Gene name: FPR3
Reference locus (S288C): YML074C
Gene biotype: protein_coding
Description: FK506-binding nuclear protein; Nucleolar peptidyl-prolyl cis-trans isomerase (PPIase); FK506 binding protein; affects expression of multiple genes via its role in nucleosome assembly; phosphorylated by casein kinase II (Cka1p-Cka2p-Ckb1p-Ckb2p) and dephosphorylated by Ptp1p; PPIase domain acts as a transcriptional repressor when tethered to DNA by lexA, and repressor activity is dependent on PPIase activity; FPR3 has a paralog, FPR4, that arose from the whole genome duplication; Belongs to the FKBP-type PPIase family. FKBP3/4 subfamily
Top 10 interactors (score): FPR4 (0.999); RRS1 (0.952); NOP53 (0.949); RPF2 (0.943); EBP2 (0.943); NOG1 (0.939); BRX1 (0.935); CBF5 (0.924); SPB1 (0.922); NOP58 (0.919); RRB1 (0.919); CDC48 (0.918); SSM4 (0.918); NOP56 (0.918); UBX2 (0.918); ERB1 (0.917); RRP1 (0.916); HAS1 (0.916); NOP2 (0.913); NOC2 (0.912)
Homologues (species, bitscore): FKBP5 (Homo sapiens, 81.6); Fkbp1a (Mus musculus, 84.0); fkbp1aa (Danio rerio, 85.9); Fkbp1a (Xenopus tropicalis, 82.4); FK506-bp1 (Drosophila melanogaster, 153.7); fkb-2 (Caenorhabditis elegans, 79.7); FKBP53 (Arabidopsis thaliana, 106.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:113822-115057:- | gene-YML074C_AKU4011 | rna-NM_001182433.1_AKU4011 | cds-NP_013637.1_AKU4011 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000201.1:361064-362290:+ | gene-YML074C_BG1 | rna-NM_001182433.1_BG1 | cds-NP_013637.1_BG1 | 99.0 | 99.2 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:119991-121217:- | gene-YML074C_Bruggeman | rna-NM_001182433.1_Bruggeman | cds-NP_013637.1_Bruggeman | 98.9 | 99.2 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:121665-122891:- | gene-YML074C_CAT1 | rna-NM_001182433.1_CAT1 | cds-NP_013637.1_CAT1 | 98.9 | 99.2 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:113831-115066:- | gene-YML074C_CBS1585 | rna-NM_001182433.1_CBS1585 | cds-NP_013637.1_CBS1585 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:119759-120985:- | gene-YML074C_CBS436 | rna-NM_001182433.1_CBS436 | cds-NP_013637.1_CBS436 | 98.8 | 99.2 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:114539-115774:- | gene-YML074C_CBS6412 | rna-NM_001182433.1_CBS6412 | cds-NP_013637.1_CBS6412 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:113014-114249:- | gene-YML074C_CBS6413 | rna-NM_001182433.1_CBS6413 | cds-NP_013637.1_CBS6413 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:114809-116047:- | gene-YML074C_CENPK1137D | rna-NM_001182433.1_CENPK1137D | cds-NP_013637.1_CENPK1137D | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005483.1:114097-115332:- | gene-YML074C_EthanolRed | rna-NM_001182433.1_EthanolRed | cds-NP_013637.1_EthanolRed | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:114604-115839:- | gene-YML074C_FaliES1 | rna-NM_001182433.1_FaliES1 | cds-NP_013637.1_FaliES1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000366.1:41254-42480:+ | gene-YML074C_JAY291 | rna-NM_001182433.1_JAY291 | cds-NP_013637.1_JAY291 | 99.0 | 99.2 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:118515-119750:- | gene-YML074C_MUCL30387 | rna-NM_001182433.1_MUCL30387 | cds-NP_013637.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005451.1:121661-122887:- | gene-YML074C_MUCL30388 | rna-NM_001182433.1_MUCL30388 | cds-NP_013637.1_MUCL30388 | 98.9 | 99.2 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:113842-115077:- | gene-YML074C_MUCL39482 | rna-NM_001182433.1_MUCL39482 | cds-NP_013637.1_MUCL39482 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:118569-119810:- | gene-YML074C_MUCL42920 | rna-NM_001182433.1_MUCL42920 | cds-NP_013637.1_MUCL42920 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:120043-121278:- | gene-YML074C_NCIM3186 | rna-NM_001182433.1_NCIM3186 | cds-NP_013637.1_NCIM3186 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:114637-115872:- | gene-YML074C_NCYC1407 | rna-NM_001182433.1_NCYC1407 | cds-NP_013637.1_NCYC1407 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:119993-121219:- | gene-YML074C_PE2H3 | rna-NM_001182433.1_PE2H3 | cds-NP_013637.1_PE2H3 | 98.9 | 99.2 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:119936-121162:- | gene-YML074C_PE2H4 | rna-NM_001182433.1_PE2H4 | cds-NP_013637.1_PE2H4 | 99.0 | 99.2 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:120089-121324:- | gene-YML074C_S288C | rna-NM_001182433.1_S288C | cds-NP_013637.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000041.1:62922-64148:+ | gene-YML074C_SA1 | rna-NM_001182433.1_SA1 | cds-NP_013637.1_SA1 | 98.9 | 99.2 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:113896-115131:- | gene-YML074C_ThermosaccDry | rna-NM_001182433.1_ThermosaccDry | cds-NP_013637.1_ThermosaccDry | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:118284-119510:- | gene-YML074C_VR1 | rna-NM_001182433.1_VR1 | cds-NP_013637.1_VR1 | 99.1 | 99.2 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000027.1:93431-94666:- | gene-YML074C_ZTW1 | rna-NM_001182433.1_ZTW1 | cds-NP_013637.1_ZTW1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:124605-125834:- | gene-YML074C_Sparadoxus | rna-NM_001182433.1_Sparadoxus | cds-NP_013637.1_Sparadoxus | 90.5 | 98.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |