Gene name: FIS1
Reference locus (S288C): YIL065C
Gene biotype: protein_coding
Description: Protein involved in mitochondrial fission and peroxisome abundance; may have a distinct role in tethering protein aggregates to mitochondria in order to retain them in the mother cell; required for localization of Dnm1p and Mdv1p during mitochondrial division; mediates ethanol-induced apoptosis and ethanol-induced mitochondrial fragmentation; Belongs to the FIS1 family
Top 10 interactors (score): DNM1 (0.999); MDV1 (0.999); CAF4 (0.999); PEX11 (0.998); FZO1 (0.996); MGM1 (0.988); TOM20 (0.973); PEX12 (0.961); VPS1 (0.959); PEX19 (0.959); PEX14 (0.956); UGO1 (0.946); PEX3 (0.944); PEX13 (0.943); GEM1 (0.941); PXA1 (0.911); PXA2 (0.909); MSP1 (0.906); HFD1 (0.905); SYM1 (0.904)
Homologues (species, bitscore): FIS1 (Homo sapiens, 68.6); Fis1 (Mus musculus, 67.8); FIS1 (Danio rerio, 76.3); fis1 (Xenopus tropicalis, 77.4); Fis1 (Drosophila melanogaster, 73.2); fis-2 (Caenorhabditis elegans, 62.4); BIGYIN (Arabidopsis thaliana, 53.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005303.1:237976-238443:- | gene-YIL065C_AKU4011 | rna-NM_001179415.3_AKU4011 | cds-NP_012199.3_AKU4011 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000164.1:99905-100372:- | gene-YIL065C_BG1 | rna-NM_001179415.3_BG1 | cds-NP_012199.3_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005511.1:243391-243858:- | gene-YIL065C_Bruggeman | rna-NM_001179415.3_Bruggeman | cds-NP_012199.3_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005527.1:233666-234133:- | gene-YIL065C_CAT1 | rna-NM_001179415.3_CAT1 | cds-NP_012199.3_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005367.1:237547-238014:- | gene-YIL065C_CBS1585 | rna-NM_001179415.3_CBS1585 | cds-NP_012199.3_CBS1585 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005351.1:233594-234061:- | gene-YIL065C_CBS436 | rna-NM_001179415.3_CBS436 | cds-NP_012199.3_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005335.1:234922-235389:- | gene-YIL065C_CBS6412 | rna-NM_001179415.3_CBS6412 | cds-NP_012199.3_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005319.1:229467-229934:- | gene-YIL065C_CBS6413 | rna-NM_001179415.3_CBS6413 | cds-NP_012199.3_CBS6413 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001530.1:233357-233824:- | gene-YIL065C_CENPK1137D | rna-NM_001179415.3_CENPK1137D | cds-NP_012199.3_CENPK1137D | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005479.1:222274-222741:- | gene-YIL065C_EthanolRed | rna-NM_001179415.3_EthanolRed | cds-NP_012199.3_EthanolRed | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005543.1:239177-239644:- | gene-YIL065C_FaliES1 | rna-NM_001179415.3_FaliES1 | cds-NP_012199.3_FaliES1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000365.1:58489-58956:+ | gene-YIL065C_JAY291 | rna-NM_001179415.3_JAY291 | cds-NP_012199.3_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005415.1:241611-242078:- | gene-YIL065C_MUCL30387 | rna-NM_001179415.3_MUCL30387 | cds-NP_012199.3_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005447.1:238216-238683:- | gene-YIL065C_MUCL30388 | rna-NM_001179415.3_MUCL30388 | cds-NP_012199.3_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005287.1:238393-238860:- | gene-YIL065C_MUCL39482 | rna-NM_001179415.3_MUCL39482 | cds-NP_012199.3_MUCL39482 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005431.1:241757-242224:- | gene-YIL065C_MUCL42920 | rna-NM_001179415.3_MUCL42920 | cds-NP_012199.3_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011818.1:241308-241775:- | gene-YIL065C_NCIM3186 | rna-NM_001179415.3_NCIM3186 | cds-NP_012199.3_NCIM3186 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005271.1:242669-243136:- | gene-YIL065C_NCYC1407 | rna-NM_001179415.3_NCYC1407 | cds-NP_012199.3_NCYC1407 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994148.1:236649-237116:- | gene-YIL065C_PE2H3 | rna-NM_001179415.3_PE2H3 | cds-NP_012199.3_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999880.1:231364-231831:- | gene-YIL065C_PE2H4 | rna-NM_001179415.3_PE2H4 | cds-NP_012199.3_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001141.2:241308-241775:- | gene-YIL065C_S288C | rna-NM_001179415.3_S288C | cds-NP_012199.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000031.1:84066-84533:+ | gene-YIL065C_SA1 | rna-NM_001179415.3_SA1 | cds-NP_012199.3_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005495.1:237840-238307:- | gene-YIL065C_ThermosaccDry | rna-NM_001179415.3_ThermosaccDry | cds-NP_012199.3_ThermosaccDry | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005463.1:235523-235990:- | gene-YIL065C_VR1 | rna-NM_001179415.3_VR1 | cds-NP_012199.3_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000019.1:212102-212569:- | gene-YIL065C_ZTW1 | rna-NM_001179415.3_ZTW1 | cds-NP_012199.3_ZTW1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047495.1:236189-236656:- | gene-YIL065C_Sparadoxus | rna-NM_001179415.3_Sparadoxus | cds-NP_012199.3_Sparadoxus | 91.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |