FDH1 (YOR388C)


Gene profile

Gene name: FDH1
Reference locus (S288C): YOR388C
Gene biotype: protein_coding

Description: NAD(+)-dependent formate dehydrogenase; may protect cells from exogenous formate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily

Top 10 interactors (score): YJL068C (0.99); FUM1 (0.926); MDH1 (0.916); MDH3 (0.912); BNA7 (0.9); DAL7 (0.886); MAE1 (0.884); MLS1 (0.864); PCK1 (0.849); MDH2 (0.847); PYC2 (0.838); PYC1 (0.808); SFA1 (0.782); PPS1 (0.777); SEI1 (0.747); CTA1 (0.734); ICL1 (0.727); AGX1 (0.712); ALT2 (0.687); FBA1 (0.66)

Homologues (species, bitscore): GRHPR (Homo sapiens, 105.9); Grhpr (Mus musculus, 110.2); grhpra (Danio rerio, 117.5); grhpr.2 (Xenopus tropicalis, 117.5); CG31674 (Drosophila melanogaster, 106.3); C31C9.2 (Caenorhabditis elegans, 99.0); FDH (Arabidopsis thaliana, 334.0)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005310.1:1992-3121:+ gene-YOR388C_AKU4011 rna-NM_001183808.1_AKU4011 cds-NP_015033.1_AKU4011 99.5 99.9 Unannotated 1 1 0 False False False True False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000197.1:9703-10834:- gene-YOR388C_BG1 rna-NM_001183808.1_BG1 cds-NP_015033.1_BG1 99.7 100.0 Unannotated 1 1 0 False False False True False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005518.1:14938-16316:+ gene-YOR388C_Bruggeman rna-NM_001183808.1_Bruggeman cds-NP_015033.1_Bruggeman 81.7 100.0 Unannotated 1 1 0 False False False True False
CAT1 GCA_001738705.1 Bioethanol South America CM005534.1:16714-17845:+ gene-YOR388C_CAT1 rna-NM_001183808.1_CAT1 cds-NP_015033.1_CAT1 99.7 100.0 Unannotated 1 1 0 False False False True False
CBS1585 GCA_001738375.1 Sake Asia CM005374.1:5742-6872:+ gene-YOR388C_CBS1585 rna-NM_001183808.1_CBS1585 cds-NP_015033.1_CBS1585 99.8 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005358.1:13358-14489:+ gene-YOR388C_CBS436 rna-NM_001183808.1_CBS436 cds-NP_015033.1_CBS436 99.7 100.0 Unannotated 1 1 0 False False False True False
CBS6412 GCA_001738345.1 Sake Asia CM005342.1:11206-12335:+ gene-YOR388C_CBS6412 rna-NM_001183808.1_CBS6412 cds-NP_015033.1_CBS6412 99.6 99.9 Unannotated 1 1 0 False False False True False
CBS6413 GCA_001738265.1 Sake Asia CM005325.1:1047254-1048384:- gene-YOR388C_CBS6413 rna-NM_001183808.1_CBS6413 cds-NP_015033.1_CBS6413 99.3 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001536.1:1071648-1072778:- gene-YOR388C_CENPK1137D rna-NM_001183808.1_CENPK1137D cds-NP_015033.1_CENPK1137D 99.8 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005485.1:1038203-1039332:- gene-YOR388C_EthanolRed rna-NM_001183808.1_EthanolRed cds-NP_015033.1_EthanolRed 99.4 99.9 Unannotated 1 1 0 False False False True False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005549.1:1040066-1041196:- gene-YOR388C_FaliES1 rna-NM_001183808.1_FaliES1 cds-NP_015033.1_FaliES1 99.8 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000242.1:1198-2328:+ gene-YOR388C_JAY291 rna-NM_001183808.1_JAY291 cds-NP_015033.1_JAY291 99.8 100.0 Verified 1 1 0 False False True False False
MUCL30387 GCA_001738515.1 Bread Europe CM005422.1:18074-19454:+ gene-YOR388C_MUCL30387 rna-NM_001183808.1_MUCL30387 cds-NP_015033.1_MUCL30387 81.6 100.0 Unannotated 1 1 0 False False False True False
MUCL30388 GCA_001738495.1 Bread Europe CM005454.1:16444-17226:+ gene-YOR388C_MUCL30388 rna-NM_001183808.1_MUCL30388 cds-NP_015033.1_MUCL30388 68.9 69.2 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005293.1:1049669-1050799:- gene-YOR388C_MUCL39482 rna-NM_001183808.1_MUCL39482 cds-NP_015033.1_MUCL39482 99.8 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005438.1:9835-11176:+ gene-YOR388C_MUCL42920 rna-NM_001183808.1_MUCL42920 cds-NP_015033.1_MUCL42920 79.1 96.6 Unannotated 1 1 0 False False False True False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011824.1:1071682-1072812:- gene-YOR388C_NCIM3186 rna-NM_001183808.1_NCIM3186 cds-NP_015033.1_NCIM3186 100.0 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005277.1:1051027-1052157:- gene-YOR388C_NCYC1407 rna-NM_001183808.1_NCYC1407 cds-NP_015033.1_NCYC1407 99.7 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994152.1:912426-913556:- gene-YOR388C_PE2H3 rna-NM_001183808.1_PE2H3 cds-NP_015033.1_PE2H3 99.9 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999884.1:908228-909358:- gene-YOR388C_PE2H4 rna-NM_001183808.1_PE2H4 cds-NP_015033.1_PE2H4 99.9 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001147.6:1071793-1072923:- gene-YOR388C_S288C rna-NM_001183808.1_S288C cds-NP_015033.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000123.1:8493-9623:+ gene-YOR388C_SA1 rna-NM_001183808.1_SA1 cds-NP_015033.1_SA1 99.9 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005501.1:1039248-1040377:- gene-YOR388C_ThermosaccDry rna-NM_001183808.1_ThermosaccDry cds-NP_015033.1_ThermosaccDry 99.7 99.9 Unannotated 1 1 0 False False False True False
VR1 GCA_001738595.1 Bioethanol South America CM005470.1:15735-16865:+ gene-YOR388C_VR1 rna-NM_001183808.1_VR1 cds-NP_015033.1_VR1 99.9 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000033.1:7739-8869:+ gene-YOR388C_ZTW1 rna-NM_001183808.1_ZTW1 cds-NP_015033.1_ZTW1 99.8 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047501.1:1046666-1047796:- gene-YOR388C_Sparadoxus rna-NM_001183808.1_Sparadoxus cds-NP_015033.1_Sparadoxus 91.4 100.0 Verified 1 1 1 False True False False False

Additional files