Gene name: FDC1
Reference locus (S288C): YDR539W
Gene biotype: protein_coding
Description: Ferulic acid decarboxylase, also active on p-coumaric acid; essential for decarboxylation of aromatic carboxylic acids to corresponding vinyl derivatives; co-overproduction of Pad1p and Fdc1p greatly increases cinnamic acid decarboxylase activity; structure implicates Glu285 as the general base in the nonoxidative decarboxylation reaction catalyzed by Fdc1p; homolog of E. coli UbiD; GFP-fusion protein localizes to cytoplasm
Top 10 interactors (score): PAD1 (0.99); COQ2 (0.739); IRC4 (0.692); ATF1 (0.671); RIM21 (0.618); GRC3 (0.612); ARO3 (0.612); COQ8 (0.598); HEM3 (0.582); VPS70 (0.573); AQY2 (0.572); TSR4 (0.572); AQY1 (0.571); HEM2 (0.526); UTP25 (0.525); RRP36 (0.524); COQ3 (0.509); TOP2 (0.505); HEM13 (0.485); HEM12 (0.481)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:1451687-1453198:+ | gene-YDR539W_AKU4011 | rna-NM_001180847.1_AKU4011 | cds-NP_010828.1_AKU4011 | 99.6 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000117.1:401-1912:- | gene-YDR539W_BG1 | rna-NM_001180847.1_BG1 | cds-NP_010828.1_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:1484506-1486018:+ | gene-YDR539W_Bruggeman | rna-NM_001180847.1_Bruggeman | cds-NP_010828.1_Bruggeman | 99.6 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:1460789-1462300:+ | gene-YDR539W_CAT1 | rna-NM_001180847.1_CAT1 | cds-NP_010828.1_CAT1 | 90.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:1446415-1447926:+ | gene-YDR539W_CBS1585 | rna-NM_001180847.1_CBS1585 | cds-NP_010828.1_CBS1585 | 99.6 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:1466071-1467582:+ | gene-YDR539W_CBS436 | rna-NM_001180847.1_CBS436 | cds-NP_010828.1_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:1441579-1443090:+ | gene-YDR539W_CBS6412 | rna-NM_001180847.1_CBS6412 | cds-NP_010828.1_CBS6412 | 99.6 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:1465076-1466587:+ | gene-YDR539W_CBS6413 | rna-NM_001180847.1_CBS6413 | cds-NP_010828.1_CBS6413 | 99.6 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:1510372-1511882:+ | gene-YDR539W_CENPK1137D | rna-NM_001180847.1_CENPK1137D | cds-NP_010828.1_CENPK1137D | 99.6 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:1455226-1456737:+ | gene-YDR539W_EthanolRed | rna-NM_001180847.1_EthanolRed | cds-NP_010828.1_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:1458980-1460491:+ | gene-YDR539W_FaliES1 | rna-NM_001180847.1_FaliES1 | cds-NP_010828.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000206.1:9580-11091:- | gene-YDR539W_JAY291 | rna-NM_001180847.1_JAY291 | cds-NP_010828.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:1466588-1468099:+ | gene-YDR539W_MUCL30387 | rna-NM_001180847.1_MUCL30387 | cds-NP_010828.1_MUCL30387 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:1447825-1449337:+ | gene-YDR539W_MUCL30388 | rna-NM_001180847.1_MUCL30388 | cds-NP_010828.1_MUCL30388 | 99.6 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:1437912-1439423:+ | gene-YDR539W_MUCL39482 | rna-NM_001180847.1_MUCL39482 | cds-NP_010828.1_MUCL39482 | 99.6 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:1380961-1382472:+ | gene-YDR539W_MUCL42920 | rna-NM_001180847.1_MUCL42920 | cds-NP_010828.1_MUCL42920 | 99.8 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:1512017-1513528:+ | gene-YDR539W_NCIM3186 | rna-NM_001180847.1_NCIM3186 | cds-NP_010828.1_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:1451414-1452925:+ | gene-YDR539W_NCYC1407 | rna-NM_001180847.1_NCYC1407 | cds-NP_010828.1_NCYC1407 | 99.6 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:1462350-1463861:+ | gene-YDR539W_PE2H3 | rna-NM_001180847.1_PE2H3 | cds-NP_010828.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:1467818-1469329:+ | gene-YDR539W_PE2H4 | rna-NM_001180847.1_PE2H4 | cds-NP_010828.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:1512094-1513605:+ | gene-YDR539W_S288C | rna-NM_001180847.1_S288C | cds-NP_010828.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000004.1:103711-105222:- | gene-YDR539W_SA1 | rna-NM_001180847.1_SA1 | cds-NP_010828.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:1463286-1464797:+ | gene-YDR539W_ThermosaccDry | rna-NM_001180847.1_ThermosaccDry | cds-NP_010828.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:1478986-1480497:+ | gene-YDR539W_VR1 | rna-NM_001180847.1_VR1 | cds-NP_010828.1_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000008.1:505062-506574:+ | gene-YDR539W_ZTW1 | rna-NM_001180847.1_ZTW1 | cds-NP_010828.1_ZTW1 | 99.6 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:1471573-1473084:+ | gene-YDR539W_Sparadoxus | rna-NM_001180847.1_Sparadoxus | cds-NP_010828.1_Sparadoxus | 91.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |