Gene name: ERV1
Reference locus (S288C): YGR029W
Gene biotype: protein_coding
Description: Flavin-linked sulfhydryl oxidase of the mitochondrial IMS; N-terminus is an intrinsically disordered domain that in the cytosol helps target Erv1p to mitochondria, and in the intermembrane space oxidizes Mia40p as part of a disulfide relay system that promotes intermembrane space retention of imported proteins; functional ortholog of human GFER (ALR); human GFER carrying N-terminal 21 amino acids of Erv1p functionally complements the lethality of the erv1 null mutation
Top 10 interactors (score): MIA40 (0.999); TIM10 (0.997); TIM9 (0.997); COX17 (0.996); COX19 (0.995); TIM13 (0.993); TIM8 (0.99); CCS1 (0.96); MDM35 (0.959); COA4 (0.955); MIX17 (0.953); COA6 (0.946); MIX14 (0.945); TIM50 (0.932); TIM17 (0.926); CMC2 (0.906); TOM40 (0.899); ALG3 (0.896); HOT13 (0.896); ATM1 (0.895)
Homologues (species, bitscore): GFER (Homo sapiens, 124.0); Gfer (Mus musculus, 123.2); gfer (Danio rerio, 124.8); gfer (Xenopus tropicalis, 122.9); Alr (Drosophila melanogaster, 118.2); F56C11.3 (Caenorhabditis elegans, 137.5); Erv1 (Arabidopsis thaliana, 105.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:539161-539813:+ | gene-YGR029W_AKU4011 | rna-NM_001181158.3_AKU4011 | cds-NP_011543.4_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000060.1:36025-36677:- | gene-YGR029W_BG1 | rna-NM_001181158.3_BG1 | cds-NP_011543.4_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:541425-542077:+ | gene-YGR029W_Bruggeman | rna-NM_001181158.3_Bruggeman | cds-NP_011543.4_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:539490-540142:+ | gene-YGR029W_CAT1 | rna-NM_001181158.3_CAT1 | cds-NP_011543.4_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:540491-541143:+ | gene-YGR029W_CBS1585 | rna-NM_001181158.3_CBS1585 | cds-NP_011543.4_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:535264-535916:+ | gene-YGR029W_CBS436 | rna-NM_001181158.3_CBS436 | cds-NP_011543.4_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:533249-533901:+ | gene-YGR029W_CBS6412 | rna-NM_001181158.3_CBS6412 | cds-NP_011543.4_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:537335-537987:+ | gene-YGR029W_CBS6413 | rna-NM_001181158.3_CBS6413 | cds-NP_011543.4_CBS6413 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:543394-544046:+ | gene-YGR029W_CENPK1137D | rna-NM_001181158.3_CENPK1137D | cds-NP_011543.4_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:527375-528027:+ | gene-YGR029W_EthanolRed | rna-NM_001181158.3_EthanolRed | cds-NP_011543.4_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:530863-531515:+ | gene-YGR029W_FaliES1 | rna-NM_001181158.3_FaliES1 | cds-NP_011543.4_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000020.1:69551-70203:+ | gene-YGR029W_JAY291 | rna-NM_001181158.3_JAY291 | cds-NP_011543.4_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:538059-538711:+ | gene-YGR029W_MUCL30387 | rna-NM_001181158.3_MUCL30387 | cds-NP_011543.4_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:540678-541330:+ | gene-YGR029W_MUCL30388 | rna-NM_001181158.3_MUCL30388 | cds-NP_011543.4_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:536313-536965:+ | gene-YGR029W_MUCL39482 | rna-NM_001181158.3_MUCL39482 | cds-NP_011543.4_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:546093-546745:+ | gene-YGR029W_MUCL42920 | rna-NM_001181158.3_MUCL42920 | cds-NP_011543.4_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:543553-544205:+ | gene-YGR029W_NCIM3186 | rna-NM_001181158.3_NCIM3186 | cds-NP_011543.4_NCIM3186 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:530496-531148:+ | gene-YGR029W_NCYC1407 | rna-NM_001181158.3_NCYC1407 | cds-NP_011543.4_NCYC1407 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:533373-534025:+ | gene-YGR029W_PE2H3 | rna-NM_001181158.3_PE2H3 | cds-NP_011543.4_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:538480-539132:+ | gene-YGR029W_PE2H4 | rna-NM_001181158.3_PE2H4 | cds-NP_011543.4_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:543553-544205:+ | gene-YGR029W_S288C | rna-NM_001181158.3_S288C | cds-NP_011543.4_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000021.1:17709-18361:- | gene-YGR029W_SA1 | rna-NM_001181158.3_SA1 | cds-NP_011543.4_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:550200-550852:+ | gene-YGR029W_ThermosaccDry | rna-NM_001181158.3_ThermosaccDry | cds-NP_011543.4_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:640643-641295:+ | gene-YGR029W_VR1 | rna-NM_001181158.3_VR1 | cds-NP_011543.4_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000015.1:5681-6333:+ | gene-YGR029W_ZTW1 | rna-NM_001181158.3_ZTW1 | cds-NP_011543.4_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:538747-539398:+ | gene-YGR029W_Sparadoxus | rna-NM_001181158.3_Sparadoxus | cds-NP_011543.4_Sparadoxus | 87.5 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |