Gene name: FPR2
Reference locus (S288C): YDR519W
Gene biotype: protein_coding
Description: Membrane-bound peptidyl-prolyl cis-trans isomerase (PPIase); binds to the drugs FK506 and rapamycin; expression pattern suggests possible involvement in ER protein trafficking; relocalizes from nucleus to vacuole upon DNA replication stress; mutation is functionally complemented by human FKBP2
Top 10 interactors (score): FPR1 (0.976); CIR1 (0.964); ATX1 (0.964); ESS1 (0.916); CPR2 (0.914); CPR5 (0.907); KAR2 (0.905); CPR1 (0.902); EUG1 (0.894); CPR4 (0.859); LHS1 (0.852); PDI1 (0.824); ERD2 (0.776); IRE1 (0.76); ERO1 (0.756); CPR3 (0.736); ERP1 (0.73); CPR6 (0.722); SSU72 (0.717); SSP120 (0.71)
Homologues (species, bitscore): FKBP2 (Homo sapiens, 124.4); Fkbp2 (Mus musculus, 124.8); fkbp2 (Danio rerio, 133.3); fkbp2 (Xenopus tropicalis, 128.3); CG14715 (Drosophila melanogaster, 128.6); fkb-1 (Caenorhabditis elegans, 119.4); FKBP15-2 (Arabidopsis thaliana, 135.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:1420469-1420876:+ | gene-YDR519W_AKU4011 | rna-NM_001180827.3_AKU4011 | cds-NP_010807.3_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000073.1:62091-62498:+ | gene-YDR519W_BG1 | rna-NM_001180827.3_BG1 | cds-NP_010807.3_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:1451756-1452163:+ | gene-YDR519W_Bruggeman | rna-NM_001180827.3_Bruggeman | cds-NP_010807.3_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:1428927-1429334:+ | gene-YDR519W_CAT1 | rna-NM_001180827.3_CAT1 | cds-NP_010807.3_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:1415195-1415602:+ | gene-YDR519W_CBS1585 | rna-NM_001180827.3_CBS1585 | cds-NP_010807.3_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:1434402-1434809:+ | gene-YDR519W_CBS436 | rna-NM_001180827.3_CBS436 | cds-NP_010807.3_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:1410360-1410767:+ | gene-YDR519W_CBS6412 | rna-NM_001180827.3_CBS6412 | cds-NP_010807.3_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:1433857-1434264:+ | gene-YDR519W_CBS6413 | rna-NM_001180827.3_CBS6413 | cds-NP_010807.3_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:1479115-1479522:+ | gene-YDR519W_CENPK1137D | rna-NM_001180827.3_CENPK1137D | cds-NP_010807.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:1423728-1424135:+ | gene-YDR519W_EthanolRed | rna-NM_001180827.3_EthanolRed | cds-NP_010807.3_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:1427280-1427687:+ | gene-YDR519W_FaliES1 | rna-NM_001180827.3_FaliES1 | cds-NP_010807.3_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000026.1:125628-126036:+ | gene-YDR519W_JAY291 | rna-NM_001180827.3_JAY291 | cds-NP_010807.3_JAY291 | 99.7 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:1434846-1435253:+ | gene-YDR519W_MUCL30387 | rna-NM_001180827.3_MUCL30387 | cds-NP_010807.3_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:1416299-1416706:+ | gene-YDR519W_MUCL30388 | rna-NM_001180827.3_MUCL30388 | cds-NP_010807.3_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:1406693-1407100:+ | gene-YDR519W_MUCL39482 | rna-NM_001180827.3_MUCL39482 | cds-NP_010807.3_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:1349325-1349732:+ | gene-YDR519W_MUCL42920 | rna-NM_001180827.3_MUCL42920 | cds-NP_010807.3_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:1480348-1480755:+ | gene-YDR519W_NCIM3186 | rna-NM_001180827.3_NCIM3186 | cds-NP_010807.3_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:1419985-1420392:+ | gene-YDR519W_NCYC1407 | rna-NM_001180827.3_NCYC1407 | cds-NP_010807.3_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:1430897-1431304:+ | gene-YDR519W_PE2H3 | rna-NM_001180827.3_PE2H3 | cds-NP_010807.3_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:1436365-1436772:+ | gene-YDR519W_PE2H4 | rna-NM_001180827.3_PE2H4 | cds-NP_010807.3_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:1480425-1480832:+ | gene-YDR519W_S288C | rna-NM_001180827.3_S288C | cds-NP_010807.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000004.1:136280-136687:- | gene-YDR519W_SA1 | rna-NM_001180827.3_SA1 | cds-NP_010807.3_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:1431502-1431909:+ | gene-YDR519W_ThermosaccDry | rna-NM_001180827.3_ThermosaccDry | cds-NP_010807.3_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:1447272-1447679:+ | gene-YDR519W_VR1 | rna-NM_001180827.3_VR1 | cds-NP_010807.3_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000008.1:474143-474550:+ | gene-YDR519W_ZTW1 | rna-NM_001180827.3_ZTW1 | cds-NP_010807.3_ZTW1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:1440454-1440861:+ | gene-YDR519W_Sparadoxus | rna-NM_001180827.3_Sparadoxus | cds-NP_010807.3_Sparadoxus | 89.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |