ERP2 (YAL007C)


Gene profile

Gene name: ERP2
Reference locus (S288C): YAL007C
Gene biotype: protein_coding

Description: Protein ERP2; Member of the p24 family involved in ER to Golgi transport; similar to Emp24p and Erv25p; role in misfolded protein quality control; forms a heterotrimeric complex with Erp1p, Emp24p, and Erv25p; localized to COPII-coated vesicles; ERP2 has a paralog, ERP4, that arose from the whole genome duplication

Top 10 interactors (score): ERP4 (0.999); ERP1 (0.998); ERV25 (0.998); ERP6 (0.981); ERP5 (0.945); EMP24 (0.943); ERV29 (0.895); ERD2 (0.799); KAR2 (0.791); ERV14 (0.786); ERV15 (0.786); RET3 (0.779); EMP47 (0.749); ERV46 (0.716); RRT6 (0.712); BET1 (0.706); COP1 (0.7); RET2 (0.696); ALG12 (0.692); SEC22 (0.68)

Homologues (species, bitscore): TMED5 (Homo sapiens, 86.3); Tmed7 (Mus musculus, 86.3); tmed7 (Danio rerio, 89.0); tmed7 (Xenopus tropicalis, 87.0); CG31787 (Drosophila melanogaster, 62.8); sel-9 (Caenorhabditis elegans, 63.5); AT3G22845 (Arabidopsis thaliana, 67.8)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005295.1:122810-123457:- gene-YAL007C_AKU4011 rna-NM_001178152.1_AKU4011 cds-NP_009395.1_AKU4011 99.6 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000070.1:109760-110407:- gene-YAL007C_BG1 rna-NM_001178152.1_BG1 cds-NP_009395.1_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005503.1:137683-138330:- gene-YAL007C_Bruggeman rna-NM_001178152.1_Bruggeman cds-NP_009395.1_Bruggeman 100.0 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005519.1:124020-124667:- gene-YAL007C_CAT1 rna-NM_001178152.1_CAT1 cds-NP_009395.1_CAT1 99.8 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005359.1:135822-136469:- gene-YAL007C_CBS1585 rna-NM_001178152.1_CBS1585 cds-NP_009395.1_CBS1585 99.8 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005343.1:136100-136747:- gene-YAL007C_CBS436 rna-NM_001178152.1_CBS436 cds-NP_009395.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005338.1:748916-749563:- gene-YAL007C_CBS6412 rna-NM_001178152.1_CBS6412 cds-NP_009395.1_CBS6412 99.6 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005311.1:134092-134739:- gene-YAL007C_CBS6413 rna-NM_001178152.1_CBS6413 cds-NP_009395.1_CBS6413 99.8 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001522.1:137858-138505:- gene-YAL007C_CENPK1137D rna-NM_001178152.1_CENPK1137D cds-NP_009395.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005471.1:124229-124876:- gene-YAL007C_EthanolRed rna-NM_001178152.1_EthanolRed cds-NP_009395.1_EthanolRed 99.8 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005535.1:138856-139503:- gene-YAL007C_FaliES1 rna-NM_001178152.1_FaliES1 cds-NP_009395.1_FaliES1 99.8 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000084.1:110127-110774:- gene-YAL007C_JAY291 rna-NM_001178152.1_JAY291 cds-NP_009395.1_JAY291 99.8 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005407.1:138836-139483:- gene-YAL007C_MUCL30387 rna-NM_001178152.1_MUCL30387 cds-NP_009395.1_MUCL30387 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005439.1:136083-136730:- gene-YAL007C_MUCL30388 rna-NM_001178152.1_MUCL30388 cds-NP_009395.1_MUCL30388 100.0 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005279.1:134604-135251:- gene-YAL007C_MUCL39482 rna-NM_001178152.1_MUCL39482 cds-NP_009395.1_MUCL39482 99.6 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005423.1:136985-137632:- gene-YAL007C_MUCL42920 rna-NM_001178152.1_MUCL42920 cds-NP_009395.1_MUCL42920 100.0 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011810.1:137575-138222:- gene-YAL007C_NCIM3186 rna-NM_001178152.1_NCIM3186 cds-NP_009395.1_NCIM3186 99.6 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005263.1:122487-123134:- gene-YAL007C_NCYC1407 rna-NM_001178152.1_NCYC1407 cds-NP_009395.1_NCYC1407 100.0 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994140.1:124415-125062:- gene-YAL007C_PE2H3 rna-NM_001178152.1_PE2H3 cds-NP_009395.1_PE2H3 99.8 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999872.1:124134-124781:- gene-YAL007C_PE2H4 rna-NM_001178152.1_PE2H4 cds-NP_009395.1_PE2H4 99.8 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001133.9:137698-138345:- gene-YAL007C_S288C rna-NM_001178152.1_S288C cds-NP_009395.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000077.1:54619-55266:- gene-YAL007C_SA1 rna-NM_001178152.1_SA1 cds-NP_009395.1_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005487.1:138348-138995:- gene-YAL007C_ThermosaccDry rna-NM_001178152.1_ThermosaccDry cds-NP_009395.1_ThermosaccDry 99.8 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005455.1:139658-140305:- gene-YAL007C_VR1 rna-NM_001178152.1_VR1 cds-NP_009395.1_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000002.1:110176-110823:- gene-YAL007C_ZTW1 rna-NM_001178152.1_ZTW1 cds-NP_009395.1_ZTW1 99.8 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047487.1:127705-128352:- gene-YAL007C_Sparadoxus rna-NM_001178152.1_Sparadoxus cds-NP_009395.1_Sparadoxus 92.5 100.0 Verified 1 1 1 False True False False False

Additional files