Gene name: EST1
Reference locus (S288C): YLR233C
Gene biotype: protein_coding
Description: Telomere elongation protein EST1; TLC1 RNA-associated factor involved in telomere length regulation; recruitment subunit of telomerase; has G-quadruplex promoting activity required for telomere elongation; role in activating telomere-bound Est2p-TLC1-RNA; EST1 has a paralog, EBS1, that arose from the whole genome duplication
Top 10 interactors (score): EST3 (0.999); CDC13 (0.999); EST2 (0.999); YKU80 (0.981); NAM7 (0.978); YKU70 (0.978); POP6 (0.964); STN1 (0.958); POP1 (0.951); POP7 (0.946); TEN1 (0.932); RAD52 (0.919); ECM32 (0.919); TEL1 (0.913); RIF2 (0.896); NMD2 (0.88); MPS3 (0.87); CBC2 (0.869); RIF1 (0.861); STO1 (0.854)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:561590-563689:- | gene-YLR233C_AKU4011 | rna-NM_001182120.1_AKU4011 | cds-NP_013334.1_AKU4011 | 98.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000082.1:15648-17747:- | gene-YLR233C_BG1 | rna-NM_001182120.1_BG1 | cds-NP_013334.1_BG1 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:595873-597972:- | gene-YLR233C_Bruggeman | rna-NM_001182120.1_Bruggeman | cds-NP_013334.1_Bruggeman | 98.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:594994-597093:- | gene-YLR233C_CAT1 | rna-NM_001182120.1_CAT1 | cds-NP_013334.1_CAT1 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:597084-599183:- | gene-YLR233C_CBS1585 | rna-NM_001182120.1_CBS1585 | cds-NP_013334.1_CBS1585 | 98.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:581339-583438:- | gene-YLR233C_CBS436 | rna-NM_001182120.1_CBS436 | cds-NP_013334.1_CBS436 | 98.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:560059-562158:- | gene-YLR233C_CBS6412 | rna-NM_001182120.1_CBS6412 | cds-NP_013334.1_CBS6412 | 98.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:597379-599478:- | gene-YLR233C_CBS6413 | rna-NM_001182120.1_CBS6413 | cds-NP_013334.1_CBS6413 | 98.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:592036-594135:- | gene-YLR233C_CENPK1137D | rna-NM_001182120.1_CENPK1137D | cds-NP_013334.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:555171-557270:- | gene-YLR233C_EthanolRed | rna-NM_001182120.1_EthanolRed | cds-NP_013334.1_EthanolRed | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:584096-586195:- | gene-YLR233C_FaliES1 | rna-NM_001182120.1_FaliES1 | cds-NP_013334.1_FaliES1 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000136.1:72697-74796:+ | gene-YLR233C_JAY291 | rna-NM_001182120.1_JAY291 | cds-NP_013334.1_JAY291 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:596731-598830:- | gene-YLR233C_MUCL30387 | rna-NM_001182120.1_MUCL30387 | cds-NP_013334.1_MUCL30387 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:600852-602951:- | gene-YLR233C_MUCL30388 | rna-NM_001182120.1_MUCL30388 | cds-NP_013334.1_MUCL30388 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:598065-600164:- | gene-YLR233C_MUCL39482 | rna-NM_001182120.1_MUCL39482 | cds-NP_013334.1_MUCL39482 | 98.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:592873-594972:- | gene-YLR233C_MUCL42920 | rna-NM_001182120.1_MUCL42920 | cds-NP_013334.1_MUCL42920 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:607399-609498:- | gene-YLR233C_NCIM3186 | rna-NM_001182120.1_NCIM3186 | cds-NP_013334.1_NCIM3186 | 98.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:585054-587153:- | gene-YLR233C_NCYC1407 | rna-NM_001182120.1_NCYC1407 | cds-NP_013334.1_NCYC1407 | 98.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:588813-590912:- | gene-YLR233C_PE2H3 | rna-NM_001182120.1_PE2H3 | cds-NP_013334.1_PE2H3 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:588557-590656:- | gene-YLR233C_PE2H4 | rna-NM_001182120.1_PE2H4 | cds-NP_013334.1_PE2H4 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:607425-609524:- | gene-YLR233C_S288C | rna-NM_001182120.1_S288C | cds-NP_013334.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000013.1:72948-75047:+ | gene-YLR233C_SA1 | rna-NM_001182120.1_SA1 | cds-NP_013334.1_SA1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:586596-588695:- | gene-YLR233C_ThermosaccDry | rna-NM_001182120.1_ThermosaccDry | cds-NP_013334.1_ThermosaccDry | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:597928-600027:- | gene-YLR233C_VR1 | rna-NM_001182120.1_VR1 | cds-NP_013334.1_VR1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000024.1:110883-112982:- | gene-YLR233C_ZTW1 | rna-NM_001182120.1_ZTW1 | cds-NP_013334.1_ZTW1 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:572064-574160:- | gene-YLR233C_Sparadoxus | rna-NM_001182120.1_Sparadoxus | cds-NP_013334.1_Sparadoxus | 85.8 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |