Gene name: ERG7
Reference locus (S288C): YHR072W
Gene biotype: protein_coding
Description: Lanosterol synthase; an essential enzyme that catalyzes the cyclization of squalene 2,3-epoxide, a step in ergosterol biosynthesis; human LSS functionally complements the lethality of the erg7 null mutation; Belongs to the terpene cyclase/mutase family
Top 10 interactors (score): ERG11 (0.999); ERG28 (0.999); ERG26 (0.999); ERG25 (0.999); ERG1 (0.999); ERG3 (0.999); ERG27 (0.999); ERG9 (0.998); ERG6 (0.998); ERG5 (0.997); MVD1 (0.994); ERG24 (0.987); IDI1 (0.986); ERG4 (0.985); ERG13 (0.97); ERG20 (0.967); ERG12 (0.966); ERG2 (0.96); ERG8 (0.949); ERG10 (0.917)
Homologues (species, bitscore): LSS (Homo sapiens, 544.7); Lss (Mus musculus, 545.4); lss (Danio rerio, 548.9); lss (Xenopus tropicalis, 500.4); CAS1 (Arabidopsis thaliana, 468.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005302.1:225512-227707:+ | gene-YHR072W_AKU4011 | rna-NM_001179202.2_AKU4011 | cds-NP_011939.2_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000053.1:145865-148060:+ | gene-YHR072W_BG1 | rna-NM_001179202.2_BG1 | cds-NP_011939.2_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005510.1:233345-235540:+ | gene-YHR072W_Bruggeman | rna-NM_001179202.2_Bruggeman | cds-NP_011939.2_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005526.1:227987-230182:+ | gene-YHR072W_CAT1 | rna-NM_001179202.2_CAT1 | cds-NP_011939.2_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005366.1:224552-226747:+ | gene-YHR072W_CBS1585 | rna-NM_001179202.2_CBS1585 | cds-NP_011939.2_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005350.1:222418-224613:+ | gene-YHR072W_CBS436 | rna-NM_001179202.2_CBS436 | cds-NP_011939.2_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005334.1:227898-230093:+ | gene-YHR072W_CBS6412 | rna-NM_001179202.2_CBS6412 | cds-NP_011939.2_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005318.1:225593-227788:+ | gene-YHR072W_CBS6413 | rna-NM_001179202.2_CBS6413 | cds-NP_011939.2_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001529.1:232268-234463:+ | gene-YHR072W_CENPK1137D | rna-NM_001179202.2_CENPK1137D | cds-NP_011939.2_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005478.1:285110-287305:+ | gene-YHR072W_EthanolRed | rna-NM_001179202.2_EthanolRed | cds-NP_011939.2_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005542.1:225914-228109:+ | gene-YHR072W_FaliES1 | rna-NM_001179202.2_FaliES1 | cds-NP_011939.2_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000394.1:8659-10854:+ | gene-YHR072W_JAY291 | rna-NM_001179202.2_JAY291 | cds-NP_011939.2_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005414.1:232855-235050:+ | gene-YHR072W_MUCL30387 | rna-NM_001179202.2_MUCL30387 | cds-NP_011939.2_MUCL30387 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005446.1:232723-234918:+ | gene-YHR072W_MUCL30388 | rna-NM_001179202.2_MUCL30388 | cds-NP_011939.2_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005286.1:224877-227072:+ | gene-YHR072W_MUCL39482 | rna-NM_001179202.2_MUCL39482 | cds-NP_011939.2_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005430.1:231622-233817:+ | gene-YHR072W_MUCL42920 | rna-NM_001179202.2_MUCL42920 | cds-NP_011939.2_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011817.1:238980-241175:+ | gene-YHR072W_NCIM3186 | rna-NM_001179202.2_NCIM3186 | cds-NP_011939.2_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005270.1:227341-229536:+ | gene-YHR072W_NCYC1407 | rna-NM_001179202.2_NCYC1407 | cds-NP_011939.2_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994147.1:227023-229218:+ | gene-YHR072W_PE2H3 | rna-NM_001179202.2_PE2H3 | cds-NP_011939.2_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999879.1:234470-236665:+ | gene-YHR072W_PE2H4 | rna-NM_001179202.2_PE2H4 | cds-NP_011939.2_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001140.6:239098-241293:+ | gene-YHR072W_S288C | rna-NM_001179202.2_S288C | cds-NP_011939.2_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000014.1:117691-119886:- | gene-YHR072W_SA1 | rna-NM_001179202.2_SA1 | cds-NP_011939.2_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005494.1:227005-229200:+ | gene-YHR072W_ThermosaccDry | rna-NM_001179202.2_ThermosaccDry | cds-NP_011939.2_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005462.1:234649-236844:+ | gene-YHR072W_VR1 | rna-NM_001179202.2_VR1 | cds-NP_011939.2_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000017.1:218552-220748:+ | gene-YHR072W_ZTW1 | rna-NM_001179202.2_ZTW1 | cds-NP_011939.2_ZTW1 | 99.8 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047494.1:224378-226573:+ | gene-YHR072W_Sparadoxus | rna-NM_001179202.2_Sparadoxus | cds-NP_011939.2_Sparadoxus | 91.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |