ERG6 (YML008C)


Gene profile

Gene name: ERG6
Reference locus (S288C): YML008C
Gene biotype: protein_coding

Description: Delta(24)-sterol C-methyltransferase; converts zymosterol to fecosterol in the ergosterol biosynthetic pathway by methylating position C-24; localized to lipid particles, the plasma membrane-associated endoplasmic reticulum, and the mitochondrial outer membrane

Top 10 interactors (score): ERG28 (0.999); ERG26 (0.999); ERG2 (0.999); ERG4 (0.999); ERG27 (0.999); ERG11 (0.999); ERG24 (0.999); ERG5 (0.999); ERG3 (0.999); ERG7 (0.998); ERG25 (0.998); ERG9 (0.996); ERG13 (0.989); ERG1 (0.978); ERG10 (0.953); ERG20 (0.936); MVD1 (0.92); ERG8 (0.884); ERG12 (0.88); PDR5 (0.865)

Homologues (species, bitscore): pmt (Danio rerio, 55.1); LOC100124841 (Xenopus tropicalis, 62.0); H14E04.1 (Caenorhabditis elegans, 116.7); SMT1 (Arabidopsis thaliana, 336.3)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005307.1:301393-302544:- gene-YML008C_AKU4011 rna-NM_001182363.1_AKU4011 cds-NP_013706.1_AKU4011 99.9 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000201.1:240267-241418:+ gene-YML008C_BG1 rna-NM_001182363.1_BG1 cds-NP_013706.1_BG1 99.5 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005515.1:241375-242526:- gene-YML008C_Bruggeman rna-NM_001182363.1_Bruggeman cds-NP_013706.1_Bruggeman 99.9 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005531.1:243889-245040:- gene-YML008C_CAT1 rna-NM_001182363.1_CAT1 cds-NP_013706.1_CAT1 99.6 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005371.1:234372-235523:- gene-YML008C_CBS1585 rna-NM_001182363.1_CBS1585 cds-NP_013706.1_CBS1585 99.9 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005355.1:239903-241054:- gene-YML008C_CBS436 rna-NM_001182363.1_CBS436 cds-NP_013706.1_CBS436 99.3 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005339.1:348105-349256:- gene-YML008C_CBS6412 rna-NM_001182363.1_CBS6412 cds-NP_013706.1_CBS6412 99.9 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005323.1:233627-234778:- gene-YML008C_CBS6413 rna-NM_001182363.1_CBS6413 cds-NP_013706.1_CBS6413 99.9 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001534.1:246570-247721:- gene-YML008C_CENPK1137D rna-NM_001182363.1_CENPK1137D cds-NP_013706.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005483.1:234406-235557:- gene-YML008C_EthanolRed rna-NM_001182363.1_EthanolRed cds-NP_013706.1_EthanolRed 99.9 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005547.1:237372-238523:- gene-YML008C_FaliES1 rna-NM_001182363.1_FaliES1 cds-NP_013706.1_FaliES1 99.9 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000033.1:198399-199550:+ gene-YML008C_JAY291 rna-NM_001182363.1_JAY291 cds-NP_013706.1_JAY291 99.7 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005419.1:239111-240262:- gene-YML008C_MUCL30387 rna-NM_001182363.1_MUCL30387 cds-NP_013706.1_MUCL30387 99.9 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005451.1:243772-244923:- gene-YML008C_MUCL30388 rna-NM_001182363.1_MUCL30388 cds-NP_013706.1_MUCL30388 99.9 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005291.1:234652-235803:- gene-YML008C_MUCL39482 rna-NM_001182363.1_MUCL39482 cds-NP_013706.1_MUCL39482 99.9 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005435.1:240218-241369:- gene-YML008C_MUCL42920 rna-NM_001182363.1_MUCL42920 cds-NP_013706.1_MUCL42920 99.9 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011822.1:251793-252944:- gene-YML008C_NCIM3186 rna-NM_001182363.1_NCIM3186 cds-NP_013706.1_NCIM3186 99.5 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005275.1:234587-235738:- gene-YML008C_NCYC1407 rna-NM_001182363.1_NCYC1407 cds-NP_013706.1_NCYC1407 99.9 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994152.1:240523-241674:- gene-YML008C_PE2H3 rna-NM_001182363.1_PE2H3 cds-NP_013706.1_PE2H3 99.7 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999884.1:246618-247769:- gene-YML008C_PE2H4 rna-NM_001182363.1_PE2H4 cds-NP_013706.1_PE2H4 99.7 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001145.3:251839-252990:- gene-YML008C_S288C rna-NM_001182363.1_S288C cds-NP_013706.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000005.1:285286-286437:+ gene-YML008C_SA1 rna-NM_001182363.1_SA1 cds-NP_013706.1_SA1 99.7 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005499.1:234434-235585:- gene-YML008C_ThermosaccDry rna-NM_001182363.1_ThermosaccDry cds-NP_013706.1_ThermosaccDry 99.9 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005467.1:238410-239561:- gene-YML008C_VR1 rna-NM_001182363.1_VR1 cds-NP_013706.1_VR1 99.5 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000027.1:213493-214644:- gene-YML008C_ZTW1 rna-NM_001182363.1_ZTW1 cds-NP_013706.1_ZTW1 99.9 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047499.1:245165-246316:- gene-YML008C_Sparadoxus rna-NM_001182363.1_Sparadoxus cds-NP_013706.1_Sparadoxus 93.4 99.8 Verified 1 1 1 False True False False False

Additional files