FAP1 (YNL023C)


Gene profile

Gene name: FAP1
Reference locus (S288C): YNL023C
Gene biotype: protein_coding

Description: Transcriptional repressor nf-x1; Protein that binds to Fpr1p; confers rapamycin resistance by competing with rapamycin for Fpr1p binding; accumulates in the nucleus upon treatment of cells with rapamycin; has similarity to D. melanogaster shuttle craft and human NFX1

Top 10 interactors (score): FPR1 (0.821); GTF1 (0.765); HRT3 (0.756); YIL161W (0.723); TDA2 (0.714); RTC4 (0.711); RUP1 (0.644); GUK1 (0.626); THS1 (0.619); ASP1 (0.618); YRA1 (0.606); RPN5 (0.581); BDH1 (0.574); SRB7 (0.572); FCY1 (0.567); ASP3-2 (0.564); ASP3-3 (0.563); BET2 (0.561); MEX67 (0.547); MRE11 (0.537)

Homologues (species, bitscore): NFX1 (Homo sapiens, 330.1); Nfx1 (Mus musculus, 325.5); NFX1 (Danio rerio, 321.2); nfx1 (Xenopus tropicalis, 339.3); stc (Drosophila melanogaster, 291.2); nfx-1 (Caenorhabditis elegans, 318.5); NFXL1 (Arabidopsis thaliana, 290.0)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005308.1:570722-573619:- gene-YNL023C_AKU4011 rna-NM_001182862.1_AKU4011 cds-NP_014375.1_AKU4011 99.3 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000155.1:466525-469422:+ gene-YNL023C_BG1 rna-NM_001182862.1_BG1 cds-NP_014375.1_BG1 99.4 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005516.1:588142-591039:- gene-YNL023C_Bruggeman rna-NM_001182862.1_Bruggeman cds-NP_014375.1_Bruggeman 99.8 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005532.1:623591-626488:- gene-YNL023C_CAT1 rna-NM_001182862.1_CAT1 cds-NP_014375.1_CAT1 99.4 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005372.1:576406-579303:- gene-YNL023C_CBS1585 rna-NM_001182862.1_CBS1585 cds-NP_014375.1_CBS1585 99.2 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005356.1:638816-641713:- gene-YNL023C_CBS436 rna-NM_001182862.1_CBS436 cds-NP_014375.1_CBS436 99.4 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005340.1:566239-569136:- gene-YNL023C_CBS6412 rna-NM_001182862.1_CBS6412 cds-NP_014375.1_CBS6412 99.3 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005324.1:567580-570477:- gene-YNL023C_CBS6413 rna-NM_001182862.1_CBS6413 cds-NP_014375.1_CBS6413 99.3 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001535.1:581870-584767:- gene-YNL023C_CENPK1137D rna-NM_001182862.1_CENPK1137D cds-NP_014375.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005484.1:572808-575705:- gene-YNL023C_EthanolRed rna-NM_001182862.1_EthanolRed cds-NP_014375.1_EthanolRed 99.2 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005548.1:563832-566729:- gene-YNL023C_FaliES1 rna-NM_001182862.1_FaliES1 cds-NP_014375.1_FaliES1 99.1 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000387.1:7106-10003:+ gene-YNL023C_JAY291 rna-NM_001182862.1_JAY291 cds-NP_014375.1_JAY291 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005420.1:584024-586921:- gene-YNL023C_MUCL30387 rna-NM_001182862.1_MUCL30387 cds-NP_014375.1_MUCL30387 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005452.1:626818-629715:- gene-YNL023C_MUCL30388 rna-NM_001182862.1_MUCL30388 cds-NP_014375.1_MUCL30388 99.7 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005292.1:568001-570898:- gene-YNL023C_MUCL39482 rna-NM_001182862.1_MUCL39482 cds-NP_014375.1_MUCL39482 99.3 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005436.1:571559-574456:- gene-YNL023C_MUCL42920 rna-NM_001182862.1_MUCL42920 cds-NP_014375.1_MUCL42920 99.4 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011823.1:588232-591129:- gene-YNL023C_NCIM3186 rna-NM_001182862.1_NCIM3186 cds-NP_014375.1_NCIM3186 99.6 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005276.1:570206-573103:- gene-YNL023C_NCYC1407 rna-NM_001182862.1_NCYC1407 cds-NP_014375.1_NCYC1407 99.2 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994153.1:572729-575626:- gene-YNL023C_PE2H3 rna-NM_001182862.1_PE2H3 cds-NP_014375.1_PE2H3 99.4 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999885.1:574047-576944:- gene-YNL023C_PE2H4 rna-NM_001182862.1_PE2H4 cds-NP_014375.1_PE2H4 99.4 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001146.8:588263-591160:- gene-YNL023C_S288C rna-NM_001182862.1_S288C cds-NP_014375.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000109.1:14288-17185:- gene-YNL023C_SA1 rna-NM_001182862.1_SA1 cds-NP_014375.1_SA1 99.4 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005500.1:564419-567316:- gene-YNL023C_ThermosaccDry rna-NM_001182862.1_ThermosaccDry cds-NP_014375.1_ThermosaccDry 99.1 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005468.1:575435-578332:+ gene-YNL023C_VR1 rna-NM_001182862.1_VR1 cds-NP_014375.1_VR1 99.4 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000030.1:466124-469021:+ gene-YNL023C_ZTW1 rna-NM_001182862.1_ZTW1 cds-NP_014375.1_ZTW1 99.3 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047500.1:579517-582414:- gene-YNL023C_Sparadoxus rna-NM_001182862.1_Sparadoxus cds-NP_014375.1_Sparadoxus 89.1 100.0 Verified 1 1 1 False True False False False

Additional files