FAA2 (YER015W)


Gene profile

Gene name: FAA2
Reference locus (S288C): YER015W
Gene biotype: protein_coding

Description: Long-chain-fatty-acid--CoA ligase 2; Medium chain fatty acyl-CoA synthetase; activates imported fatty acids; accepts a wide range of fatty acid chain lengths with a preference for medium chains, C9:0-C13:0; localized to the peroxisome; comparative analysis suggests that a mitochondrially targeted form may result from translation starting at a non-canonical codon upstream of the annotated start codon

Top 10 interactors (score): POX1 (0.999); FOX2 (0.99); PEX11 (0.987); PXA1 (0.983); SPS19 (0.979); PXA2 (0.975); FAS2 (0.965); FAS1 (0.961); CAT2 (0.961); POT1 (0.932); CRC1 (0.923); PEX3 (0.918); FAT1 (0.91); ANT1 (0.9); ECI1 (0.899); PCS60 (0.89); DGA1 (0.869); YJU3 (0.862); PEX5 (0.802); CEM1 (0.8)

Homologues (species, bitscore): ACSL1 (Homo sapiens, 325.5); Acsl1 (Mus musculus, 324.3); acsl5 (Danio rerio, 327.0); acsl1 (Xenopus tropicalis, 328.9); CG3961 (Drosophila melanogaster, 318.5); acs-13 (Caenorhabditis elegans, 325.1); LACS7 (Arabidopsis thaliana, 309.3)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005299.1:178586-180820:+ gene-YER015W_AKU4011 rna-NM_001178906.3_AKU4011 cds-NP_010931.3_AKU4011 99.5 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000011.1:245279-247513:- gene-YER015W_BG1 rna-NM_001178906.3_BG1 cds-NP_010931.3_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005507.1:186445-188679:+ gene-YER015W_Bruggeman rna-NM_001178906.3_Bruggeman cds-NP_010931.3_Bruggeman 99.5 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005523.1:181087-183321:+ gene-YER015W_CAT1 rna-NM_001178906.3_CAT1 cds-NP_010931.3_CAT1 99.8 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005363.1:178509-180743:+ gene-YER015W_CBS1585 rna-NM_001178906.3_CBS1585 cds-NP_010931.3_CBS1585 99.5 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005347.1:180083-182317:+ gene-YER015W_CBS436 rna-NM_001178906.3_CBS436 cds-NP_010931.3_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005331.1:178753-180987:+ gene-YER015W_CBS6412 rna-NM_001178906.3_CBS6412 cds-NP_010931.3_CBS6412 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005315.1:183539-185773:+ gene-YER015W_CBS6413 rna-NM_001178906.3_CBS6413 cds-NP_010931.3_CBS6413 99.5 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001526.1:182403-184637:+ gene-YER015W_CENPK1137D rna-NM_001178906.3_CENPK1137D cds-NP_010931.3_CENPK1137D 99.5 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005475.1:179212-181446:+ gene-YER015W_EthanolRed rna-NM_001178906.3_EthanolRed cds-NP_010931.3_EthanolRed 99.5 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005539.1:179472-181706:+ gene-YER015W_FaliES1 rna-NM_001178906.3_FaliES1 cds-NP_010931.3_FaliES1 99.5 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000024.1:46098-48332:+ gene-YER015W_JAY291 rna-NM_001178906.3_JAY291 cds-NP_010931.3_JAY291 99.2 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005411.1:182638-184872:+ gene-YER015W_MUCL30387 rna-NM_001178906.3_MUCL30387 cds-NP_010931.3_MUCL30387 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005443.1:178913-181147:+ gene-YER015W_MUCL30388 rna-NM_001178906.3_MUCL30388 cds-NP_010931.3_MUCL30388 99.5 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005283.1:177552-179786:+ gene-YER015W_MUCL39482 rna-NM_001178906.3_MUCL39482 cds-NP_010931.3_MUCL39482 99.5 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005427.1:183669-185903:+ gene-YER015W_MUCL42920 rna-NM_001178906.3_MUCL42920 cds-NP_010931.3_MUCL42920 99.5 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011814.1:184540-186774:+ gene-YER015W_NCIM3186 rna-NM_001178906.3_NCIM3186 cds-NP_010931.3_NCIM3186 99.4 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005267.1:182624-184858:+ gene-YER015W_NCYC1407 rna-NM_001178906.3_NCYC1407 cds-NP_010931.3_NCYC1407 99.5 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994144.1:186925-189159:+ gene-YER015W_PE2H3 rna-NM_001178906.3_PE2H3 cds-NP_010931.3_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999876.1:182840-185074:+ gene-YER015W_PE2H4 rna-NM_001178906.3_PE2H4 cds-NP_010931.3_PE2H4 99.2 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001137.3:184541-186775:+ gene-YER015W_S288C rna-NM_001178906.3_S288C cds-NP_010931.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000020.1:56895-59129:- gene-YER015W_SA1 rna-NM_001178906.3_SA1 cds-NP_010931.3_SA1 99.7 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005491.1:180243-182477:+ gene-YER015W_ThermosaccDry rna-NM_001178906.3_ThermosaccDry cds-NP_010931.3_ThermosaccDry 99.5 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005459.1:178984-181218:+ gene-YER015W_VR1 rna-NM_001178906.3_VR1 cds-NP_010931.3_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000009.1:177455-179689:+ gene-YER015W_ZTW1 rna-NM_001178906.3_ZTW1 cds-NP_010931.3_ZTW1 99.6 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047491.1:182062-184296:+ gene-YER015W_Sparadoxus rna-NM_001178906.3_Sparadoxus cds-NP_010931.3_Sparadoxus 89.6 99.9 Verified 1 1 1 False True False False False

Additional files