EUG1 (YDR518W)


Gene profile

Gene name: EUG1
Reference locus (S288C): YDR518W
Gene biotype: protein_coding

Description: Protein disulfide-isomerase EUG1; Protein disulfide isomerase of the endoplasmic reticulum lumen; EUG1 has a paralog, PDI1, that arose from the whole genome duplication; function overlaps with that of Pdi1p; may interact with nascent polypeptides in the ER

Top 10 interactors (score): KAR2 (0.999); LHS1 (0.993); ERO1 (0.99); MPD2 (0.987); EPS1 (0.979); CNE1 (0.97); ERV29 (0.946); WBP1 (0.936); FPR2 (0.894); SEC63 (0.876); MPD1 (0.791); SCJ1 (0.76); SEC61 (0.752); ERD2 (0.718); GIS4 (0.711); YBR219C (0.704); YBR220C (0.704); SSH1 (0.697); SFB3 (0.675); SEC62 (0.659)

Homologues (species, bitscore): PDIA3 (Homo sapiens, 178.3); Pdia3 (Mus musculus, 180.3); pdia3 (Danio rerio, 189.9); pdia4 (Xenopus tropicalis, 152.1); Pdi (Drosophila melanogaster, 156.8); pdi-3 (Caenorhabditis elegans, 163.3); PDIL1-1 (Arabidopsis thaliana, 158.7)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005298.1:1418652-1420205:+ gene-YDR518W_AKU4011 rna-NM_001180826.1_AKU4011 cds-NP_010806.1_AKU4011 99.4 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000073.1:60274-61827:+ gene-YDR518W_BG1 rna-NM_001180826.1_BG1 cds-NP_010806.1_BG1 99.8 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:1449939-1451492:+ gene-YDR518W_Bruggeman rna-NM_001180826.1_Bruggeman cds-NP_010806.1_Bruggeman 99.8 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005522.1:1427110-1428663:+ gene-YDR518W_CAT1 rna-NM_001180826.1_CAT1 cds-NP_010806.1_CAT1 99.8 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005362.1:1413378-1414931:+ gene-YDR518W_CBS1585 rna-NM_001180826.1_CBS1585 cds-NP_010806.1_CBS1585 99.4 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005346.1:1432585-1434138:+ gene-YDR518W_CBS436 rna-NM_001180826.1_CBS436 cds-NP_010806.1_CBS436 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005330.1:1408543-1410096:+ gene-YDR518W_CBS6412 rna-NM_001180826.1_CBS6412 cds-NP_010806.1_CBS6412 99.4 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005314.1:1432040-1433593:+ gene-YDR518W_CBS6413 rna-NM_001180826.1_CBS6413 cds-NP_010806.1_CBS6413 99.4 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001525.1:1477298-1478851:+ gene-YDR518W_CENPK1137D rna-NM_001180826.1_CENPK1137D cds-NP_010806.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005474.1:1421911-1423464:+ gene-YDR518W_EthanolRed rna-NM_001180826.1_EthanolRed cds-NP_010806.1_EthanolRed 99.5 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005538.1:1425463-1427016:+ gene-YDR518W_FaliES1 rna-NM_001180826.1_FaliES1 cds-NP_010806.1_FaliES1 99.5 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000026.1:123811-125364:+ gene-YDR518W_JAY291 rna-NM_001180826.1_JAY291 cds-NP_010806.1_JAY291 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005410.1:1433029-1434582:+ gene-YDR518W_MUCL30387 rna-NM_001180826.1_MUCL30387 cds-NP_010806.1_MUCL30387 99.9 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005442.1:1414482-1416035:+ gene-YDR518W_MUCL30388 rna-NM_001180826.1_MUCL30388 cds-NP_010806.1_MUCL30388 99.5 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005282.1:1404876-1406429:+ gene-YDR518W_MUCL39482 rna-NM_001180826.1_MUCL39482 cds-NP_010806.1_MUCL39482 99.4 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005426.1:1347508-1349061:+ gene-YDR518W_MUCL42920 rna-NM_001180826.1_MUCL42920 cds-NP_010806.1_MUCL42920 100.0 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011813.1:1478531-1480084:+ gene-YDR518W_NCIM3186 rna-NM_001180826.1_NCIM3186 cds-NP_010806.1_NCIM3186 99.4 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005266.1:1418168-1419721:+ gene-YDR518W_NCYC1407 rna-NM_001180826.1_NCYC1407 cds-NP_010806.1_NCYC1407 99.4 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994143.1:1429080-1430633:+ gene-YDR518W_PE2H3 rna-NM_001180826.1_PE2H3 cds-NP_010806.1_PE2H3 99.8 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999875.1:1434548-1436101:+ gene-YDR518W_PE2H4 rna-NM_001180826.1_PE2H4 cds-NP_010806.1_PE2H4 99.8 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001136.10:1478608-1480161:+ gene-YDR518W_S288C rna-NM_001180826.1_S288C cds-NP_010806.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000004.1:136951-138504:- gene-YDR518W_SA1 rna-NM_001180826.1_SA1 cds-NP_010806.1_SA1 99.8 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005490.1:1429685-1431238:+ gene-YDR518W_ThermosaccDry rna-NM_001180826.1_ThermosaccDry cds-NP_010806.1_ThermosaccDry 99.5 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005458.1:1445455-1447008:+ gene-YDR518W_VR1 rna-NM_001180826.1_VR1 cds-NP_010806.1_VR1 99.8 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000008.1:472326-473879:+ gene-YDR518W_ZTW1 rna-NM_001180826.1_ZTW1 cds-NP_010806.1_ZTW1 99.7 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047490.1:1438621-1440174:+ gene-YDR518W_Sparadoxus rna-NM_001180826.1_Sparadoxus cds-NP_010806.1_Sparadoxus 90.2 99.8 Verified 1 1 1 False True False False False

Additional files