds-NP_012702.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011820.1:9080-11215:- | gene-YKL220C_NCIM3186 | rna-NM_001179785.1_NCIM3186 | cds-NP_012702.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005273.1:7039-9174:- | gene-YKL220C_NCYC1407 | rna-NM_001179785.1_NCYC1407 | cds-NP_012702.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994150.1:15221-17356:- | gene-YKL220C_PE2H3 | rna-NM_001179785.1_PE2H3 | cds-NP_012702.1_PE2H3 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999882.1:11425-13560:- | gene-YKL220C_PE2H4 | rna-NM_001179785.1_PE2H4 | cds-NP_012702.1_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001143.9:9091-11226:- | gene-YKL220C_S288C | rna-NM_001179785.1_S288C | cds-NP_012702.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000125.1:825-2960:+ | gene-YKL220C_SA1 | rna-NM_001179785.1_SA1 | cds-NP_012702.1_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005497.1:7659-9794:- | gene-YKL220C_ThermosaccDry | rna-NM_001179785.1_ThermosaccDry | cds-NP_012702.1_ThermosaccDry | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005465.1:6594-8729:- | gene-YKL220C_VR1 | rna-NM_001179785.1_VR1 | cds-NP_012702.1_VR1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000022.1:6603-8764:- | gene-YKL220C_ZTW1 | rna-NM_001179785.1_ZTW1 | cds-NP_012702.1_ZTW1 | 98.2 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047497.1:15893-18028:- | gene-YKL220C_Sparadoxus | rna-NM_001179785.1_Sparadoxus | cds-NP_012702.1_Sparadoxus | 89.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |