Gene name: EXO70
Reference locus (S288C): YJL085W
Gene biotype: protein_coding
Description: Subunit of the exocyst complex; the exocyst mediates polarized targeting and tethering of post-Golgi secretory vesicles to active sites of exocytosis prior to SNARE-mediated fusion; PtdIns[4,5]P2-binding protein that localizes to exocytic sites in an actin-independent manner, targeting and anchoring the exocyst with Sec3p; involved in exocyst assembly; direct downstream effector of Rho3p and Cdc42p; relocalizes from bud neck to cytoplasm upon DNA replication stress
Top 10 interactors (score): RHO3 (0.999); SEC6 (0.999); SEC5 (0.999); CDC42 (0.999); EXO84 (0.999); SEC10 (0.999); SEC3 (0.999); SEC8 (0.999); SEC15 (0.999); SEC4 (0.997); SEC1 (0.984); BEM1 (0.982); SEC9 (0.981); RCY1 (0.969); RHO1 (0.963); MYO2 (0.959); COG3 (0.943); BNI1 (0.925); ARF3 (0.925); YPT31 (0.919)
Homologues (species, bitscore): EXOC7 (Homo sapiens, 51.6); Exoc7 (Mus musculus, 53.1); exoc7 (Danio rerio, 59.3); exoc7 (Xenopus tropicalis, 60.5); Exo70 (Drosophila melanogaster, 61.2); EXO70F1 (Arabidopsis thaliana, 74.3)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005304.1:255542-257413:+ | gene-YJL085W_AKU4011 | rna-NM_001181518.1_AKU4011 | cds-NP_012450.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000190.1:357041-358912:- | gene-YJL085W_BG1 | rna-NM_001181518.1_BG1 | cds-NP_012450.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005512.1:266987-268858:+ | gene-YJL085W_Bruggeman | rna-NM_001181518.1_Bruggeman | cds-NP_012450.1_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005528.1:271880-273751:+ | gene-YJL085W_CAT1 | rna-NM_001181518.1_CAT1 | cds-NP_012450.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005368.1:267203-269074:+ | gene-YJL085W_CBS1585 | rna-NM_001181518.1_CBS1585 | cds-NP_012450.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005352.1:285317-287188:+ | gene-YJL085W_CBS436 | rna-NM_001181518.1_CBS436 | cds-NP_012450.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005336.1:256300-258171:+ | gene-YJL085W_CBS6412 | rna-NM_001181518.1_CBS6412 | cds-NP_012450.1_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005320.1:257655-259526:+ | gene-YJL085W_CBS6413 | rna-NM_001181518.1_CBS6413 | cds-NP_012450.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001531.1:255291-257162:+ | gene-YJL085W_CENPK1137D | rna-NM_001181518.1_CENPK1137D | cds-NP_012450.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005480.1:259389-261260:+ | gene-YJL085W_EthanolRed | rna-NM_001181518.1_EthanolRed | cds-NP_012450.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005544.1:270963-272834:+ | gene-YJL085W_FaliES1 | rna-NM_001181518.1_FaliES1 | cds-NP_012450.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000138.1:68587-70458:+ | gene-YJL085W_JAY291 | rna-NM_001181518.1_JAY291 | cds-NP_012450.1_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005416.1:269257-271128:+ | gene-YJL085W_MUCL30387 | rna-NM_001181518.1_MUCL30387 | cds-NP_012450.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005448.1:265334-267205:+ | gene-YJL085W_MUCL30388 | rna-NM_001181518.1_MUCL30388 | cds-NP_012450.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005288.1:259960-261831:+ | gene-YJL085W_MUCL39482 | rna-NM_001181518.1_MUCL39482 | cds-NP_012450.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005432.1:266165-268036:+ | gene-YJL085W_MUCL42920 | rna-NM_001181518.1_MUCL42920 | cds-NP_012450.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011819.1:272806-274677:+ | gene-YJL085W_NCIM3186 | rna-NM_001181518.1_NCIM3186 | cds-NP_012450.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005272.1:258648-260519:+ | gene-YJL085W_NCYC1407 | rna-NM_001181518.1_NCYC1407 | cds-NP_012450.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994149.1:271013-272884:+ | gene-YJL085W_PE2H3 | rna-NM_001181518.1_PE2H3 | cds-NP_012450.1_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999881.1:270657-272528:+ | gene-YJL085W_PE2H4 | rna-NM_001181518.1_PE2H4 | cds-NP_012450.1_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001142.9:272827-274698:+ | gene-YJL085W_S288C | rna-NM_001181518.1_S288C | cds-NP_012450.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000003.1:68517-70388:+ | gene-YJL085W_SA1 | rna-NM_001181518.1_SA1 | cds-NP_012450.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005496.1:264375-266246:+ | gene-YJL085W_ThermosaccDry | rna-NM_001181518.1_ThermosaccDry | cds-NP_012450.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005464.1:265890-267761:+ | gene-YJL085W_VR1 | rna-NM_001181518.1_VR1 | cds-NP_012450.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000021.1:245735-247606:+ | gene-YJL085W_ZTW1 | rna-NM_001181518.1_ZTW1 | cds-NP_012450.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047496.1:269794-271665:+ | gene-YJL085W_Sparadoxus | rna-NM_001181518.1_Sparadoxus | cds-NP_012450.1_Sparadoxus | 90.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |