Gene name: FPS1
Reference locus (S288C): YLL043W
Gene biotype: protein_coding
Description: Aquaglyceroporin related protein, other eukaryote; Glycerol uptake/efflux facilitator protein; Aquaglyceroporin, plasma membrane channel; involved in efflux of glycerol and xylitol, and in uptake of acetic acid, arsenite, and antimonite; key factor in maintaining redox balance by mediating passive diffusion of glycerol; phosphorylated by Hog1p MAPK under acetate stress; deletion improves xylose fermentation; regulated by Rgc1p and Ask10p, which are regulated by Hog1p phosphorylation under osmotic stress; phosphorylation by Ypk1p required to maintain an open state; Belongs to the MIP/aq [...]
Top 10 interactors (score): HOG1 (0.992); ASK10 (0.971); ERG20 (0.959); RGC1 (0.908); STL1 (0.907); SLT2 (0.89); ARR3 (0.875); SLN1 (0.843); SHO1 (0.819); GPP2 (0.813); SSK2 (0.791); AQY1 (0.782); GUT1 (0.776); YCF1 (0.764); GUT2 (0.75); HAA1 (0.745); SSK22 (0.745); GPP1 (0.744); PBS2 (0.744); AQY2 (0.721)
Homologues (species, bitscore): AQP9 (Homo sapiens, 124.8); Aqp9 (Mus musculus, 127.1); aqp9b (Danio rerio, 114.4); aqp9 (Xenopus tropicalis, 109.8); CG17664 (Drosophila melanogaster, 65.1); aqp-7 (Caenorhabditis elegans, 96.3); NIP4;2 (Arabidopsis thaliana, 68.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:37096-39111:+ | gene-YLL043W_AKU4011 | rna-NM_001181863.1_AKU4011 | cds-NP_013057.1_AKU4011 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000212.1:1052-3061:+ | gene-YLL043W_BG1 | rna-NM_001181863.1_BG1 | cds-NP_013057.1_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:46439-48448:+ | gene-YLL043W_Bruggeman | rna-NM_001181863.1_Bruggeman | cds-NP_013057.1_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:47968-49980:+ | gene-YLL043W_CAT1 | rna-NM_001181863.1_CAT1 | cds-NP_013057.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:45002-47017:+ | gene-YLL043W_CBS1585 | rna-NM_001181863.1_CBS1585 | cds-NP_013057.1_CBS1585 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:34995-37004:+ | gene-YLL043W_CBS436 | rna-NM_001181863.1_CBS436 | cds-NP_013057.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:44666-46681:+ | gene-YLL043W_CBS6412 | rna-NM_001181863.1_CBS6412 | cds-NP_013057.1_CBS6412 | 98.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:44803-46806:+ | gene-YLL043W_CBS6413 | rna-NM_001181863.1_CBS6413 | cds-NP_013057.1_CBS6413 | 98.8 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:34918-36927:+ | gene-YLL043W_CENPK1137D | rna-NM_001181863.1_CENPK1137D | cds-NP_013057.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:37728-39731:+ | gene-YLL043W_EthanolRed | rna-NM_001181863.1_EthanolRed | cds-NP_013057.1_EthanolRed | 98.8 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:37041-39044:+ | gene-YLL043W_FaliES1 | rna-NM_001181863.1_FaliES1 | cds-NP_013057.1_FaliES1 | 98.8 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000145.1:2040-4049:+ | gene-YLL043W_JAY291 | rna-NM_001181863.1_JAY291 | cds-NP_013057.1_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:44751-46760:+ | gene-YLL043W_MUCL30387 | rna-NM_001181863.1_MUCL30387 | cds-NP_013057.1_MUCL30387 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:48745-50754:+ | gene-YLL043W_MUCL30388 | rna-NM_001181863.1_MUCL30388 | cds-NP_013057.1_MUCL30388 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:45005-47020:+ | gene-YLL043W_MUCL39482 | rna-NM_001181863.1_MUCL39482 | cds-NP_013057.1_MUCL39482 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:45312-47321:+ | gene-YLL043W_MUCL42920 | rna-NM_001181863.1_MUCL42920 | cds-NP_013057.1_MUCL42920 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:49912-51921:+ | gene-YLL043W_NCIM3186 | rna-NM_001181863.1_NCIM3186 | cds-NP_013057.1_NCIM3186 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:36883-38886:+ | gene-YLL043W_NCYC1407 | rna-NM_001181863.1_NCYC1407 | cds-NP_013057.1_NCYC1407 | 98.9 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:43556-45565:+ | gene-YLL043W_PE2H3 | rna-NM_001181863.1_PE2H3 | cds-NP_013057.1_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:43362-45371:+ | gene-YLL043W_PE2H4 | rna-NM_001181863.1_PE2H4 | cds-NP_013057.1_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:49938-51947:+ | gene-YLL043W_S288C | rna-NM_001181863.1_S288C | cds-NP_013057.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000047.1:43229-45238:+ | gene-YLL043W_SA1 | rna-NM_001181863.1_SA1 | cds-NP_013057.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:37547-39550:+ | gene-YLL043W_ThermosaccDry | rna-NM_001181863.1_ThermosaccDry | cds-NP_013057.1_ThermosaccDry | 98.8 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:51132-53141:+ | gene-YLL043W_VR1 | rna-NM_001181863.1_VR1 | cds-NP_013057.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000023.1:36867-38876:+ | gene-YLL043W_ZTW1 | rna-NM_001181863.1_ZTW1 | cds-NP_013057.1_ZTW1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:45439-47460:+ | gene-YLL043W_Sparadoxus | rna-NM_001181863.1_Sparadoxus | cds-NP_013057.1_Sparadoxus | 91.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |