ERG8 (YMR220W)


Gene profile

Gene name: ERG8
Reference locus (S288C): YMR220W
Gene biotype: protein_coding

Description: Phosphomevalonate kinase; an essential cytosolic enzyme that acts in the biosynthesis of isoprenoids and sterols, including ergosterol, from mevalonate

Top 10 interactors (score): MVD1 (0.999); ERG12 (0.999); ERG13 (0.994); ERG20 (0.98); ERG10 (0.98); IDI1 (0.98); ERG9 (0.958); ERG7 (0.949); HMG1 (0.92); ERG27 (0.917); PRP19 (0.9); ERG24 (0.894); HMG2 (0.892); ERG26 (0.891); ERG1 (0.885); ERG6 (0.884); ERG11 (0.883); ERG5 (0.86); ERG25 (0.857); ERG2 (0.838)

Homologues (species, bitscore): AT1G31910 (Arabidopsis thaliana, 165.6)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005307.1:752222-753577:+ gene-YMR220W_AKU4011 rna-NM_001182727.1_AKU4011 cds-NP_013947.1_AKU4011 99.1 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000069.1:201031-202386:- gene-YMR220W_BG1 rna-NM_001182727.1_BG1 cds-NP_013947.1_BG1 99.0 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005515.1:696451-697806:+ gene-YMR220W_Bruggeman rna-NM_001182727.1_Bruggeman cds-NP_013947.1_Bruggeman 99.6 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005531.1:700325-701680:+ gene-YMR220W_CAT1 rna-NM_001182727.1_CAT1 cds-NP_013947.1_CAT1 99.7 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005371.1:684483-685838:+ gene-YMR220W_CBS1585 rna-NM_001182727.1_CBS1585 cds-NP_013947.1_CBS1585 99.1 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005355.1:688752-690107:+ gene-YMR220W_CBS436 rna-NM_001182727.1_CBS436 cds-NP_013947.1_CBS436 99.7 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005339.1:796044-797399:+ gene-YMR220W_CBS6412 rna-NM_001182727.1_CBS6412 cds-NP_013947.1_CBS6412 99.1 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005323.1:683635-684990:+ gene-YMR220W_CBS6413 rna-NM_001182727.1_CBS6413 cds-NP_013947.1_CBS6413 99.1 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001534.1:707021-708376:+ gene-YMR220W_CENPK1137D rna-NM_001182727.1_CENPK1137D cds-NP_013947.1_CENPK1137D 99.0 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005486.1:744689-746044:+ gene-YMR220W_EthanolRed rna-NM_001182727.1_EthanolRed cds-NP_013947.1_EthanolRed 99.0 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005547.1:690341-691696:+ gene-YMR220W_FaliES1 rna-NM_001182727.1_FaliES1 cds-NP_013947.1_FaliES1 99.1 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000141.1:94340-95695:- gene-YMR220W_JAY291 rna-NM_001182727.1_JAY291 cds-NP_013947.1_JAY291 99.0 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005419.1:690234-691589:+ gene-YMR220W_MUCL30387 rna-NM_001182727.1_MUCL30387 cds-NP_013947.1_MUCL30387 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005451.1:697462-698817:+ gene-YMR220W_MUCL30388 rna-NM_001182727.1_MUCL30388 cds-NP_013947.1_MUCL30388 99.5 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005291.1:685553-686908:+ gene-YMR220W_MUCL39482 rna-NM_001182727.1_MUCL39482 cds-NP_013947.1_MUCL39482 99.1 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005435.1:692897-694252:+ gene-YMR220W_MUCL42920 rna-NM_001182727.1_MUCL42920 cds-NP_013947.1_MUCL42920 99.4 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011822.1:712270-713625:+ gene-YMR220W_NCIM3186 rna-NM_001182727.1_NCIM3186 cds-NP_013947.1_NCIM3186 99.0 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005275.1:685209-686564:+ gene-YMR220W_NCYC1407 rna-NM_001182727.1_NCYC1407 cds-NP_013947.1_NCYC1407 99.1 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994152.1:695072-696427:+ gene-YMR220W_PE2H3 rna-NM_001182727.1_PE2H3 cds-NP_013947.1_PE2H3 99.8 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999884.1:696087-697442:+ gene-YMR220W_PE2H4 rna-NM_001182727.1_PE2H4 cds-NP_013947.1_PE2H4 99.8 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001145.3:712316-713671:+ gene-YMR220W_S288C rna-NM_001182727.1_S288C cds-NP_013947.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000002.1:94454-95809:- gene-YMR220W_SA1 rna-NM_001182727.1_SA1 cds-NP_013947.1_SA1 99.0 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005499.1:686512-687867:+ gene-YMR220W_ThermosaccDry rna-NM_001182727.1_ThermosaccDry cds-NP_013947.1_ThermosaccDry 99.1 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005467.1:699595-700950:+ gene-YMR220W_VR1 rna-NM_001182727.1_VR1 cds-NP_013947.1_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000028.1:102218-103573:+ gene-YMR220W_ZTW1 rna-NM_001182727.1_ZTW1 cds-NP_013947.1_ZTW1 99.0 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047499.1:704461-705816:+ gene-YMR220W_Sparadoxus rna-NM_001182727.1_Sparadoxus cds-NP_013947.1_Sparadoxus 88.0 99.7 Verified 1 1 1 False True False False False

Additional files