Gene name: FLO11
Reference locus (S288C): YIR019C
Gene biotype: protein_coding
Description: Flocculation protein FLO11; GPI-anchored cell surface glycoprotein (flocculin); required for pseudohyphal and invasive growth, flocculation, and biofilm formation; major determinant of colony morphology; transcription regulated by the MAPK pathway (Ste12p and Tec1p) and the cAMP pathway (Flo8p); required for formation of fibrous interconnections between cells of a wild strain; role in co-flocculation with other yeast species; cleaved and shed from cells, contributing to their surface properties; Belongs to the flocculin family. Highly divergent
Top 10 interactors (score): FLO10 (0.958); SFL1 (0.945); FLO5 (0.941); FLO1 (0.941); MSS11 (0.934); FLO9 (0.919); STE12 (0.919); TEC1 (0.896); FLO8 (0.888); MSB2 (0.819); PHD1 (0.813); SOK2 (0.787); KSS1 (0.767); TPK2 (0.767); NRG1 (0.753); NRG2 (0.75); IME1 (0.748); MSN1 (0.748); FIG2 (0.746); MFG1 (0.746)
Homologues (species, bitscore): MACF1 (Homo sapiens, 56.2); syne2b (Danio rerio, 64.3); ENSXETP00000022817 (Xenopus tropicalis, 81.3); shot (Drosophila melanogaster, 137.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005303.1:388865-391850:- | gene-YIR019C_AKU4011 | rna-NM_001179541.3_AKU4011 | cds-NP_012284.3_AKU4011 | 69.0 | 71.6 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000072.1:34999-37694:+ | gene-YIR019C_BG1 | rna-NM_001179541.3_BG1 | cds-NP_012284.3_BG1 | 64.4 | 65.6 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005511.1:393195-397267:- | gene-YIR019C_Bruggeman | rna-NM_001179541.3_Bruggeman | cds-NP_012284.3_Bruggeman | 79.1 | 91.4 | Unannotated | 1 | 1 | 0 | False | False | True | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005527.1:379925-383035:- | gene-YIR019C_CAT1 | rna-NM_001179541.3_CAT1 | cds-NP_012284.3_CAT1 | 70.7 | 74.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005367.1:388911-392831:- | gene-YIR019C_CBS1585 | rna-NM_001179541.3_CBS1585 | cds-NP_012284.3_CBS1585 | 77.1 | 87.8 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005351.1:381445-384849:- | gene-YIR019C_CBS436 | rna-NM_001179541.3_CBS436 | cds-NP_012284.3_CBS436 | 79.3 | 82.2 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005327.1:87999-91336:- | gene-YIR019C_CBS6412 | rna-NM_001179541.3_CBS6412 | cds-NP_012284.3_CBS6412 | 65.6 | 80.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005319.1:380990-383936:- | gene-YIR019C_CBS6413 | rna-NM_001179541.3_CBS6413 | cds-NP_012284.3_CBS6413 | 70.5 | 71.8 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001530.1:381613-385336:- | gene-YIR019C_CENPK1137D | rna-NM_001179541.3_CENPK1137D | cds-NP_012284.3_CENPK1137D | 60.7 | 90.7 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005479.1:371964-374805:- | gene-YIR019C_EthanolRed | rna-NM_001179541.3_EthanolRed | cds-NP_012284.3_EthanolRed | 65.9 | 68.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005543.1:390704-394633:- | gene-YIR019C_FaliES1 | rna-NM_001179541.3_FaliES1 | cds-NP_012284.3_FaliES1 | 79.0 | 88.0 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000009.1:1-1415:+ | gene-YIR019C_JAY291 | rna-NM_001179541.3_JAY291 | cds-NP_012284.3_JAY291 | 34.2 | 34.4 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005415.1:392071-397152:- | gene-YIR019C_MUCL30387 | rna-NM_001179541.3_MUCL30387 | cds-NP_012284.3_MUCL30387 | 72.2 | 97.0 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005447.1:388825-391755:- | gene-YIR019C_MUCL30388 | rna-NM_001179541.3_MUCL30388 | cds-NP_012284.3_MUCL30388 | 69.3 | 71.1 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005287.1:389539-392977:- | gene-YIR019C_MUCL39482 | rna-NM_001179541.3_MUCL39482 | cds-NP_012284.3_MUCL39482 | 75.8 | 81.5 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005431.1:393045-397276:- | gene-YIR019C_MUCL42920 | rna-NM_001179541.3_MUCL42920 | cds-NP_012284.3_MUCL42920 | 78.6 | 92.7 | Unannotated | 1 | 1 | 0 | False | False | True | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011818.1:389572-393675:- | gene-YIR019C_NCIM3186 | rna-NM_001179541.3_NCIM3186 | cds-NP_012284.3_NCIM3186 | 48.4 | 65.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005271.1:393763-396741:- | gene-YIR019C_NCYC1407 | rna-NM_001179541.3_NCYC1407 | cds-NP_012284.3_NCYC1407 | 64.9 | 69.9 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994148.1:383459-387622:- | gene-YIR019C_PE2H3 | rna-NM_001179541.3_PE2H3 | cds-NP_012284.3_PE2H3 | 79.6 | 93.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999880.1:378165-382328:- | gene-YIR019C_PE2H4 | rna-NM_001179541.3_PE2H4 | cds-NP_012284.3_PE2H4 | 79.6 | 93.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001141.2:389572-393675:- | gene-YIR019C_S288C | rna-NM_001179541.3_S288C | cds-NP_012284.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000066.1:64492-65653:- | gene-YIR019C_SA1 | rna-NM_001179541.3_SA1 | cds-NP_012284.3_SA1 | 28.0 | 28.3 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005495.1:388321-391241:- | gene-YIR019C_ThermosaccDry | rna-NM_001179541.3_ThermosaccDry | cds-NP_012284.3_ThermosaccDry | 67.7 | 70.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005463.1:384884-388855:- | gene-YIR019C_VR1 | rna-NM_001179541.3_VR1 | cds-NP_012284.3_VR1 | 76.9 | 89.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000019.1:362319-363705:- | gene-YIR019C_ZTW1 | rna-NM_001179541.3_ZTW1 | cds-NP_012284.3_ZTW1 | 33.5 | 33.7 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047495.1:383710-389154:- | gene-YIR019C_Sparadoxus | rna-NM_001179541.3_Sparadoxus | cds-NP_012284.3_Sparadoxus | 61.5 | 94.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |