Gene name: FCY1
Reference locus (S288C): YPR062W
Gene biotype: protein_coding
Description: Cytosine deaminase; zinc metalloenzyme that catalyzes the hydrolytic deamination of cytosine to uracil; of biomedical interest because it also catalyzes the deamination of 5-fluorocytosine (5FC) to form anticancer drug 5-fluorouracil (5FU); Belongs to the cytidine and deoxycytidylate deaminase family
Top 10 interactors (score): FUR1 (0.991); URH1 (0.971); TAD3 (0.962); FCY2 (0.939); CDD1 (0.939); PNP1 (0.936); DCD1 (0.911); TAD1 (0.838); CDC21 (0.818); ERV1 (0.79); RIB2 (0.79); TAD2 (0.787); QRI1 (0.767); UNG1 (0.755); FCY22 (0.755); FCY21 (0.722); GIS2 (0.708); YLR256W-A (0.699); YBR209W (0.698); FUI1 (0.632)
Homologues (species, bitscore): ADAT2 (Homo sapiens, 57.8); Adat2 (Mus musculus, 55.1); adat2 (Danio rerio, 52.0); CELE_JC8.4 (Caenorhabditis elegans, 59.3); TADA (Arabidopsis thaliana, 53.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005310.1:648838-649314:+ | gene-YPR062W_AKU4011 | rna-NM_001184159.1_AKU4011 | cds-NP_015387.1_AKU4011 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000091.1:248374-248850:- | gene-YPR062W_BG1 | rna-NM_001184159.1_BG1 | cds-NP_015387.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005518.1:726503-726979:+ | gene-YPR062W_Bruggeman | rna-NM_001184159.1_Bruggeman | cds-NP_015387.1_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005534.1:769952-770428:+ | gene-YPR062W_CAT1 | rna-NM_001184159.1_CAT1 | cds-NP_015387.1_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005374.1:652524-653000:+ | gene-YPR062W_CBS1585 | rna-NM_001184159.1_CBS1585 | cds-NP_015387.1_CBS1585 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005358.1:666894-667370:+ | gene-YPR062W_CBS436 | rna-NM_001184159.1_CBS436 | cds-NP_015387.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005342.1:656272-656748:+ | gene-YPR062W_CBS6412 | rna-NM_001184159.1_CBS6412 | cds-NP_015387.1_CBS6412 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005326.1:649472-649948:+ | gene-YPR062W_CBS6413 | rna-NM_001184159.1_CBS6413 | cds-NP_015387.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001537.1:677129-677605:+ | gene-YPR062W_CENPK1137D | rna-NM_001184159.1_CENPK1137D | cds-NP_015387.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:976030-976506:+ | gene-YPR062W_EthanolRed | rna-NM_001184159.1_EthanolRed | cds-NP_015387.1_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005550.1:654667-655143:+ | gene-YPR062W_FaliES1 | rna-NM_001184159.1_FaliES1 | cds-NP_015387.1_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000446.1:26614-27090:+ | gene-YPR062W_JAY291 | rna-NM_001184159.1_JAY291 | cds-NP_015387.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005422.1:667763-668239:+ | gene-YPR062W_MUCL30387 | rna-NM_001184159.1_MUCL30387 | cds-NP_015387.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005454.1:666468-666944:+ | gene-YPR062W_MUCL30388 | rna-NM_001184159.1_MUCL30388 | cds-NP_015387.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005294.1:645781-646257:+ | gene-YPR062W_MUCL39482 | rna-NM_001184159.1_MUCL39482 | cds-NP_015387.1_MUCL39482 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005438.1:708604-709080:+ | gene-YPR062W_MUCL42920 | rna-NM_001184159.1_MUCL42920 | cds-NP_015387.1_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011825.1:677148-677624:+ | gene-YPR062W_NCIM3186 | rna-NM_001184159.1_NCIM3186 | cds-NP_015387.1_NCIM3186 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005278.1:653711-654187:+ | gene-YPR062W_NCYC1407 | rna-NM_001184159.1_NCYC1407 | cds-NP_015387.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994155.1:659917-660393:+ | gene-YPR062W_PE2H3 | rna-NM_001184159.1_PE2H3 | cds-NP_015387.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999887.1:659565-660041:+ | gene-YPR062W_PE2H4 | rna-NM_001184159.1_PE2H4 | cds-NP_015387.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001148.4:677165-677641:+ | gene-YPR062W_S288C | rna-NM_001184159.1_S288C | cds-NP_015387.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000026.1:23051-23527:- | gene-YPR062W_SA1 | rna-NM_001184159.1_SA1 | cds-NP_015387.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005502.1:654442-654918:+ | gene-YPR062W_ThermosaccDry | rna-NM_001184159.1_ThermosaccDry | cds-NP_015387.1_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005470.1:670591-671067:+ | gene-YPR062W_VR1 | rna-NM_001184159.1_VR1 | cds-NP_015387.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000033.1:653665-654141:+ | gene-YPR062W_ZTW1 | rna-NM_001184159.1_ZTW1 | cds-NP_015387.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047502.1:654419-654895:+ | gene-YPR062W_Sparadoxus | rna-NM_001184159.1_Sparadoxus | cds-NP_015387.1_Sparadoxus | 91.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |