Gene name: EXO1
Reference locus (S288C): YOR033C
Gene biotype: protein_coding
Description: Exodeoxyribonuclease 1; 5'-3' exonuclease and flap-endonuclease; involved in recombination, double-strand break repair, MMS2 error-free branch of the post replication (PRR) pathway and DNA mismatch repair; role in telomere maintenance; member of the Rad2p nuclease family, with conserved N and I nuclease domains; relative distribution to the nucleus increases upon DNA replication stress; EXO1 has a paralog, DIN7, that arose from the whole genome duplication
Top 10 interactors (score): DNA2 (0.999); MSH2 (0.999); SGS1 (0.999); MLH1 (0.999); YKU70 (0.998); PMS1 (0.996); MRE11 (0.996); RAD51 (0.995); MEC1 (0.994); MSH6 (0.992); SAE2 (0.991); CHK1 (0.989); RAD53 (0.989); CDC13 (0.988); MLH3 (0.987); RAD52 (0.986); MUS81 (0.986); SRS2 (0.986); RAD9 (0.985); MSH3 (0.985)
Homologues (species, bitscore): EXO1 (Homo sapiens, 230.7); Exo1 (Mus musculus, 224.9); exo1 (Danio rerio, 231.5); exo1 (Xenopus tropicalis, 138.7); tos (Drosophila melanogaster, 193.4); exo-1 (Caenorhabditis elegans, 147.1); AT1G29630 (Arabidopsis thaliana, 230.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:376760-378868:- | gene-YOR033C_AKU4011 | rna-NM_001183452.1_AKU4011 | cds-NP_014676.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000152.1:192336-194444:- | gene-YOR033C_BG1 | rna-NM_001183452.1_BG1 | cds-NP_014676.1_BG1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:379500-381608:- | gene-YOR033C_Bruggeman | rna-NM_001183452.1_Bruggeman | cds-NP_014676.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:377655-379763:- | gene-YOR033C_CAT1 | rna-NM_001183452.1_CAT1 | cds-NP_014676.1_CAT1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:371451-373559:- | gene-YOR033C_CBS1585 | rna-NM_001183452.1_CBS1585 | cds-NP_014676.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:375803-377911:- | gene-YOR033C_CBS436 | rna-NM_001183452.1_CBS436 | cds-NP_014676.1_CBS436 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:370805-372913:- | gene-YOR033C_CBS6412 | rna-NM_001183452.1_CBS6412 | cds-NP_014676.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:378180-380288:- | gene-YOR033C_CBS6413 | rna-NM_001183452.1_CBS6413 | cds-NP_014676.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:392419-394527:- | gene-YOR033C_CENPK1137D | rna-NM_001183452.1_CENPK1137D | cds-NP_014676.1_CENPK1137D | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:373458-375566:- | gene-YOR033C_EthanolRed | rna-NM_001183452.1_EthanolRed | cds-NP_014676.1_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:376806-378914:- | gene-YOR033C_FaliES1 | rna-NM_001183452.1_FaliES1 | cds-NP_014676.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000035.1:47452-49560:- | gene-YOR033C_JAY291 | rna-NM_001183452.1_JAY291 | cds-NP_014676.1_JAY291 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:384265-386373:- | gene-YOR033C_MUCL30387 | rna-NM_001183452.1_MUCL30387 | cds-NP_014676.1_MUCL30387 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:387571-389679:- | gene-YOR033C_MUCL30388 | rna-NM_001183452.1_MUCL30388 | cds-NP_014676.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:378934-381042:- | gene-YOR033C_MUCL39482 | rna-NM_001183452.1_MUCL39482 | cds-NP_014676.1_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:393747-395855:- | gene-YOR033C_MUCL42920 | rna-NM_001183452.1_MUCL42920 | cds-NP_014676.1_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:392305-394413:- | gene-YOR033C_NCIM3186 | rna-NM_001183452.1_NCIM3186 | cds-NP_014676.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:385636-387744:- | gene-YOR033C_NCYC1407 | rna-NM_001183452.1_NCYC1407 | cds-NP_014676.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:384472-386580:- | gene-YOR033C_PE2H3 | rna-NM_001183452.1_PE2H3 | cds-NP_014676.1_PE2H3 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:394852-396960:- | gene-YOR033C_PE2H4 | rna-NM_001183452.1_PE2H4 | cds-NP_014676.1_PE2H4 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:392416-394524:- | gene-YOR033C_S288C | rna-NM_001183452.1_S288C | cds-NP_014676.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000001.1:360338-362446:- | gene-YOR033C_SA1 | rna-NM_001183452.1_SA1 | cds-NP_014676.1_SA1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:375346-377454:- | gene-YOR033C_ThermosaccDry | rna-NM_001183452.1_ThermosaccDry | cds-NP_014676.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:376235-378343:- | gene-YOR033C_VR1 | rna-NM_001183452.1_VR1 | cds-NP_014676.1_VR1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:109974-112082:- | gene-YOR033C_ZTW1 | rna-NM_001183452.1_ZTW1 | cds-NP_014676.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:382678-384786:- | gene-YOR033C_Sparadoxus | rna-NM_001183452.1_Sparadoxus | cds-NP_014676.1_Sparadoxus | 89.0 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |