FET3 (YMR058W)


Gene profile

Gene name: FET3
Reference locus (S288C): YMR058W
Gene biotype: protein_coding

Description: Iron transport multicopper oxidase FET3; Ferro-O2-oxidoreductase; multicopper oxidase that oxidizes ferrous (Fe2+) to ferric iron (Fe3+) for subsequent cellular uptake by transmembrane permease Ftr1p; required for high-affinity iron uptake and involved in mediating resistance to copper ion toxicity, belongs to class of integral membrane multicopper oxidases; protein abundance increases in response to DNA replication stress

Top 10 interactors (score): FTR1 (0.999); FET4 (0.991); SIT1 (0.989); CCC2 (0.985); ARN1 (0.971); FRE1 (0.969); AFT1 (0.967); SMF3 (0.93); FTH1 (0.921); FRE2 (0.905); ATX1 (0.904); AFT2 (0.891); ENB1 (0.87); SOD1 (0.866); SMF1 (0.864); MRS4 (0.857); CTR3 (0.854); CTR2 (0.846); FIT2 (0.844); BOL2 (0.834)

Homologues (species, bitscore): laccase2 (Drosophila melanogaster, 145.2); F21D5.3 (Caenorhabditis elegans, 125.9); AT4G39830 (Arabidopsis thaliana, 211.8)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005307.1:426533-428443:+ gene-YMR058W_AKU4011 rna-NM_001182556.1_AKU4011 cds-NP_013774.1_AKU4011 99.4 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000201.1:114337-116247:- gene-YMR058W_BG1 rna-NM_001182556.1_BG1 cds-NP_013774.1_BG1 98.6 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005515.1:368703-370613:+ gene-YMR058W_Bruggeman rna-NM_001182556.1_Bruggeman cds-NP_013774.1_Bruggeman 99.4 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005531.1:369042-370952:+ gene-YMR058W_CAT1 rna-NM_001182556.1_CAT1 cds-NP_013774.1_CAT1 99.4 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005371.1:359476-361386:+ gene-YMR058W_CBS1585 rna-NM_001182556.1_CBS1585 cds-NP_013774.1_CBS1585 99.4 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005355.1:365035-366945:+ gene-YMR058W_CBS436 rna-NM_001182556.1_CBS436 cds-NP_013774.1_CBS436 99.3 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005339.1:472876-474786:+ gene-YMR058W_CBS6412 rna-NM_001182556.1_CBS6412 cds-NP_013774.1_CBS6412 99.4 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005323.1:358733-360643:+ gene-YMR058W_CBS6413 rna-NM_001182556.1_CBS6413 cds-NP_013774.1_CBS6413 99.4 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001534.1:382936-384846:+ gene-YMR058W_CENPK1137D rna-NM_001182556.1_CENPK1137D cds-NP_013774.1_CENPK1137D 99.4 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005483.1:359328-361238:+ gene-YMR058W_EthanolRed rna-NM_001182556.1_EthanolRed cds-NP_013774.1_EthanolRed 99.4 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005547.1:362497-364407:+ gene-YMR058W_FaliES1 rna-NM_001182556.1_FaliES1 cds-NP_013774.1_FaliES1 99.4 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000033.1:72534-74444:- gene-YMR058W_JAY291 rna-NM_001182556.1_JAY291 cds-NP_013774.1_JAY291 99.3 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005419.1:364445-366355:+ gene-YMR058W_MUCL30387 rna-NM_001182556.1_MUCL30387 cds-NP_013774.1_MUCL30387 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005451.1:369114-371024:+ gene-YMR058W_MUCL30388 rna-NM_001182556.1_MUCL30388 cds-NP_013774.1_MUCL30388 99.4 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005291.1:359764-361674:+ gene-YMR058W_MUCL39482 rna-NM_001182556.1_MUCL39482 cds-NP_013774.1_MUCL39482 99.4 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005435.1:366425-368335:+ gene-YMR058W_MUCL42920 rna-NM_001182556.1_MUCL42920 cds-NP_013774.1_MUCL42920 99.4 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011822.1:388776-390686:+ gene-YMR058W_NCIM3186 rna-NM_001182556.1_NCIM3186 cds-NP_013774.1_NCIM3186 99.2 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005275.1:359676-361586:+ gene-YMR058W_NCYC1407 rna-NM_001182556.1_NCYC1407 cds-NP_013774.1_NCYC1407 99.4 100.0 Verified 1 1 0 False False True False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994152.1:365631-367541:+ gene-YMR058W_PE2H3 rna-NM_001182556.1_PE2H3 cds-NP_013774.1_PE2H3 99.3 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999884.1:371726-373636:+ gene-YMR058W_PE2H4 rna-NM_001182556.1_PE2H4 cds-NP_013774.1_PE2H4 99.3 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001145.3:388822-390732:+ gene-YMR058W_S288C rna-NM_001182556.1_S288C cds-NP_013774.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000005.1:159413-161323:- gene-YMR058W_SA1 rna-NM_001182556.1_SA1 cds-NP_013774.1_SA1 99.0 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005499.1:360300-362210:+ gene-YMR058W_ThermosaccDry rna-NM_001182556.1_ThermosaccDry cds-NP_013774.1_ThermosaccDry 99.4 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005467.1:370576-372486:+ gene-YMR058W_VR1 rna-NM_001182556.1_VR1 cds-NP_013774.1_VR1 99.1 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000027.1:338581-340491:+ gene-YMR058W_ZTW1 rna-NM_001182556.1_ZTW1 cds-NP_013774.1_ZTW1 99.4 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047499.1:372161-374074:+ gene-YMR058W_Sparadoxus rna-NM_001182556.1_Sparadoxus cds-NP_013774.1_Sparadoxus 91.6 100.0 Verified 1 1 1 False True False False False

Additional files