FBA1 (YKL060C)


Gene profile

Gene name: FBA1
Reference locus (S288C): YKL060C
Gene biotype: protein_coding

Description: Fructose 1,6-bisphosphate aldolase; required for glycolysis and gluconeogenesis; catalyzes conversion of fructose 1,6 bisphosphate to glyceraldehyde-3-P and dihydroxyacetone-P; locates to mitochondrial outer surface upon oxidative stress; N-terminally propionylated in vivo; Belongs to the class II fructose-bisphosphate aldolase family

Top 10 interactors (score): TDH2 (0.999); CDC19 (0.999); ENO2 (0.999); GPM1 (0.999); TPI1 (0.999); TDH3 (0.999); ENO1 (0.999); TDH1 (0.999); PGK1 (0.998); PGI1 (0.998); PFK1 (0.996); PDC1 (0.996); FBP1 (0.989); TAL1 (0.988); TKL1 (0.987); ADH1 (0.986); PYK2 (0.985); TEF1 (0.975); PFK2 (0.974); DAK2 (0.973)

Homologues (species, bitscore): AT1G18270 (Arabidopsis thaliana, 67.8)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005305.1:312382-313461:- gene-YKL060C_AKU4011 rna-NM_001179626.1_AKU4011 cds-NP_012863.1_AKU4011 99.6 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000113.1:330491-331570:+ gene-YKL060C_BG1 rna-NM_001179626.1_BG1 cds-NP_012863.1_BG1 99.7 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005513.1:331420-332499:- gene-YKL060C_Bruggeman rna-NM_001179626.1_Bruggeman cds-NP_012863.1_Bruggeman 99.7 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005529.1:327858-328937:- gene-YKL060C_CAT1 rna-NM_001179626.1_CAT1 cds-NP_012863.1_CAT1 99.9 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005369.1:325112-326191:- gene-YKL060C_CBS1585 rna-NM_001179626.1_CBS1585 cds-NP_012863.1_CBS1585 99.6 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005353.1:323267-324346:- gene-YKL060C_CBS436 rna-NM_001179626.1_CBS436 cds-NP_012863.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005337.1:309253-310332:- gene-YKL060C_CBS6412 rna-NM_001179626.1_CBS6412 cds-NP_012863.1_CBS6412 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005321.1:325078-326157:- gene-YKL060C_CBS6413 rna-NM_001179626.1_CBS6413 cds-NP_012863.1_CBS6413 99.6 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001532.1:326069-327148:- gene-YKL060C_CENPK1137D rna-NM_001179626.1_CENPK1137D cds-NP_012863.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005481.1:323085-324164:- gene-YKL060C_EthanolRed rna-NM_001179626.1_EthanolRed cds-NP_012863.1_EthanolRed 99.6 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005545.1:323898-324977:- gene-YKL060C_FaliES1 rna-NM_001179626.1_FaliES1 cds-NP_012863.1_FaliES1 99.6 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000080.1:28829-29908:- gene-YKL060C_JAY291 rna-NM_001179626.1_JAY291 cds-NP_012863.1_JAY291 99.7 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005417.1:332331-333410:- gene-YKL060C_MUCL30387 rna-NM_001179626.1_MUCL30387 cds-NP_012863.1_MUCL30387 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005449.1:327230-328309:- gene-YKL060C_MUCL30388 rna-NM_001179626.1_MUCL30388 cds-NP_012863.1_MUCL30388 99.6 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005289.1:324408-325487:- gene-YKL060C_MUCL39482 rna-NM_001179626.1_MUCL39482 cds-NP_012863.1_MUCL39482 99.6 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005433.1:329317-330396:- gene-YKL060C_MUCL42920 rna-NM_001179626.1_MUCL42920 cds-NP_012863.1_MUCL42920 99.8 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011820.1:326397-327476:- gene-YKL060C_NCIM3186 rna-NM_001179626.1_NCIM3186 cds-NP_012863.1_NCIM3186 99.6 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005273.1:324605-325684:- gene-YKL060C_NCYC1407 rna-NM_001179626.1_NCYC1407 cds-NP_012863.1_NCYC1407 99.6 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994150.1:349170-350249:- gene-YKL060C_PE2H3 rna-NM_001179626.1_PE2H3 cds-NP_012863.1_PE2H3 99.7 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999882.1:333909-334988:- gene-YKL060C_PE2H4 rna-NM_001179626.1_PE2H4 cds-NP_012863.1_PE2H4 99.7 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001143.9:326408-327487:- gene-YKL060C_S288C rna-NM_001179626.1_S288C cds-NP_012863.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000027.1:4409-5488:- gene-YKL060C_SA1 rna-NM_001179626.1_SA1 cds-NP_012863.1_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005497.1:325088-326167:- gene-YKL060C_ThermosaccDry rna-NM_001179626.1_ThermosaccDry cds-NP_012863.1_ThermosaccDry 99.6 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005465.1:324234-325313:- gene-YKL060C_VR1 rna-NM_001179626.1_VR1 cds-NP_012863.1_VR1 99.7 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000022.1:323134-324213:- gene-YKL060C_ZTW1 rna-NM_001179626.1_ZTW1 cds-NP_012863.1_ZTW1 99.8 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047497.1:342342-343421:- gene-YKL060C_Sparadoxus rna-NM_001179626.1_Sparadoxus cds-NP_012863.1_Sparadoxus 97.9 99.9 Verified 1 1 1 False True False False False

Additional files