Gene name: FPR1
Reference locus (S288C): YNL135C
Gene biotype: protein_coding
Description: FK506-binding protein 1; Peptidyl-prolyl cis-trans isomerase (PPIase); binds to the drugs FK506 and rapamycin; also binds to the nonhistone chromatin binding protein Hmo1p and may regulate its assembly or function; N-terminally propionylated in vivo; mutation is functionally complemented by human FKBP1A
Top 10 interactors (score): TOR2 (0.999); TOR1 (0.999); CPR1 (0.998); CNB1 (0.997); CNA1 (0.992); CMP2 (0.986); FPR2 (0.976); KOG1 (0.97); YNK1 (0.969); CPR3 (0.967); ACB1 (0.967); SCP1 (0.962); TFS1 (0.939); YLR179C (0.939); CPR2 (0.902); GIM5 (0.896); HOM3 (0.894); LST8 (0.893); ESS1 (0.893); RPL29 (0.884)
Homologues (species, bitscore): FKBP1A (Homo sapiens, 135.2); Fkbp1a (Mus musculus, 135.6); fkbp1aa (Danio rerio, 131.0); Fkbp1a (Xenopus tropicalis, 122.1); FK506-bp2 (Drosophila melanogaster, 139.8); fkb-2 (Caenorhabditis elegans, 125.6); ROF1 (Arabidopsis thaliana, 119.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005308.1:365567-365911:- | gene-YNL135C_AKU4011 | rna-NM_001182973.1_AKU4011 | cds-NP_014264.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000155.1:269559-269903:- | gene-YNL135C_BG1 | rna-NM_001182973.1_BG1 | cds-NP_014264.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005516.1:375665-376009:- | gene-YNL135C_Bruggeman | rna-NM_001182973.1_Bruggeman | cds-NP_014264.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:418860-419204:- | gene-YNL135C_CAT1 | rna-NM_001182973.1_CAT1 | cds-NP_014264.1_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005372.1:366186-366530:- | gene-YNL135C_CBS1585 | rna-NM_001182973.1_CBS1585 | cds-NP_014264.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:434581-434925:- | gene-YNL135C_CBS436 | rna-NM_001182973.1_CBS436 | cds-NP_014264.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005340.1:361640-361984:- | gene-YNL135C_CBS6412 | rna-NM_001182973.1_CBS6412 | cds-NP_014264.1_CBS6412 | 99.1 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005324.1:362604-362948:- | gene-YNL135C_CBS6413 | rna-NM_001182973.1_CBS6413 | cds-NP_014264.1_CBS6413 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001535.1:365734-366078:- | gene-YNL135C_CENPK1137D | rna-NM_001182973.1_CENPK1137D | cds-NP_014264.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005484.1:362558-362902:- | gene-YNL135C_EthanolRed | rna-NM_001182973.1_EthanolRed | cds-NP_014264.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005548.1:358460-358804:- | gene-YNL135C_FaliES1 | rna-NM_001182973.1_FaliES1 | cds-NP_014264.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000021.1:14840-15184:- | gene-YNL135C_JAY291 | rna-NM_001182973.1_JAY291 | cds-NP_014264.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005420.1:371680-372024:- | gene-YNL135C_MUCL30387 | rna-NM_001182973.1_MUCL30387 | cds-NP_014264.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005452.1:406797-407141:- | gene-YNL135C_MUCL30388 | rna-NM_001182973.1_MUCL30388 | cds-NP_014264.1_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005292.1:363466-363810:- | gene-YNL135C_MUCL39482 | rna-NM_001182973.1_MUCL39482 | cds-NP_014264.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005436.1:366461-366805:- | gene-YNL135C_MUCL42920 | rna-NM_001182973.1_MUCL42920 | cds-NP_014264.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011823.1:371851-372195:- | gene-YNL135C_NCIM3186 | rna-NM_001182973.1_NCIM3186 | cds-NP_014264.1_NCIM3186 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005276.1:365598-365942:- | gene-YNL135C_NCYC1407 | rna-NM_001182973.1_NCYC1407 | cds-NP_014264.1_NCYC1407 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994153.1:362597-362941:- | gene-YNL135C_PE2H3 | rna-NM_001182973.1_PE2H3 | cds-NP_014264.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999885.1:361985-362329:- | gene-YNL135C_PE2H4 | rna-NM_001182973.1_PE2H4 | cds-NP_014264.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001146.8:371882-372226:- | gene-YNL135C_S288C | rna-NM_001182973.1_S288C | cds-NP_014264.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000018.1:41287-41631:+ | gene-YNL135C_SA1 | rna-NM_001182973.1_SA1 | cds-NP_014264.1_SA1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005500.1:359314-359658:- | gene-YNL135C_ThermosaccDry | rna-NM_001182973.1_ThermosaccDry | cds-NP_014264.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005468.1:377977-378321:- | gene-YNL135C_VR1 | rna-NM_001182973.1_VR1 | cds-NP_014264.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000030.1:269147-269491:- | gene-YNL135C_ZTW1 | rna-NM_001182973.1_ZTW1 | cds-NP_014264.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047500.1:370108-370452:- | gene-YNL135C_Sparadoxus | rna-NM_001182973.1_Sparadoxus | cds-NP_014264.1_Sparadoxus | 97.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |