FES1 (YBR101C)


Gene profile

Gene name: FES1
Reference locus (S288C): YBR101C
Gene biotype: protein_coding

Description: Hsp70 (Ssa1p) nucleotide exchange factor; required for the release of misfolded proteins from the Hsp70 system to the Ub-proteasome machinery for destruction; cytosolic homolog of Sil1p, which is the nucleotide exchange factor for BiP (Kar2p) in the endoplasmic reticulum; protein abundance increases in response to DNA replication stress

Top 10 interactors (score): SSE1 (0.998); SIS1 (0.997); STI1 (0.993); SSA1 (0.992); HSP104 (0.992); SSE2 (0.987); BTN2 (0.986); HSP82 (0.98); AHA1 (0.979); CPR6 (0.978); SNL1 (0.976); HSP78 (0.971); HSC82 (0.967); HSP42 (0.956); MBF1 (0.952); HUA1 (0.946); HSP26 (0.94); SSA2 (0.934); HCH1 (0.92); YDJ1 (0.919)

Homologues (species, bitscore): CG10973 (Drosophila melanogaster, 61.6); Fes1C (Arabidopsis thaliana, 63.5)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005296.1:426184-427056:- gene-YBR101C_AKU4011 rna-NM_001178449.3_AKU4011 cds-NP_009659.3_AKU4011 99.1 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000179.1:417225-418097:- gene-YBR101C_BG1 rna-NM_001178449.3_BG1 cds-NP_009659.3_BG1 99.3 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005504.1:427962-428834:- gene-YBR101C_Bruggeman rna-NM_001178449.3_Bruggeman cds-NP_009659.3_Bruggeman 99.7 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005520.1:430732-431604:- gene-YBR101C_CAT1 rna-NM_001178449.3_CAT1 cds-NP_009659.3_CAT1 99.3 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005360.1:418469-419341:- gene-YBR101C_CBS1585 rna-NM_001178449.3_CBS1585 cds-NP_009659.3_CBS1585 99.1 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005344.1:426591-427463:- gene-YBR101C_CBS436 rna-NM_001178449.3_CBS436 cds-NP_009659.3_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005328.1:516697-517569:- gene-YBR101C_CBS6412 rna-NM_001178449.3_CBS6412 cds-NP_009659.3_CBS6412 99.1 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005312.1:423608-424480:- gene-YBR101C_CBS6413 rna-NM_001178449.3_CBS6413 cds-NP_009659.3_CBS6413 99.1 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001523.1:435721-436593:- gene-YBR101C_CENPK1137D rna-NM_001178449.3_CENPK1137D cds-NP_009659.3_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005472.1:552978-553850:- gene-YBR101C_EthanolRed rna-NM_001178449.3_EthanolRed cds-NP_009659.3_EthanolRed 99.3 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005536.1:442261-443133:- gene-YBR101C_FaliES1 rna-NM_001178449.3_FaliES1 cds-NP_009659.3_FaliES1 99.3 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000312.1:13165-14037:- gene-YBR101C_JAY291 rna-NM_001178449.3_JAY291 cds-NP_009659.3_JAY291 99.3 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005408.1:429996-430868:- gene-YBR101C_MUCL30387 rna-NM_001178449.3_MUCL30387 cds-NP_009659.3_MUCL30387 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005440.1:428996-429868:- gene-YBR101C_MUCL30388 rna-NM_001178449.3_MUCL30388 cds-NP_009659.3_MUCL30388 99.8 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005280.1:416612-417484:- gene-YBR101C_MUCL39482 rna-NM_001178449.3_MUCL39482 cds-NP_009659.3_MUCL39482 99.1 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005424.1:425676-426548:- gene-YBR101C_MUCL42920 rna-NM_001178449.3_MUCL42920 cds-NP_009659.3_MUCL42920 100.0 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011811.1:443618-444490:- gene-YBR101C_NCIM3186 rna-NM_001178449.3_NCIM3186 cds-NP_009659.3_NCIM3186 99.3 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005264.1:419391-420263:- gene-YBR101C_NCYC1407 rna-NM_001178449.3_NCYC1407 cds-NP_009659.3_NCYC1407 99.1 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994141.1:432010-432882:- gene-YBR101C_PE2H3 rna-NM_001178449.3_PE2H3 cds-NP_009659.3_PE2H3 99.3 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999873.1:429686-430558:- gene-YBR101C_PE2H4 rna-NM_001178449.3_PE2H4 cds-NP_009659.3_PE2H4 99.3 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001134.8:443821-444693:- gene-YBR101C_S288C rna-NM_001178449.3_S288C cds-NP_009659.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000017.1:33016-33888:+ gene-YBR101C_SA1 rna-NM_001178449.3_SA1 cds-NP_009659.3_SA1 99.1 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005488.1:441268-442140:- gene-YBR101C_ThermosaccDry rna-NM_001178449.3_ThermosaccDry cds-NP_009659.3_ThermosaccDry 99.3 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005456.1:423271-424143:- gene-YBR101C_VR1 rna-NM_001178449.3_VR1 cds-NP_009659.3_VR1 99.3 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000003.1:416931-417803:- gene-YBR101C_ZTW1 rna-NM_001178449.3_ZTW1 cds-NP_009659.3_ZTW1 99.3 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047488.1:453811-454683:- gene-YBR101C_Sparadoxus rna-NM_001178449.3_Sparadoxus cds-NP_009659.3_Sparadoxus 91.8 100.0 Verified 1 1 1 False True False False False

Additional files