Gene name: FAL1
Reference locus (S288C): YDR021W
Gene biotype: protein_coding
Description: ATP-dependent RNA helicase FAL1; Nucleolar protein required for maturation of 18S rRNA; member of the eIF4A subfamily of DEAD-box ATP-dependent RNA helicases; 18S rRNA biogenesis defect of the null mutant is functionally complemented by human EIF4A3
Top 10 interactors (score): LCP5 (0.999); SGD1 (0.999); NAM7 (0.998); UPF3 (0.998); CWC22 (0.997); DHR2 (0.997); PRP19 (0.996); SNU114 (0.989); PRP8 (0.979); CEF1 (0.977); BRR2 (0.969); PRP46 (0.969); UTP14 (0.968); PRP45 (0.966); UTP23 (0.964); ROK1 (0.961); UTP25 (0.959); NMD2 (0.959); BFR2 (0.952); CWC27 (0.95)
Homologues (species, bitscore): EIF4A3 (Homo sapiens, 525.4); Eif4a3 (Mus musculus, 525.0); eif4a3 (Danio rerio, 525.4); eif4a3 (Xenopus tropicalis, 526.2); eIF4AIII (Drosophila melanogaster, 525.0); F33D11.10 (Caenorhabditis elegans, 513.8); EIF4A-III (Arabidopsis thaliana, 507.3)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:472730-473929:+ | gene-YDR021W_AKU4011 | rna-NM_001180329.3_AKU4011 | cds-NP_010304.3_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000102.1:75867-77066:- | gene-YDR021W_BG1 | rna-NM_001180329.3_BG1 | cds-NP_010304.3_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:500972-502171:+ | gene-YDR021W_Bruggeman | rna-NM_001180329.3_Bruggeman | cds-NP_010304.3_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:486040-487239:+ | gene-YDR021W_CAT1 | rna-NM_001180329.3_CAT1 | cds-NP_010304.3_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:469321-470520:+ | gene-YDR021W_CBS1585 | rna-NM_001180329.3_CBS1585 | cds-NP_010304.3_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:486304-487503:+ | gene-YDR021W_CBS436 | rna-NM_001180329.3_CBS436 | cds-NP_010304.3_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:466231-467430:+ | gene-YDR021W_CBS6412 | rna-NM_001180329.3_CBS6412 | cds-NP_010304.3_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:488510-489709:+ | gene-YDR021W_CBS6413 | rna-NM_001180329.3_CBS6413 | cds-NP_010304.3_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:485769-486968:+ | gene-YDR021W_CENPK1137D | rna-NM_001180329.3_CENPK1137D | cds-NP_010304.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:480752-481951:+ | gene-YDR021W_EthanolRed | rna-NM_001180329.3_EthanolRed | cds-NP_010304.3_EthanolRed | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:487111-488310:+ | gene-YDR021W_FaliES1 | rna-NM_001180329.3_FaliES1 | cds-NP_010304.3_FaliES1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000042.1:25285-26484:- | gene-YDR021W_JAY291 | rna-NM_001180329.3_JAY291 | cds-NP_010304.3_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:486552-487751:+ | gene-YDR021W_MUCL30387 | rna-NM_001180329.3_MUCL30387 | cds-NP_010304.3_MUCL30387 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:477014-478213:+ | gene-YDR021W_MUCL30388 | rna-NM_001180329.3_MUCL30388 | cds-NP_010304.3_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:470689-471888:+ | gene-YDR021W_MUCL39482 | rna-NM_001180329.3_MUCL39482 | cds-NP_010304.3_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:392344-393543:+ | gene-YDR021W_MUCL42920 | rna-NM_001180329.3_MUCL42920 | cds-NP_010304.3_MUCL42920 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:486727-487926:+ | gene-YDR021W_NCIM3186 | rna-NM_001180329.3_NCIM3186 | cds-NP_010304.3_NCIM3186 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:470122-471321:+ | gene-YDR021W_NCYC1407 | rna-NM_001180329.3_NCYC1407 | cds-NP_010304.3_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:485208-486407:+ | gene-YDR021W_PE2H3 | rna-NM_001180329.3_PE2H3 | cds-NP_010304.3_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:484513-485712:+ | gene-YDR021W_PE2H4 | rna-NM_001180329.3_PE2H4 | cds-NP_010304.3_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:486804-488003:+ | gene-YDR021W_S288C | rna-NM_001180329.3_S288C | cds-NP_010304.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000065.1:13973-15172:+ | gene-YDR021W_SA1 | rna-NM_001180329.3_SA1 | cds-NP_010304.3_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:486590-487789:+ | gene-YDR021W_ThermosaccDry | rna-NM_001180329.3_ThermosaccDry | cds-NP_010304.3_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:491159-492358:+ | gene-YDR021W_VR1 | rna-NM_001180329.3_VR1 | cds-NP_010304.3_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000006.1:484484-485683:+ | gene-YDR021W_ZTW1 | rna-NM_001180329.3_ZTW1 | cds-NP_010304.3_ZTW1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:488278-489477:+ | gene-YDR021W_Sparadoxus | rna-NM_001180329.3_Sparadoxus | cds-NP_010304.3_Sparadoxus | 92.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |