Gene name: FAA1
Reference locus (S288C): YOR317W
Gene biotype: protein_coding
Description: Long-chain-fatty-acid--CoA ligase 1; Long chain fatty acyl-CoA synthetase; activates fatty acids with a preference for C12:0-C16:0 chain lengths; role in the competitive import of long-chain fatty acids and sphingoid long-chain bases; accounts for most acyl-CoA synthetase activity; localizes to lipid particles and the plasma membrane; role in sphingolipid-to-glycerolipid metabolism; forms ER foci upon replication stress; faa1 faa4 double null complemented by any of human ACSBG1, ACSL1, 3, 4, 5, 6, SLC27A2, or 4
Top 10 interactors (score): POX1 (0.99); FAT1 (0.977); FAA4 (0.966); FAS2 (0.961); FAS1 (0.957); OLE1 (0.895); NMA111 (0.883); FOX2 (0.85); YJU3 (0.827); NMT1 (0.82); MDM1 (0.803); EHT1 (0.798); TGL3 (0.796); DGA1 (0.788); FAA2 (0.787); PXA1 (0.784); TGL4 (0.722); LRO1 (0.716); TGL2 (0.712); ERG6 (0.698)
Homologues (species, bitscore): ACSL4 (Homo sapiens, 303.9); Acsl4 (Mus musculus, 305.8); acsl3b (Danio rerio, 315.5); acsl4 (Xenopus tropicalis, 298.9); Acsl (Drosophila melanogaster, 338.2); acs-17 (Caenorhabditis elegans, 367.5); LACS8 (Arabidopsis thaliana, 341.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:899827-901929:+ | gene-YOR317W_AKU4011 | rna-NM_001183737.3_AKU4011 | cds-NP_014962.3_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000123.1:301836-303938:+ | gene-YOR317W_BG1 | rna-NM_001183737.3_BG1 | cds-NP_014962.3_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:885243-887345:+ | gene-YOR317W_Bruggeman | rna-NM_001183737.3_Bruggeman | cds-NP_014962.3_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:885954-888056:+ | gene-YOR317W_CAT1 | rna-NM_001183737.3_CAT1 | cds-NP_014962.3_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:883647-885749:+ | gene-YOR317W_CBS1585 | rna-NM_001183737.3_CBS1585 | cds-NP_014962.3_CBS1585 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:881476-883578:+ | gene-YOR317W_CBS436 | rna-NM_001183737.3_CBS436 | cds-NP_014962.3_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:879355-881457:+ | gene-YOR317W_CBS6412 | rna-NM_001183737.3_CBS6412 | cds-NP_014962.3_CBS6412 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:888483-890585:+ | gene-YOR317W_CBS6413 | rna-NM_001183737.3_CBS6413 | cds-NP_014962.3_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:909119-911221:+ | gene-YOR317W_CENPK1137D | rna-NM_001183737.3_CENPK1137D | cds-NP_014962.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:875745-877847:+ | gene-YOR317W_EthanolRed | rna-NM_001183737.3_EthanolRed | cds-NP_014962.3_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:881368-883470:+ | gene-YOR317W_FaliES1 | rna-NM_001183737.3_FaliES1 | cds-NP_014962.3_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000078.1:119796-121898:- | gene-YOR317W_JAY291 | rna-NM_001183737.3_JAY291 | cds-NP_014962.3_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:889482-891584:+ | gene-YOR317W_MUCL30387 | rna-NM_001183737.3_MUCL30387 | cds-NP_014962.3_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:897488-899590:+ | gene-YOR317W_MUCL30388 | rna-NM_001183737.3_MUCL30388 | cds-NP_014962.3_MUCL30388 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:890192-892294:+ | gene-YOR317W_MUCL39482 | rna-NM_001183737.3_MUCL39482 | cds-NP_014962.3_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:899662-901764:+ | gene-YOR317W_MUCL42920 | rna-NM_001183737.3_MUCL42920 | cds-NP_014962.3_MUCL42920 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:909232-911334:+ | gene-YOR317W_NCIM3186 | rna-NM_001183737.3_NCIM3186 | cds-NP_014962.3_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:891193-893295:+ | gene-YOR317W_NCYC1407 | rna-NM_001183737.3_NCYC1407 | cds-NP_014962.3_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:889417-891519:+ | gene-YOR317W_PE2H3 | rna-NM_001183737.3_PE2H3 | cds-NP_014962.3_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:905769-907871:+ | gene-YOR317W_PE2H4 | rna-NM_001183737.3_PE2H4 | cds-NP_014962.3_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:909343-911445:+ | gene-YOR317W_S288C | rna-NM_001183737.3_S288C | cds-NP_014962.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000016.1:19668-21770:+ | gene-YOR317W_SA1 | rna-NM_001183737.3_SA1 | cds-NP_014962.3_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:880551-882653:+ | gene-YOR317W_ThermosaccDry | rna-NM_001183737.3_ThermosaccDry | cds-NP_014962.3_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:943839-945941:+ | gene-YOR317W_VR1 | rna-NM_001183737.3_VR1 | cds-NP_014962.3_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:613418-615520:+ | gene-YOR317W_ZTW1 | rna-NM_001183737.3_ZTW1 | cds-NP_014962.3_ZTW1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:887731-889833:+ | gene-YOR317W_Sparadoxus | rna-NM_001183737.3_Sparadoxus | cds-NP_014962.3_Sparadoxus | 91.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |