FAB1 (YFR019W)


Gene profile

Gene name: FAB1
Reference locus (S288C): YFR019W
Gene biotype: protein_coding

Description: 1-phosphatidylinositol 3-phosphate 5-kinase FAB1; 1-phosphatidylinositol-3-phosphate 5-kinase; vacuolar membrane kinase that generates phosphatidylinositol (3,5)P2, which is involved in vacuolar sorting and homeostasis

Top 10 interactors (score): VAC14 (0.999); FIG4 (0.999); ATG18 (0.997); VPS34 (0.997); VAC7 (0.997); STT4 (0.993); SAC1 (0.993); VPS15 (0.992); PEP7 (0.992); PIK1 (0.99); LSB6 (0.988); VPS30 (0.984); YMR1 (0.981); TEP1 (0.968); INP52 (0.962); TOR1 (0.961); INP53 (0.96); PLC1 (0.953); PIS1 (0.946); TCP1 (0.942)

Homologues (species, bitscore): PIKFYVE (Homo sapiens, 453.4); Pikfyve (Mus musculus, 454.9); pikfyve (Danio rerio, 462.6); ENSXETP00000059369 (Xenopus tropicalis, 224.9); fab1 (Drosophila melanogaster, 345.5); ppk-3 (Caenorhabditis elegans, 281.2); FAB1A (Arabidopsis thaliana, 419.5)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005300.1:174767-181579:+ gene-YFR019W_AKU4011 rna-NM_001179984.2_AKU4011 cds-NP_116674.2_AKU4011 99.2 99.6 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000071.1:79106-85921:- gene-YFR019W_BG1 rna-NM_001179984.2_BG1 cds-NP_116674.2_BG1 99.2 99.6 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005508.1:176597-183433:+ gene-YFR019W_Bruggeman rna-NM_001179984.2_Bruggeman cds-NP_116674.2_Bruggeman 99.6 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005524.1:180134-186955:+ gene-YFR019W_CAT1 rna-NM_001179984.2_CAT1 cds-NP_116674.2_CAT1 99.1 99.6 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005364.1:176249-183070:+ gene-YFR019W_CBS1585 rna-NM_001179984.2_CBS1585 cds-NP_116674.2_CBS1585 99.3 99.7 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005348.1:149464-156279:+ gene-YFR019W_CBS436 rna-NM_001179984.2_CBS436 cds-NP_116674.2_CBS436 99.1 99.6 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005332.1:175333-182151:+ gene-YFR019W_CBS6412 rna-NM_001179984.2_CBS6412 cds-NP_116674.2_CBS6412 99.3 99.7 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005316.1:177987-184805:+ gene-YFR019W_CBS6413 rna-NM_001179984.2_CBS6413 cds-NP_116674.2_CBS6413 99.3 99.7 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001527.1:180598-187413:+ gene-YFR019W_CENPK1137D rna-NM_001179984.2_CENPK1137D cds-NP_116674.2_CENPK1137D 99.0 99.6 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005476.1:173869-180687:+ gene-YFR019W_EthanolRed rna-NM_001179984.2_EthanolRed cds-NP_116674.2_EthanolRed 99.3 99.7 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005540.1:175517-182335:+ gene-YFR019W_FaliES1 rna-NM_001179984.2_FaliES1 cds-NP_116674.2_FaliES1 99.3 99.7 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000452.1:22258-29073:+ gene-YFR019W_JAY291 rna-NM_001179984.2_JAY291 cds-NP_116674.2_JAY291 99.2 99.6 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005412.1:177840-184658:+ gene-YFR019W_MUCL30387 rna-NM_001179984.2_MUCL30387 cds-NP_116674.2_MUCL30387 99.3 99.7 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005444.1:174079-180903:+ gene-YFR019W_MUCL30388 rna-NM_001179984.2_MUCL30388 cds-NP_116674.2_MUCL30388 99.4 99.8 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005284.1:174177-180989:+ gene-YFR019W_MUCL39482 rna-NM_001179984.2_MUCL39482 cds-NP_116674.2_MUCL39482 99.2 99.6 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005428.1:173476-180312:+ gene-YFR019W_MUCL42920 rna-NM_001179984.2_MUCL42920 cds-NP_116674.2_MUCL42920 99.5 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011815.1:184501-191337:+ gene-YFR019W_NCIM3186 rna-NM_001179984.2_NCIM3186 cds-NP_116674.2_NCIM3186 99.1 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005268.1:175052-181870:+ gene-YFR019W_NCYC1407 rna-NM_001179984.2_NCYC1407 cds-NP_116674.2_NCYC1407 99.3 99.7 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994145.1:194278-201102:+ gene-YFR019W_PE2H3 rna-NM_001179984.2_PE2H3 cds-NP_116674.2_PE2H3 99.3 99.7 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999877.1:193826-200650:+ gene-YFR019W_PE2H4 rna-NM_001179984.2_PE2H4 cds-NP_116674.2_PE2H4 99.3 99.7 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001138.5:184502-191338:+ gene-YFR019W_S288C rna-NM_001179984.2_S288C cds-NP_116674.2_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000011.1:133056-139877:- gene-YFR019W_SA1 rna-NM_001179984.2_SA1 cds-NP_116674.2_SA1 99.0 99.6 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005492.1:174675-181493:+ gene-YFR019W_ThermosaccDry rna-NM_001179984.2_ThermosaccDry cds-NP_116674.2_ThermosaccDry 99.3 99.7 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005460.1:190195-197019:+ gene-YFR019W_VR1 rna-NM_001179984.2_VR1 cds-NP_116674.2_VR1 99.2 99.7 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000013.1:105146-111964:+ gene-YFR019W_ZTW1 rna-NM_001179984.2_ZTW1 cds-NP_116674.2_ZTW1 99.3 99.7 Unannotated 1 1 0 False False False False True
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047492.1:198591-205460:+ gene-YFR019W_Sparadoxus rna-NM_001179984.2_Sparadoxus cds-NP_116674.2_Sparadoxus 89.3 99.7 Verified 1 1 1 False True False False False

Additional files