Gene name: FLX1
Reference locus (S288C): YIL134W
Gene biotype: protein_coding
Description: Mitochondrial FAD carrier protein FLX1; Mitochondrial flavin adenine dinucleotide transporter; FAD is a synthesis product of riboflavin; human homolog SLC25A32 is implicated in multiple acyl-CoA dehydrogenase deficiency (MADD) or glutaric aciduria type II (GAII), and can complement yeast null mutant
Top 10 interactors (score): FMN1 (0.954); FAD1 (0.947); SDH3 (0.916); SDH4 (0.916); SDH2 (0.916); YMR178W (0.908); TCM62 (0.82); SDH5 (0.82); LEU5 (0.793); COQ6 (0.786); LPD1 (0.786); PUF3 (0.765); SDH1 (0.751); FLC1 (0.748); MCH5 (0.717); HEM14 (0.717); COX15 (0.697); RBH2 (0.696); NDI1 (0.695); YFL040W (0.677)
Homologues (species, bitscore): SLC25A32 (Homo sapiens, 166.0); Slc25a32 (Mus musculus, 168.7); slc25a32b (Danio rerio, 172.2); slc25a32 (Xenopus tropicalis, 163.3); CG8026 (Drosophila melanogaster, 169.5); K01C8.7 (Caenorhabditis elegans, 138.3); FOLT1 (Arabidopsis thaliana, 138.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005303.1:98612-99547:+ | gene-YIL134W_AKU4011 | rna-NM_001179482.3_AKU4011 | cds-NP_012132.3_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000174.1:37814-38749:- | gene-YIL134W_BG1 | rna-NM_001179482.3_BG1 | cds-NP_012132.3_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005511.1:101370-102305:+ | gene-YIL134W_Bruggeman | rna-NM_001179482.3_Bruggeman | cds-NP_012132.3_Bruggeman | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005527.1:95182-96117:+ | gene-YIL134W_CAT1 | rna-NM_001179482.3_CAT1 | cds-NP_012132.3_CAT1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005367.1:98814-99749:+ | gene-YIL134W_CBS1585 | rna-NM_001179482.3_CBS1585 | cds-NP_012132.3_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005351.1:89954-90889:+ | gene-YIL134W_CBS436 | rna-NM_001179482.3_CBS436 | cds-NP_012132.3_CBS436 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005335.1:96344-97279:+ | gene-YIL134W_CBS6412 | rna-NM_001179482.3_CBS6412 | cds-NP_012132.3_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005319.1:90500-91435:+ | gene-YIL134W_CBS6413 | rna-NM_001179482.3_CBS6413 | cds-NP_012132.3_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001530.1:89102-90037:+ | gene-YIL134W_CENPK1137D | rna-NM_001179482.3_CENPK1137D | cds-NP_012132.3_CENPK1137D | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005479.1:84148-85083:+ | gene-YIL134W_EthanolRed | rna-NM_001179482.3_EthanolRed | cds-NP_012132.3_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005543.1:99951-100886:+ | gene-YIL134W_FaliES1 | rna-NM_001179482.3_FaliES1 | cds-NP_012132.3_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000319.1:7467-8402:- | gene-YIL134W_JAY291 | rna-NM_001179482.3_JAY291 | cds-NP_012132.3_JAY291 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005415.1:99130-100065:+ | gene-YIL134W_MUCL30387 | rna-NM_001179482.3_MUCL30387 | cds-NP_012132.3_MUCL30387 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005447.1:98810-99745:+ | gene-YIL134W_MUCL30388 | rna-NM_001179482.3_MUCL30388 | cds-NP_012132.3_MUCL30388 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005287.1:99742-100677:+ | gene-YIL134W_MUCL39482 | rna-NM_001179482.3_MUCL39482 | cds-NP_012132.3_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005431.1:102942-103877:+ | gene-YIL134W_MUCL42920 | rna-NM_001179482.3_MUCL42920 | cds-NP_012132.3_MUCL42920 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011818.1:97395-98330:+ | gene-YIL134W_NCIM3186 | rna-NM_001179482.3_NCIM3186 | cds-NP_012132.3_NCIM3186 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005271.1:103706-104641:+ | gene-YIL134W_NCYC1407 | rna-NM_001179482.3_NCYC1407 | cds-NP_012132.3_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994148.1:98330-99265:+ | gene-YIL134W_PE2H3 | rna-NM_001179482.3_PE2H3 | cds-NP_012132.3_PE2H3 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999880.1:92292-93227:+ | gene-YIL134W_PE2H4 | rna-NM_001179482.3_PE2H4 | cds-NP_012132.3_PE2H4 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001141.2:97395-98330:+ | gene-YIL134W_S288C | rna-NM_001179482.3_S288C | cds-NP_012132.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000050.1:75971-76906:+ | gene-YIL134W_SA1 | rna-NM_001179482.3_SA1 | cds-NP_012132.3_SA1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005495.1:98561-99496:+ | gene-YIL134W_ThermosaccDry | rna-NM_001179482.3_ThermosaccDry | cds-NP_012132.3_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005463.1:95719-96654:+ | gene-YIL134W_VR1 | rna-NM_001179482.3_VR1 | cds-NP_012132.3_VR1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000019.1:73542-74477:+ | gene-YIL134W_ZTW1 | rna-NM_001179482.3_ZTW1 | cds-NP_012132.3_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047495.1:91386-92321:+ | gene-YIL134W_Sparadoxus | rna-NM_001179482.3_Sparadoxus | cds-NP_012132.3_Sparadoxus | 89.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |