Gene name: FAR1
Reference locus (S288C): YJL157C
Gene biotype: protein_coding
Description: Cyclin-dependent protein serine/threonine kinase inhibiting protein far1; CDK inhibitor and nuclear anchor; during the cell cycle Far1p sequesters the GEF Cdc24p in the nucleus; phosphorylation by Cdc28p-Cln results in SCFCdc4 complex-mediated ubiquitin-dependent degradation, releasing Cdc24p for export and activation of GTPase Cdc42p; in response to pheromone, phosphorylation of Far1p by MAPK Fus3p results in association with, and inhibition of Cdc28p-Cln, as well as Msn5p mediated nuclear export of Far1p-Cdc24p, targeting Cdc24p to polarity sites
Top 10 interactors (score): FUS3 (0.999); CDC24 (0.999); CDC28 (0.998); CLN2 (0.996); STE4 (0.993); BEM1 (0.981); STE18 (0.974); SST2 (0.973); KSS1 (0.972); GPA1 (0.968); CLN3 (0.966); CDC4 (0.966); CLN1 (0.96); STE5 (0.952); CLB5 (0.942); STE12 (0.937); CDC42 (0.925); SIC1 (0.901); STE7 (0.898); STE2 (0.887)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005304.1:112142-114634:- | gene-YJL157C_AKU4011 | rna-NM_001181590.1_AKU4011 | cds-NP_012378.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000190.1:499069-501561:+ | gene-YJL157C_BG1 | rna-NM_001181590.1_BG1 | cds-NP_012378.1_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005512.1:123974-126466:- | gene-YJL157C_Bruggeman | rna-NM_001181590.1_Bruggeman | cds-NP_012378.1_Bruggeman | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005528.1:127766-130258:- | gene-YJL157C_CAT1 | rna-NM_001181590.1_CAT1 | cds-NP_012378.1_CAT1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005368.1:117777-120269:- | gene-YJL157C_CBS1585 | rna-NM_001181590.1_CBS1585 | cds-NP_012378.1_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005352.1:142538-145030:- | gene-YJL157C_CBS436 | rna-NM_001181590.1_CBS436 | cds-NP_012378.1_CBS436 | 99.0 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005336.1:114186-116678:- | gene-YJL157C_CBS6412 | rna-NM_001181590.1_CBS6412 | cds-NP_012378.1_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005320.1:115249-117741:- | gene-YJL157C_CBS6413 | rna-NM_001181590.1_CBS6413 | cds-NP_012378.1_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001531.1:106240-108732:- | gene-YJL157C_CENPK1137D | rna-NM_001181590.1_CENPK1137D | cds-NP_012378.1_CENPK1137D | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005480.1:116301-118793:- | gene-YJL157C_EthanolRed | rna-NM_001181590.1_EthanolRed | cds-NP_012378.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005544.1:121778-124270:- | gene-YJL157C_FaliES1 | rna-NM_001181590.1_FaliES1 | cds-NP_012378.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000099.1:2958-5450:- | gene-YJL157C_JAY291 | rna-NM_001181590.1_JAY291 | cds-NP_012378.1_JAY291 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005416.1:125799-128291:- | gene-YJL157C_MUCL30387 | rna-NM_001181590.1_MUCL30387 | cds-NP_012378.1_MUCL30387 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005448.1:122277-124769:- | gene-YJL157C_MUCL30388 | rna-NM_001181590.1_MUCL30388 | cds-NP_012378.1_MUCL30388 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005288.1:116519-119011:- | gene-YJL157C_MUCL39482 | rna-NM_001181590.1_MUCL39482 | cds-NP_012378.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005432.1:121799-124291:- | gene-YJL157C_MUCL42920 | rna-NM_001181590.1_MUCL42920 | cds-NP_012378.1_MUCL42920 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011819.1:123815-126307:- | gene-YJL157C_NCIM3186 | rna-NM_001181590.1_NCIM3186 | cds-NP_012378.1_NCIM3186 | 98.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005272.1:115127-117619:- | gene-YJL157C_NCYC1407 | rna-NM_001181590.1_NCYC1407 | cds-NP_012378.1_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994149.1:127938-130430:- | gene-YJL157C_PE2H3 | rna-NM_001181590.1_PE2H3 | cds-NP_012378.1_PE2H3 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999881.1:127577-130069:- | gene-YJL157C_PE2H4 | rna-NM_001181590.1_PE2H4 | cds-NP_012378.1_PE2H4 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001142.9:123836-126328:- | gene-YJL157C_S288C | rna-NM_001181590.1_S288C | cds-NP_012378.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000022.1:27268-29760:+ | gene-YJL157C_SA1 | rna-NM_001181590.1_SA1 | cds-NP_012378.1_SA1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005496.1:114969-117461:- | gene-YJL157C_ThermosaccDry | rna-NM_001181590.1_ThermosaccDry | cds-NP_012378.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005464.1:121654-124550:- | gene-YJL157C_VR1 | rna-NM_001181590.1_VR1 | cds-NP_012378.1_VR1 | 85.5 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000021.1:102424-104915:- | gene-YJL157C_ZTW1 | rna-NM_001181590.1_ZTW1 | cds-NP_012378.1_ZTW1 | 99.1 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047496.1:127563-130055:- | gene-YJL157C_Sparadoxus | rna-NM_001181590.1_Sparadoxus | cds-NP_012378.1_Sparadoxus | 87.4 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |