Gene name: ERS1
Reference locus (S288C): YCR075C
Gene biotype: protein_coding
Description: Protein involved in cystine transport; localizes to the vacuole, plasma membrane and endosome; similarity to human cystinosin, a H(+)-driven transporter involved in L-cystine export from lysosomes and implicated in the disease cystinosis; contains seven transmembrane domains; mutation is functionally complemented by human CTNS
Top 10 interactors (score): MEH1 (0.97); ERD1 (0.96); YPQ1 (0.883); RTC2 (0.84); YPQ2 (0.822); YCR090C (0.749); YDR090C (0.691); ANY1 (0.677); AVT1 (0.67); LSB6 (0.67); VBA1 (0.655); YCT1 (0.653); TDA7 (0.65); YHC3 (0.635); YPT7 (0.625); PRM6 (0.619); YML053C (0.612); AVT6 (0.598); SOL2 (0.584); NCB2 (0.575)
Homologues (species, bitscore): CTNS (Homo sapiens, 92.8); Ctns (Mus musculus, 87.4); ctns (Danio rerio, 89.0); ctns (Xenopus tropicalis, 83.6); CG17119 (Drosophila melanogaster, 84.0); ctns-1 (Caenorhabditis elegans, 75.5); AT5G40670 (Arabidopsis thaliana, 89.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005297.1:242534-243316:- | gene-YCR075C_AKU4011 | rna-NM_001178784.1_AKU4011 | cds-NP_010000.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000067.1:101213-101995:- | gene-YCR075C_BG1 | rna-NM_001178784.1_BG1 | cds-NP_010000.1_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005505.1:238745-239527:- | gene-YCR075C_Bruggeman | rna-NM_001178784.1_Bruggeman | cds-NP_010000.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005521.1:249817-250599:- | gene-YCR075C_CAT1 | rna-NM_001178784.1_CAT1 | cds-NP_010000.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005361.1:237349-238131:- | gene-YCR075C_CBS1585 | rna-NM_001178784.1_CBS1585 | cds-NP_010000.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005345.1:249153-249935:- | gene-YCR075C_CBS436 | rna-NM_001178784.1_CBS436 | cds-NP_010000.1_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005329.1:229051-229833:- | gene-YCR075C_CBS6412 | rna-NM_001178784.1_CBS6412 | cds-NP_010000.1_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005313.1:243399-244181:- | gene-YCR075C_CBS6413 | rna-NM_001178784.1_CBS6413 | cds-NP_010000.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001524.1:247272-248054:- | gene-YCR075C_CENPK1137D | rna-NM_001178784.1_CENPK1137D | cds-NP_010000.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005473.1:238417-239131:- | gene-YCR075C_EthanolRed | rna-NM_001178784.1_EthanolRed | cds-NP_010000.1_EthanolRed | 87.9 | 90.4 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005537.1:243712-244494:- | gene-YCR075C_FaliES1 | rna-NM_001178784.1_FaliES1 | cds-NP_010000.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000323.1:44273-45055:+ | gene-YCR075C_JAY291 | rna-NM_001178784.1_JAY291 | cds-NP_010000.1_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005409.1:235897-236679:- | gene-YCR075C_MUCL30387 | rna-NM_001178784.1_MUCL30387 | cds-NP_010000.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005441.1:235740-236522:- | gene-YCR075C_MUCL30388 | rna-NM_001178784.1_MUCL30388 | cds-NP_010000.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005281.1:243913-244695:- | gene-YCR075C_MUCL39482 | rna-NM_001178784.1_MUCL39482 | cds-NP_010000.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005425.1:240319-241101:- | gene-YCR075C_MUCL42920 | rna-NM_001178784.1_MUCL42920 | cds-NP_010000.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011812.1:247665-248447:- | gene-YCR075C_NCIM3186 | rna-NM_001178784.1_NCIM3186 | cds-NP_010000.1_NCIM3186 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005265.1:244743-245525:- | gene-YCR075C_NCYC1407 | rna-NM_001178784.1_NCYC1407 | cds-NP_010000.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994142.1:259332-260114:- | gene-YCR075C_PE2H3 | rna-NM_001178784.1_PE2H3 | cds-NP_010000.1_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999874.1:247886-248668:- | gene-YCR075C_PE2H4 | rna-NM_001178784.1_PE2H4 | cds-NP_010000.1_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001135.5:248033-248815:- | gene-YCR075C_S288C | rna-NM_001178784.1_S288C | cds-NP_010000.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000044.1:47904-48686:- | gene-YCR075C_SA1 | rna-NM_001178784.1_SA1 | cds-NP_010000.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005489.1:243639-244421:- | gene-YCR075C_ThermosaccDry | rna-NM_001178784.1_ThermosaccDry | cds-NP_010000.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005457.1:254871-255653:- | gene-YCR075C_VR1 | rna-NM_001178784.1_VR1 | cds-NP_010000.1_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000004.1:241494-242276:- | gene-YCR075C_ZTW1 | rna-NM_001178784.1_ZTW1 | cds-NP_010000.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047489.1:275666-276447:- | gene-YCR075C_Sparadoxus | rna-NM_001178784.1_Sparadoxus | cds-NP_010000.1_Sparadoxus | 89.9 | 99.8 | Verified | 1 | 1 | 0 | False | False | False | True | False |