Gene name: FLR1
Reference locus (S288C): YBR008C
Gene biotype: protein_coding
Description: Fluconazole resistance protein 1; Plasma membrane transporter of the major facilitator superfamily; member of the 12-spanner drug:H(+) antiporter DHA1 family; involved in efflux of fluconazole, diazaborine, benomyl, methotrexate, and other drugs; expression induced in cells treated with the mycotoxin patulin; relocalizes from nucleus to plasma membrane upon DNA replication stress
Top 10 interactors (score): YAP1 (0.952); ATR1 (0.913); HOL1 (0.905); AAD16 (0.884); GTT2 (0.874); ERG11 (0.845); SNQ2 (0.838); YRR1 (0.824); PDR3 (0.81); PDR15 (0.809); PDR10 (0.796); HAL9 (0.792); PDR5 (0.783); YCF1 (0.776); YKL071W (0.764); AZR1 (0.749); FRM2 (0.747); PDR1 (0.746); OYE3 (0.726); YOR1 (0.726)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005296.1:240951-242597:- | gene-YBR008C_AKU4011 | rna-NM_001178356.1_AKU4011 | cds-NP_009562.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000179.1:231057-232703:- | gene-YBR008C_BG1 | rna-NM_001178356.1_BG1 | cds-NP_009562.1_BG1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005504.1:241656-243302:- | gene-YBR008C_Bruggeman | rna-NM_001178356.1_Bruggeman | cds-NP_009562.1_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005520.1:243935-245581:- | gene-YBR008C_CAT1 | rna-NM_001178356.1_CAT1 | cds-NP_009562.1_CAT1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005360.1:232988-234634:- | gene-YBR008C_CBS1585 | rna-NM_001178356.1_CBS1585 | cds-NP_009562.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005344.1:241229-242875:- | gene-YBR008C_CBS436 | rna-NM_001178356.1_CBS436 | cds-NP_009562.1_CBS436 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005328.1:331489-333135:- | gene-YBR008C_CBS6412 | rna-NM_001178356.1_CBS6412 | cds-NP_009562.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005312.1:238353-239999:- | gene-YBR008C_CBS6413 | rna-NM_001178356.1_CBS6413 | cds-NP_009562.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001523.1:252249-253895:- | gene-YBR008C_CENPK1137D | rna-NM_001178356.1_CENPK1137D | cds-NP_009562.1_CENPK1137D | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005472.1:367948-369594:- | gene-YBR008C_EthanolRed | rna-NM_001178356.1_EthanolRed | cds-NP_009562.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005536.1:256045-257691:- | gene-YBR008C_FaliES1 | rna-NM_001178356.1_FaliES1 | cds-NP_009562.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000048.1:39911-41557:+ | gene-YBR008C_JAY291 | rna-NM_001178356.1_JAY291 | cds-NP_009562.1_JAY291 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005408.1:242010-243656:- | gene-YBR008C_MUCL30387 | rna-NM_001178356.1_MUCL30387 | cds-NP_009562.1_MUCL30387 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005440.1:242510-244156:- | gene-YBR008C_MUCL30388 | rna-NM_001178356.1_MUCL30388 | cds-NP_009562.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005280.1:232970-234616:- | gene-YBR008C_MUCL39482 | rna-NM_001178356.1_MUCL39482 | cds-NP_009562.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005424.1:240409-242055:- | gene-YBR008C_MUCL42920 | rna-NM_001178356.1_MUCL42920 | cds-NP_009562.1_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011811.1:252360-254006:- | gene-YBR008C_NCIM3186 | rna-NM_001178356.1_NCIM3186 | cds-NP_009562.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005264.1:234146-235792:- | gene-YBR008C_NCYC1407 | rna-NM_001178356.1_NCYC1407 | cds-NP_009562.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994141.1:246303-247949:- | gene-YBR008C_PE2H3 | rna-NM_001178356.1_PE2H3 | cds-NP_009562.1_PE2H3 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999873.1:243970-245616:- | gene-YBR008C_PE2H4 | rna-NM_001178356.1_PE2H4 | cds-NP_009562.1_PE2H4 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001134.8:252563-254209:- | gene-YBR008C_S288C | rna-NM_001178356.1_S288C | cds-NP_009562.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000037.1:48564-50210:+ | gene-YBR008C_SA1 | rna-NM_001178356.1_SA1 | cds-NP_009562.1_SA1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005488.1:255754-257400:- | gene-YBR008C_ThermosaccDry | rna-NM_001178356.1_ThermosaccDry | cds-NP_009562.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005456.1:237647-239293:- | gene-YBR008C_VR1 | rna-NM_001178356.1_VR1 | cds-NP_009562.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000003.1:231738-233384:- | gene-YBR008C_ZTW1 | rna-NM_001178356.1_ZTW1 | cds-NP_009562.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047488.1:267492-269138:- | gene-YBR008C_Sparadoxus | rna-NM_001178356.1_Sparadoxus | cds-NP_009562.1_Sparadoxus | 90.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |