ERJ5 (YFR041C)


Gene profile

Gene name: ERJ5
Reference locus (S288C): YFR041C
Gene biotype: protein_coding

Description: ER-localized J domain-containing protein 5; Type I membrane protein with a J domain; required to preserve the folding capacity of the endoplasmic reticulum; loss of the non-essential ERJ5 gene leads to a constitutively induced unfolded protein response

Top 10 interactors (score): KAR2 (0.987); SEC63 (0.956); CWC23 (0.898); SCJ1 (0.883); JEM1 (0.872); SWA2 (0.853); XDJ1 (0.843); APJ1 (0.843); JJJ2 (0.827); MDJ1 (0.827); HLJ1 (0.827); JJJ3 (0.827); SIS1 (0.825); JJJ1 (0.811); MDJ2 (0.802); PAM18 (0.801); DJP1 (0.8); CAJ1 (0.8); JAC1 (0.787); JID1 (0.786)

Homologues (species, bitscore): DNAJC1 (Homo sapiens, 66.6); Dnajc1 (Mus musculus, 66.2); dnajc1 (Danio rerio, 57.8); dnajc1 (Xenopus tropicalis, 62.8); CG7556 (Drosophila melanogaster, 72.8); F54F2.9 (Caenorhabditis elegans, 58.2)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005300.1:227517-228404:- gene-YFR041C_AKU4011 rna-NM_001180006.3_AKU4011 cds-NP_116699.3_AKU4011 100.0 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000071.1:32607-33494:+ gene-YFR041C_BG1 rna-NM_001180006.3_BG1 cds-NP_116699.3_BG1 99.5 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005508.1:231173-232060:- gene-YFR041C_Bruggeman rna-NM_001180006.3_Bruggeman cds-NP_116699.3_Bruggeman 99.5 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005524.1:233141-234028:- gene-YFR041C_CAT1 rna-NM_001180006.3_CAT1 cds-NP_116699.3_CAT1 99.5 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005364.1:229017-229904:- gene-YFR041C_CBS1585 rna-NM_001180006.3_CBS1585 cds-NP_116699.3_CBS1585 100.0 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005348.1:201976-202863:- gene-YFR041C_CBS436 rna-NM_001180006.3_CBS436 cds-NP_116699.3_CBS436 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005332.1:228092-228979:- gene-YFR041C_CBS6412 rna-NM_001180006.3_CBS6412 cds-NP_116699.3_CBS6412 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005316.1:230765-231652:- gene-YFR041C_CBS6413 rna-NM_001180006.3_CBS6413 cds-NP_116699.3_CBS6413 100.0 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001527.1:233457-234344:- gene-YFR041C_CENPK1137D rna-NM_001180006.3_CENPK1137D cds-NP_116699.3_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005476.1:226635-227522:- gene-YFR041C_EthanolRed rna-NM_001180006.3_EthanolRed cds-NP_116699.3_EthanolRed 99.5 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005540.1:228285-229172:- gene-YFR041C_FaliES1 rna-NM_001180006.3_FaliES1 cds-NP_116699.3_FaliES1 99.5 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000453.1:31414-32301:- gene-YFR041C_JAY291 rna-NM_001180006.3_JAY291 cds-NP_116699.3_JAY291 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005412.1:231622-232509:- gene-YFR041C_MUCL30387 rna-NM_001180006.3_MUCL30387 cds-NP_116699.3_MUCL30387 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005444.1:227102-227989:- gene-YFR041C_MUCL30388 rna-NM_001180006.3_MUCL30388 cds-NP_116699.3_MUCL30388 99.8 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005284.1:226939-227826:- gene-YFR041C_MUCL39482 rna-NM_001180006.3_MUCL39482 cds-NP_116699.3_MUCL39482 100.0 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005428.1:226539-227426:- gene-YFR041C_MUCL42920 rna-NM_001180006.3_MUCL42920 cds-NP_116699.3_MUCL42920 99.5 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011815.1:237367-238254:- gene-YFR041C_NCIM3186 rna-NM_001180006.3_NCIM3186 cds-NP_116699.3_NCIM3186 99.3 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005268.1:227789-228676:- gene-YFR041C_NCYC1407 rna-NM_001180006.3_NCYC1407 cds-NP_116699.3_NCYC1407 100.0 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994145.1:269824-270711:- gene-YFR041C_PE2H3 rna-NM_001180006.3_PE2H3 cds-NP_116699.3_PE2H3 99.5 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999877.1:269372-270259:- gene-YFR041C_PE2H4 rna-NM_001180006.3_PE2H4 cds-NP_116699.3_PE2H4 99.5 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001138.5:237368-238255:- gene-YFR041C_S288C rna-NM_001180006.3_S288C cds-NP_116699.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000086.1:32850-33737:+ gene-YFR041C_SA1 rna-NM_001180006.3_SA1 cds-NP_116699.3_SA1 99.5 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005492.1:227454-228341:- gene-YFR041C_ThermosaccDry rna-NM_001180006.3_ThermosaccDry cds-NP_116699.3_ThermosaccDry 99.5 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005460.1:243206-244093:- gene-YFR041C_VR1 rna-NM_001180006.3_VR1 cds-NP_116699.3_VR1 99.5 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000013.1:157903-158790:- gene-YFR041C_ZTW1 rna-NM_001180006.3_ZTW1 cds-NP_116699.3_ZTW1 99.5 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047492.1:250975-251862:- gene-YFR041C_Sparadoxus rna-NM_001180006.3_Sparadoxus cds-NP_116699.3_Sparadoxus 89.0 100.0 Verified 1 1 1 False True False False False

Additional files