FMO1 (YHR176W)


Gene profile

Gene name: FMO1
Reference locus (S288C): YHR176W
Gene biotype: protein_coding

Description: Flavin-containing monooxygenase; localized to the cytoplasmic face of the ER membrane; catalyzes oxidation of biological thiols to maintain the ER redox buffer ratio for correct folding of disulfide-bonded proteins

Top 10 interactors (score): COQ6 (0.97); COQ8 (0.898); CAT5 (0.888); COQ9 (0.882); YAH1 (0.812); COQ5 (0.799); COQ1 (0.793); COQ4 (0.779); HFD1 (0.768); COQ2 (0.758); GPD2 (0.749); ARH1 (0.695); PUF3 (0.687); AIF1 (0.683); COQ11 (0.659); RIB5 (0.659); LYS2 (0.658); COQ10 (0.646); FMN1 (0.618); PGA3 (0.618)

Homologues (species, bitscore): FMO6P (Homo sapiens, 134.4); Fmo5 (Mus musculus, 125.6); fmo5 (Danio rerio, 129.8); fmo5 (Xenopus tropicalis, 132.5); Fmo-2 (Drosophila melanogaster, 133.7); C46H11.2 (Caenorhabditis elegans, 151.4); AT5G07800 (Arabidopsis thaliana, 142.1)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005302.1:441314-442612:+ gene-YHR176W_AKU4011 rna-NM_001179307.3_AKU4011 cds-NP_012046.4_AKU4011 99.4 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000141.1:75119-76417:- gene-YHR176W_BG1 rna-NM_001179307.3_BG1 cds-NP_012046.4_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005510.1:448567-449865:+ gene-YHR176W_Bruggeman rna-NM_001179307.3_Bruggeman cds-NP_012046.4_Bruggeman 99.4 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005526.1:443968-445266:+ gene-YHR176W_CAT1 rna-NM_001179307.3_CAT1 cds-NP_012046.4_CAT1 99.9 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005366.1:440768-442066:+ gene-YHR176W_CBS1585 rna-NM_001179307.3_CBS1585 cds-NP_012046.4_CBS1585 99.4 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005350.1:438220-439518:+ gene-YHR176W_CBS436 rna-NM_001179307.3_CBS436 cds-NP_012046.4_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005334.1:440865-442163:+ gene-YHR176W_CBS6412 rna-NM_001179307.3_CBS6412 cds-NP_012046.4_CBS6412 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005318.1:441666-442964:+ gene-YHR176W_CBS6413 rna-NM_001179307.3_CBS6413 cds-NP_012046.4_CBS6413 99.4 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001529.1:447410-448708:+ gene-YHR176W_CENPK1137D rna-NM_001179307.3_CENPK1137D cds-NP_012046.4_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005478.1:499863-501161:+ gene-YHR176W_EthanolRed rna-NM_001179307.3_EthanolRed cds-NP_012046.4_EthanolRed 99.3 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005542.1:442307-443605:+ gene-YHR176W_FaliES1 rna-NM_001179307.3_FaliES1 cds-NP_012046.4_FaliES1 99.3 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000376.1:11173-12471:- gene-YHR176W_JAY291 rna-NM_001179307.3_JAY291 cds-NP_012046.4_JAY291 99.7 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005414.1:449640-450938:+ gene-YHR176W_MUCL30387 rna-NM_001179307.3_MUCL30387 cds-NP_012046.4_MUCL30387 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005446.1:449079-450377:+ gene-YHR176W_MUCL30388 rna-NM_001179307.3_MUCL30388 cds-NP_012046.4_MUCL30388 99.5 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005286.1:440679-441977:+ gene-YHR176W_MUCL39482 rna-NM_001179307.3_MUCL39482 cds-NP_012046.4_MUCL39482 99.4 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005430.1:447298-448596:+ gene-YHR176W_MUCL42920 rna-NM_001179307.3_MUCL42920 cds-NP_012046.4_MUCL42920 99.6 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011817.1:454111-455409:+ gene-YHR176W_NCIM3186 rna-NM_001179307.3_NCIM3186 cds-NP_012046.4_NCIM3186 99.2 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005270.1:443138-444436:+ gene-YHR176W_NCYC1407 rna-NM_001179307.3_NCYC1407 cds-NP_012046.4_NCYC1407 99.4 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994147.1:442289-443587:+ gene-YHR176W_PE2H3 rna-NM_001179307.3_PE2H3 cds-NP_012046.4_PE2H3 99.9 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999879.1:449716-451014:+ gene-YHR176W_PE2H4 rna-NM_001179307.3_PE2H4 cds-NP_012046.4_PE2H4 99.9 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001140.6:454229-455527:+ gene-YHR176W_S288C rna-NM_001179307.3_S288C cds-NP_012046.4_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000079.1:2047-3345:+ gene-YHR176W_SA1 rna-NM_001179307.3_SA1 cds-NP_012046.4_SA1 99.9 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005494.1:443390-444688:+ gene-YHR176W_ThermosaccDry rna-NM_001179307.3_ThermosaccDry cds-NP_012046.4_ThermosaccDry 99.3 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005462.1:451215-452513:+ gene-YHR176W_VR1 rna-NM_001179307.3_VR1 cds-NP_012046.4_VR1 99.8 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000017.1:433631-434929:+ gene-YHR176W_ZTW1 rna-NM_001179307.3_ZTW1 cds-NP_012046.4_ZTW1 99.4 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047494.1:439827-441125:+ gene-YHR176W_Sparadoxus rna-NM_001179307.3_Sparadoxus cds-NP_012046.4_Sparadoxus 88.9 100.0 Verified 1 1 1 False True False False False

Additional files