Gene name: FRE1
Reference locus (S288C): YLR214W
Gene biotype: protein_coding
Description: Ferric/cupric reductase transmembrane component 1; Ferric reductase and cupric reductase; reduces siderophore-bound iron and oxidized copper prior to uptake by transporters; expression induced by low copper and iron levels
Top 10 interactors (score): FET3 (0.969); FTR1 (0.928); MAC1 (0.922); CTR3 (0.922); FRE8 (0.905); AFT1 (0.893); CCC2 (0.838); AFT2 (0.812); FET4 (0.788); ARN1 (0.783); FET5 (0.754); FTH1 (0.753); CRS5 (0.75); CTR2 (0.743); SMF3 (0.733); SOD1 (0.731); HMX1 (0.723); CUP1-2 (0.719); SIT1 (0.718); ENB1 (0.717)
Homologues (species, bitscore): Cybb (Mus musculus, 50.8); NOX5 (Danio rerio, 50.1); FRO5 (Arabidopsis thaliana, 52.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:522710-524770:+ | gene-YLR214W_AKU4011 | rna-NM_001182101.1_AKU4011 | cds-NP_013315.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000177.1:79968-82028:+ | gene-YLR214W_BG1 | rna-NM_001182101.1_BG1 | cds-NP_013315.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:562937-564997:+ | gene-YLR214W_Bruggeman | rna-NM_001182101.1_Bruggeman | cds-NP_013315.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:562586-564646:+ | gene-YLR214W_CAT1 | rna-NM_001182101.1_CAT1 | cds-NP_013315.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:558202-560262:+ | gene-YLR214W_CBS1585 | rna-NM_001182101.1_CBS1585 | cds-NP_013315.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:548404-550464:+ | gene-YLR214W_CBS436 | rna-NM_001182101.1_CBS436 | cds-NP_013315.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:526764-528824:+ | gene-YLR214W_CBS6412 | rna-NM_001182101.1_CBS6412 | cds-NP_013315.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:558499-560559:+ | gene-YLR214W_CBS6413 | rna-NM_001182101.1_CBS6413 | cds-NP_013315.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:553207-555267:+ | gene-YLR214W_CENPK1137D | rna-NM_001182101.1_CENPK1137D | cds-NP_013315.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:522222-524282:+ | gene-YLR214W_EthanolRed | rna-NM_001182101.1_EthanolRed | cds-NP_013315.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:551149-553209:+ | gene-YLR214W_FaliES1 | rna-NM_001182101.1_FaliES1 | cds-NP_013315.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000004.1:78054-80114:+ | gene-YLR214W_JAY291 | rna-NM_001182101.1_JAY291 | cds-NP_013315.1_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:563798-565858:+ | gene-YLR214W_MUCL30387 | rna-NM_001182101.1_MUCL30387 | cds-NP_013315.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:567919-569979:+ | gene-YLR214W_MUCL30388 | rna-NM_001182101.1_MUCL30388 | cds-NP_013315.1_MUCL30388 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:559185-561245:+ | gene-YLR214W_MUCL39482 | rna-NM_001182101.1_MUCL39482 | cds-NP_013315.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:559685-561745:+ | gene-YLR214W_MUCL42920 | rna-NM_001182101.1_MUCL42920 | cds-NP_013315.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:568541-570601:+ | gene-YLR214W_NCIM3186 | rna-NM_001182101.1_NCIM3186 | cds-NP_013315.1_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:551604-553664:+ | gene-YLR214W_NCYC1407 | rna-NM_001182101.1_NCYC1407 | cds-NP_013315.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:555857-557917:+ | gene-YLR214W_PE2H3 | rna-NM_001182101.1_PE2H3 | cds-NP_013315.1_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:555601-557661:+ | gene-YLR214W_PE2H4 | rna-NM_001182101.1_PE2H4 | cds-NP_013315.1_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:568567-570627:+ | gene-YLR214W_S288C | rna-NM_001182101.1_S288C | cds-NP_013315.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000042.1:78105-80165:+ | gene-YLR214W_SA1 | rna-NM_001182101.1_SA1 | cds-NP_013315.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:553642-555702:+ | gene-YLR214W_ThermosaccDry | rna-NM_001182101.1_ThermosaccDry | cds-NP_013315.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:564991-567051:+ | gene-YLR214W_VR1 | rna-NM_001182101.1_VR1 | cds-NP_013315.1_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000024.1:77930-79990:+ | gene-YLR214W_ZTW1 | rna-NM_001182101.1_ZTW1 | cds-NP_013315.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:539767-541836:+ | gene-YLR214W_Sparadoxus | rna-NM_001182101.1_Sparadoxus | cds-NP_013315.1_Sparadoxus | 89.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |