Gene name: ESS1
Reference locus (S288C): YJR017C
Gene biotype: protein_coding
Description: Peptidyl-prolyl cis-trans isomerase ESS1; Peptidylprolyl-cis/trans-isomerase (PPIase); specific for phosphorylated S/T residues N-terminal to proline; regulates phosphorylation of RNAPII large subunit (Rpo21p) C-terminal domain (CTD) at Ser7; associates with phospho-Ser5 form of RNAPII in vivo; present along entire coding length of genes; represses initiation of CUTs; required for efficient termination of mRNA transcription, trimethylation of histone H3; human ortholog PIN1 can complement yeast null and ts mutants; Belongs to the PpiC/parvulin rotamase family
Top 10 interactors (score): RPO21 (0.992); SSU72 (0.988); FCP1 (0.972); PRO3 (0.957); RRD1 (0.937); BYE1 (0.919); FPR2 (0.916); SPT5 (0.915); PCF11 (0.905); PKC1 (0.905); THR4 (0.896); FPR1 (0.893); TYR1 (0.876); CPR1 (0.871); SSN3 (0.871); KIN28 (0.862); CTK1 (0.844); MSS4 (0.835); SUA7 (0.813); SGV1 (0.81)
Homologues (species, bitscore): PIN1 (Homo sapiens, 140.6); Pin1rt1 (Mus musculus, 136.7); pin1 (Danio rerio, 96.7); pin1 (Xenopus tropicalis, 124.0); dod (Drosophila melanogaster, 138.7); pinn-1 (Caenorhabditis elegans, 141.4); PIN1AT (Arabidopsis thaliana, 107.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005304.1:449674-450186:- | gene-YJR017C_AKU4011 | rna-NM_001181675.1_AKU4011 | cds-NP_012551.2_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000190.1:162548-163060:+ | gene-YJR017C_BG1 | rna-NM_001181675.1_BG1 | cds-NP_012551.2_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005512.1:463763-464275:- | gene-YJR017C_Bruggeman | rna-NM_001181675.1_Bruggeman | cds-NP_012551.2_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005528.1:467706-468218:- | gene-YJR017C_CAT1 | rna-NM_001181675.1_CAT1 | cds-NP_012551.2_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005368.1:461263-461775:- | gene-YJR017C_CBS1585 | rna-NM_001181675.1_CBS1585 | cds-NP_012551.2_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005352.1:480233-480745:- | gene-YJR017C_CBS436 | rna-NM_001181675.1_CBS436 | cds-NP_012551.2_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005336.1:449493-450005:- | gene-YJR017C_CBS6412 | rna-NM_001181675.1_CBS6412 | cds-NP_012551.2_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005320.1:451716-452228:- | gene-YJR017C_CBS6413 | rna-NM_001181675.1_CBS6413 | cds-NP_012551.2_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001531.1:449005-449517:- | gene-YJR017C_CENPK1137D | rna-NM_001181675.1_CENPK1137D | cds-NP_012551.2_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005480.1:454657-455169:- | gene-YJR017C_EthanolRed | rna-NM_001181675.1_EthanolRed | cds-NP_012551.2_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005544.1:465873-466385:- | gene-YJR017C_FaliES1 | rna-NM_001181675.1_FaliES1 | cds-NP_012551.2_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000384.1:12110-12622:- | gene-YJR017C_JAY291 | rna-NM_001181675.1_JAY291 | cds-NP_012551.2_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005416.1:464077-464589:- | gene-YJR017C_MUCL30387 | rna-NM_001181675.1_MUCL30387 | cds-NP_012551.2_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005448.1:460620-461132:- | gene-YJR017C_MUCL30388 | rna-NM_001181675.1_MUCL30388 | cds-NP_012551.2_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005288.1:454717-455229:- | gene-YJR017C_MUCL39482 | rna-NM_001181675.1_MUCL39482 | cds-NP_012551.2_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005432.1:460026-460538:- | gene-YJR017C_MUCL42920 | rna-NM_001181675.1_MUCL42920 | cds-NP_012551.2_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011819.1:466500-467012:- | gene-YJR017C_NCIM3186 | rna-NM_001181675.1_NCIM3186 | cds-NP_012551.2_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005272.1:452574-453086:- | gene-YJR017C_NCYC1407 | rna-NM_001181675.1_NCYC1407 | cds-NP_012551.2_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994149.1:470887-471399:- | gene-YJR017C_PE2H3 | rna-NM_001181675.1_PE2H3 | cds-NP_012551.2_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999881.1:464583-465095:- | gene-YJR017C_PE2H4 | rna-NM_001181675.1_PE2H4 | cds-NP_012551.2_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001142.9:466521-467033:- | gene-YJR017C_S288C | rna-NM_001181675.1_S288C | cds-NP_012551.2_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000003.1:262513-263025:- | gene-YJR017C_SA1 | rna-NM_001181675.1_SA1 | cds-NP_012551.2_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005496.1:459523-460035:- | gene-YJR017C_ThermosaccDry | rna-NM_001181675.1_ThermosaccDry | cds-NP_012551.2_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005464.1:461806-462318:- | gene-YJR017C_VR1 | rna-NM_001181675.1_VR1 | cds-NP_012551.2_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000021.1:439451-439963:- | gene-YJR017C_ZTW1 | rna-NM_001181675.1_ZTW1 | cds-NP_012551.2_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047496.1:464260-464772:- | gene-YJR017C_Sparadoxus | rna-NM_001181675.1_Sparadoxus | cds-NP_012551.2_Sparadoxus | 91.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |