Gene name: FAP7
Reference locus (S288C): YDL166C
Gene biotype: protein_coding
Description: Adenylate kinase isoenzyme 6 homolog FAP7; Essential NTPase required for small ribosome subunit synthesis; mediates processing of the 20S pre-rRNA at site D in the cytoplasm but associates only transiently with 43S preribosomes via Rps14p; complex with Rps14 is conserved between humans, yeast, and arches; may be the endonuclease for site D; depletion leads to accumulation of pre-40S ribosomes in 80S-like ribosomes; human TAF9 functionally complements the lethality of the null mutation
Top 10 interactors (score): NOB1 (0.991); RPS14A (0.983); ADK1 (0.979); RIO2 (0.959); RPS14B (0.948); NHP2 (0.943); RIO1 (0.943); ADK2 (0.929); RPC19 (0.919); IMP4 (0.913); YNK1 (0.913); ADO1 (0.91); APT1 (0.91); TRM112 (0.905); APT2 (0.903); ADE13 (0.902); CDC19 (0.901); TSR2 (0.901); PYK2 (0.901); YND1 (0.9)
Homologues (species, bitscore): TAF9 (Homo sapiens, 140.2); Ak6 (Mus musculus, 141.0); TAF9 (Danio rerio, 144.8); taf9 (Xenopus tropicalis, 148.3); Ak6 (Drosophila melanogaster, 142.5); E02H1.6 (Caenorhabditis elegans, 135.6); AAK6 (Arabidopsis thaliana, 141.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:147865-148458:- | gene-YDL166C_AKU4011 | rna-NM_001180226.1_AKU4011 | cds-NP_010115.1_AKU4011 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000102.1:401271-401864:+ | gene-YDL166C_BG1 | rna-NM_001180226.1_BG1 | cds-NP_010115.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:163931-164524:- | gene-YDL166C_Bruggeman | rna-NM_001180226.1_Bruggeman | cds-NP_010115.1_Bruggeman | 98.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:162237-162830:- | gene-YDL166C_CAT1 | rna-NM_001180226.1_CAT1 | cds-NP_010115.1_CAT1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:145901-146494:- | gene-YDL166C_CBS1585 | rna-NM_001180226.1_CBS1585 | cds-NP_010115.1_CBS1585 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:162862-163455:- | gene-YDL166C_CBS436 | rna-NM_001180226.1_CBS436 | cds-NP_010115.1_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:145516-146109:- | gene-YDL166C_CBS6412 | rna-NM_001180226.1_CBS6412 | cds-NP_010115.1_CBS6412 | 99.1 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:164327-164920:- | gene-YDL166C_CBS6413 | rna-NM_001180226.1_CBS6413 | cds-NP_010115.1_CBS6413 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:162124-162717:- | gene-YDL166C_CENPK1137D | rna-NM_001180226.1_CENPK1137D | cds-NP_010115.1_CENPK1137D | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:159327-159920:- | gene-YDL166C_EthanolRed | rna-NM_001180226.1_EthanolRed | cds-NP_010115.1_EthanolRed | 98.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:164653-165246:- | gene-YDL166C_FaliES1 | rna-NM_001180226.1_FaliES1 | cds-NP_010115.1_FaliES1 | 98.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000032.1:54316-54909:+ | gene-YDL166C_JAY291 | rna-NM_001180226.1_JAY291 | cds-NP_010115.1_JAY291 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:162227-162820:- | gene-YDL166C_MUCL30387 | rna-NM_001180226.1_MUCL30387 | cds-NP_010115.1_MUCL30387 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:153876-154469:- | gene-YDL166C_MUCL30388 | rna-NM_001180226.1_MUCL30388 | cds-NP_010115.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:147044-147637:- | gene-YDL166C_MUCL39482 | rna-NM_001180226.1_MUCL39482 | cds-NP_010115.1_MUCL39482 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | MBVV01000307.1:21724-22317:+ | gene-YDL166C_MUCL42920 | rna-NM_001180226.1_MUCL42920 | cds-NP_010115.1_MUCL42920 | 98.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:163372-163965:- | gene-YDL166C_NCIM3186 | rna-NM_001180226.1_NCIM3186 | cds-NP_010115.1_NCIM3186 | 98.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:146984-147577:- | gene-YDL166C_NCYC1407 | rna-NM_001180226.1_NCYC1407 | cds-NP_010115.1_NCYC1407 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:154229-154822:- | gene-YDL166C_PE2H3 | rna-NM_001180226.1_PE2H3 | cds-NP_010115.1_PE2H3 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:154233-154826:- | gene-YDL166C_PE2H4 | rna-NM_001180226.1_PE2H4 | cds-NP_010115.1_PE2H4 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:163449-164042:- | gene-YDL166C_S288C | rna-NM_001180226.1_S288C | cds-NP_010115.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000043.1:29002-29595:- | gene-YDL166C_SA1 | rna-NM_001180226.1_SA1 | cds-NP_010115.1_SA1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:164413-165006:- | gene-YDL166C_ThermosaccDry | rna-NM_001180226.1_ThermosaccDry | cds-NP_010115.1_ThermosaccDry | 98.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:165000-165593:- | gene-YDL166C_VR1 | rna-NM_001180226.1_VR1 | cds-NP_010115.1_VR1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000006.1:162544-163137:- | gene-YDL166C_ZTW1 | rna-NM_001180226.1_ZTW1 | cds-NP_010115.1_ZTW1 | 98.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:164655-165248:- | gene-YDL166C_Sparadoxus | rna-NM_001180226.1_Sparadoxus | cds-NP_010115.1_Sparadoxus | 90.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |