FOL3 (YMR113W)


Gene profile

Gene name: FOL3
Reference locus (S288C): YMR113W
Gene biotype: protein_coding

Description: Dihydrofolate synthetase, involved in folic acid biosynthesis; catalyzes conversion of dihydropteroate to dihydrofolate in folate coenzyme biosynthesis; FOL3 has a paralog, RMA1, that arose from the whole genome duplication

Top 10 interactors (score): FOL1 (0.993); DFR1 (0.979); FOL2 (0.964); RMA1 (0.954); CDC21 (0.947); MET7 (0.885); FAU1 (0.878); MET13 (0.855); SHM1 (0.854); MET12 (0.841); ABZ2 (0.809); TRP3 (0.77); YNL247W (0.724); TRP5 (0.711); ABZ1 (0.708); MSD1 (0.697); DCP1 (0.683); ALG13 (0.639); MIS1 (0.622); ALG14 (0.617)

Homologues (species, bitscore): FPGS (Homo sapiens, 129.4); Fpgs (Mus musculus, 124.8); fpgs (Danio rerio, 128.6); fpgs (Xenopus tropicalis, 119.8); CG2543 (Drosophila melanogaster, 102.4); F25B5.6 (Caenorhabditis elegans, 126.3); GLA1 (Arabidopsis thaliana, 134.0)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005307.1:533171-534454:+ gene-YMR113W_AKU4011 rna-NM_001182613.1_AKU4011 cds-NP_013831.1_AKU4011 99.6 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000201.1:8394-9677:- gene-YMR113W_BG1 rna-NM_001182613.1_BG1 cds-NP_013831.1_BG1 99.7 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005515.1:475357-476640:+ gene-YMR113W_Bruggeman rna-NM_001182613.1_Bruggeman cds-NP_013831.1_Bruggeman 99.7 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005531.1:476574-477857:+ gene-YMR113W_CAT1 rna-NM_001182613.1_CAT1 cds-NP_013831.1_CAT1 99.6 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005371.1:466614-467897:+ gene-YMR113W_CBS1585 rna-NM_001182613.1_CBS1585 cds-NP_013831.1_CBS1585 99.6 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005355.1:471530-472813:+ gene-YMR113W_CBS436 rna-NM_001182613.1_CBS436 cds-NP_013831.1_CBS436 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005339.1:579222-580505:+ gene-YMR113W_CBS6412 rna-NM_001182613.1_CBS6412 cds-NP_013831.1_CBS6412 99.6 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005323.1:465375-466658:+ gene-YMR113W_CBS6413 rna-NM_001182613.1_CBS6413 cds-NP_013831.1_CBS6413 99.6 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001534.1:489525-490808:+ gene-YMR113W_CENPK1137D rna-NM_001182613.1_CENPK1137D cds-NP_013831.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005483.1:465797-467080:+ gene-YMR113W_EthanolRed rna-NM_001182613.1_EthanolRed cds-NP_013831.1_EthanolRed 99.6 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005547.1:471118-472401:+ gene-YMR113W_FaliES1 rna-NM_001182613.1_FaliES1 cds-NP_013831.1_FaliES1 99.6 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000380.1:8273-9556:- gene-YMR113W_JAY291 rna-NM_001182613.1_JAY291 cds-NP_013831.1_JAY291 99.7 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005419.1:472277-473560:+ gene-YMR113W_MUCL30387 rna-NM_001182613.1_MUCL30387 cds-NP_013831.1_MUCL30387 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005451.1:476528-477811:+ gene-YMR113W_MUCL30388 rna-NM_001182613.1_MUCL30388 cds-NP_013831.1_MUCL30388 99.6 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005291.1:466415-467698:+ gene-YMR113W_MUCL39482 rna-NM_001182613.1_MUCL39482 cds-NP_013831.1_MUCL39482 99.6 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005435.1:473431-474714:+ gene-YMR113W_MUCL42920 rna-NM_001182613.1_MUCL42920 cds-NP_013831.1_MUCL42920 99.7 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011822.1:494953-496236:+ gene-YMR113W_NCIM3186 rna-NM_001182613.1_NCIM3186 cds-NP_013831.1_NCIM3186 99.2 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005275.1:466311-467594:+ gene-YMR113W_NCYC1407 rna-NM_001182613.1_NCYC1407 cds-NP_013831.1_NCYC1407 99.6 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994152.1:472127-473410:+ gene-YMR113W_PE2H3 rna-NM_001182613.1_PE2H3 cds-NP_013831.1_PE2H3 99.5 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999884.1:478222-479505:+ gene-YMR113W_PE2H4 rna-NM_001182613.1_PE2H4 cds-NP_013831.1_PE2H4 99.7 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001145.3:494999-496282:+ gene-YMR113W_S288C rna-NM_001182613.1_S288C cds-NP_013831.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000048.1:75326-76609:- gene-YMR113W_SA1 rna-NM_001182613.1_SA1 cds-NP_013831.1_SA1 99.6 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005499.1:466977-468260:+ gene-YMR113W_ThermosaccDry rna-NM_001182613.1_ThermosaccDry cds-NP_013831.1_ThermosaccDry 99.6 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005467.1:478713-479996:+ gene-YMR113W_VR1 rna-NM_001182613.1_VR1 cds-NP_013831.1_VR1 99.8 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000027.1:443021-444304:+ gene-YMR113W_ZTW1 rna-NM_001182613.1_ZTW1 cds-NP_013831.1_ZTW1 99.6 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047499.1:480026-481309:+ gene-YMR113W_Sparadoxus rna-NM_001182613.1_Sparadoxus cds-NP_013831.1_Sparadoxus 89.2 100.0 Verified 1 1 1 False True False False False

Additional files