Gene name: FBP1
Reference locus (S288C): YLR377C
Gene biotype: protein_coding
Description: Fructose-1,6-bisphosphatase; key regulatory enzyme in the gluconeogenesis pathway, required for glucose metabolism; undergoes either proteasome-mediated or autophagy-mediated degradation depending on growth conditions; glucose starvation results in redistribution to the periplasm; interacts with Vid30p; Belongs to the FBPase class 1 family
Top 10 interactors (score): PCK1 (0.999); PGI1 (0.995); MLS1 (0.994); ICL1 (0.994); PFK1 (0.994); FBA1 (0.989); SNF4 (0.988); IDP2 (0.987); PFK26 (0.986); TAL1 (0.984); HXK2 (0.983); GLK1 (0.983); PFK27 (0.983); HXK1 (0.982); TKL1 (0.982); SFC1 (0.982); TKL2 (0.976); ACS1 (0.975); YLR446W (0.974); NQM1 (0.972)
Homologues (species, bitscore): FBP1 (Homo sapiens, 303.9); Fbp2 (Mus musculus, 299.7); fbp1a (Danio rerio, 305.8); fbp2 (Xenopus tropicalis, 303.5); Fbp (Drosophila melanogaster, 330.1); fbp-1 (Caenorhabditis elegans, 321.2); FBP (Arabidopsis thaliana, 347.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:823282-824328:- | gene-YLR377C_AKU4011 | rna-NM_001182266.3_AKU4011 | cds-NP_013481.3_AKU4011 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000048.1:55461-56507:- | gene-YLR377C_BG1 | rna-NM_001182266.3_BG1 | cds-NP_013481.3_BG1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:861616-862662:- | gene-YLR377C_Bruggeman | rna-NM_001182266.3_Bruggeman | cds-NP_013481.3_Bruggeman | 99.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:857110-858156:- | gene-YLR377C_CAT1 | rna-NM_001182266.3_CAT1 | cds-NP_013481.3_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:858274-859320:- | gene-YLR377C_CBS1585 | rna-NM_001182266.3_CBS1585 | cds-NP_013481.3_CBS1585 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:842519-843565:- | gene-YLR377C_CBS436 | rna-NM_001182266.3_CBS436 | cds-NP_013481.3_CBS436 | 98.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:895296-896342:- | gene-YLR377C_CBS6412 | rna-NM_001182266.3_CBS6412 | cds-NP_013481.3_CBS6412 | 99.1 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:859167-860213:- | gene-YLR377C_CBS6413 | rna-NM_001182266.3_CBS6413 | cds-NP_013481.3_CBS6413 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:858517-859563:- | gene-YLR377C_CENPK1137D | rna-NM_001182266.3_CENPK1137D | cds-NP_013481.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:815865-816911:- | gene-YLR377C_EthanolRed | rna-NM_001182266.3_EthanolRed | cds-NP_013481.3_EthanolRed | 99.2 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:844670-845716:- | gene-YLR377C_FaliES1 | rna-NM_001182266.3_FaliES1 | cds-NP_013481.3_FaliES1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000161.1:55254-56300:- | gene-YLR377C_JAY291 | rna-NM_001182266.3_JAY291 | cds-NP_013481.3_JAY291 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:859021-860067:- | gene-YLR377C_MUCL30387 | rna-NM_001182266.3_MUCL30387 | cds-NP_013481.3_MUCL30387 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:864650-865696:- | gene-YLR377C_MUCL30388 | rna-NM_001182266.3_MUCL30388 | cds-NP_013481.3_MUCL30388 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:859493-860539:- | gene-YLR377C_MUCL39482 | rna-NM_001182266.3_MUCL39482 | cds-NP_013481.3_MUCL39482 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:854788-855834:- | gene-YLR377C_MUCL42920 | rna-NM_001182266.3_MUCL42920 | cds-NP_013481.3_MUCL42920 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:873720-874766:- | gene-YLR377C_NCIM3186 | rna-NM_001182266.3_NCIM3186 | cds-NP_013481.3_NCIM3186 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:868715-869761:- | gene-YLR377C_NCYC1407 | rna-NM_001182266.3_NCYC1407 | cds-NP_013481.3_NCYC1407 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:855673-856719:- | gene-YLR377C_PE2H3 | rna-NM_001182266.3_PE2H3 | cds-NP_013481.3_PE2H3 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:855417-856463:- | gene-YLR377C_PE2H4 | rna-NM_001182266.3_PE2H4 | cds-NP_013481.3_PE2H4 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:873746-874792:- | gene-YLR377C_S288C | rna-NM_001182266.3_S288C | cds-NP_013481.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000007.1:173898-174944:+ | gene-YLR377C_SA1 | rna-NM_001182266.3_SA1 | cds-NP_013481.3_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:847750-848796:- | gene-YLR377C_ThermosaccDry | rna-NM_001182266.3_ThermosaccDry | cds-NP_013481.3_ThermosaccDry | 99.2 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:860763-861809:- | gene-YLR377C_VR1 | rna-NM_001182266.3_VR1 | cds-NP_013481.3_VR1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000025.1:184933-185979:- | gene-YLR377C_ZTW1 | rna-NM_001182266.3_ZTW1 | cds-NP_013481.3_ZTW1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:833632-834678:- | gene-YLR377C_Sparadoxus | rna-NM_001182266.3_Sparadoxus | cds-NP_013481.3_Sparadoxus | 91.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |